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This conversation explores why different nutrition interventions might help MASLD patients improve their overall liver health and what lessons treaters and researchers can learn from this. 

It starts with Louise Campbell discussing a recent publication of a pilot study from Armandi et al. (including Jörn Schattenberg as a co-author) evaluating the ability of short-term dietary gluten reduction to reduce metabolic dysfunction as measured in CAP (controlled attenuation parameter) scores. The study shows that even a short-term intervention can have a meaningful impact. The results confirm Louise’s experience with sugar-rich foods and suggest that several different diet interventions can produce valuable results. It leads to a discussion with Louise, Jörn and Hannes Hagstrom asking which change actually drives the lower CAP: gluten, associated high fructose and sugar content in the gluten-rich products, or overall calorie reduction.  To Louise, the most important idea is that interventions work best with frequent VCTE tracking and multiple diet options for patients to choose. Jörn and Roger Green concur.