Renal tubular acidosis, or RTA, refers to a group of disorders characterized by defective renal acid-base regulation. The capacity for normal urinary acidification is impaired, resulting in net acid retention and hyperchloremic metabolic acidosis. In this episode, Danielle Soranno, MD reviews basic mechanisms of the disease that are important for diagnosis and management of RTA in your patients.

Dr. Soranno is an Associate Professor of Pediatrics, Bioengineering, and Medicine at the University of Colorado School of Medicine and a Pediatric Nephrologist at Children's Hospital Colorado.

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