Chronic tendinopathies whether it be at the shoulder, elbow, knee, or ankle continue to perplex the Sports Medicine community. These nagging conditions have no easy fix to them which can be frustrating for both the patient and treatment team. Data in most cases does not support surgery as the answer. Thus, we continue to search for non-surgical treatments that can solve tendinopathies as quickly and effectively as possible. Unfortunately, the best answer for these conditions remains elusive. Coming to us from Stony Brook University Hospital, Drs. Salvatore Capotosto, MD & Alireza Nazemi, MD, MS present their findings on Prolotherapy, a promising option in the treatment of chronic tendinopathies.