This PER® featured podcast includes a discussion with 3 experts on best practices for integrating opioid-sparing strategies into the treatment paradigm along with updates including the 2025 NOPAIN Act. The panel includes members of the care team including the surgical oncologist and anesthesiologist. This program is designed to help clinicians recognize the impact and potential harm of widespread opioid use for pain management following breast cancer surgeries and identify and understand strategies that can be implemented to mitigate the use of opioids to improve patient outcomes.