Macrocytic Anemia Macrocytic anemias produce strange dysfunctional blood cells. This will result in some hemolysis and progress to splenic dysfunction as the spleen becomes overloaded. Howell-Jolly bodies are DNA remnants seen with a macrocytic anemia or a damaged spleen. You will find them in B12 deficiency anemia, folate deficient anemia, sickle cell anemia and celiac […]

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