What is SAPHO? What does the ‘H’ stand for, again? This episode explores some basics about the condition and delves into the history of how this disease came to be.

• Intro :01
• Welcome to another exciting episode of Rheuminations :11
• About today’s episode :17
• What does the acronym ‘SAPHO’ stand for? :37
• How do you define this condition? 2:35
• So, what is SAPHO syndrome? 4:59
• Are any of the letters specific for SAPHO syndrome? 15:20
• How the puzzle pieces were put together 15:48
• Over the next ensuing decades, when did we start realizing that patients could have dermatologic manifestations? 23:00
• So, what about hyperostosis? 30:46
• Why isn’t the Sonozaki group getting the credit? 39:22
• So, how did we get SAPHO? 40:26
• How did they get 85 patients? 42:50
• We went through a lot in this paper 45:29
• Next episode preview 46:29
• Thanks for listening 47:03

Disclosure: Brown reports no relevant financial disclosures.

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References:

Chamot AM, et al. Rev Rheum Mal Osteoartic. 1987;54:187-196.

Giedion A, et al. Ann Radiol (Paris) 1972;15:329-342.

Köhler H, et al. Ann Intern Med. 1977;87:192-194.

Nguyen MT, et al. Semin Arthritis Rheum. 2012;42:254-265.

Raposo I, Torres T. Am J Clin Dermatol. 2016;17:349-358. 

Romani M, et al. Clin Podiatr Med Surg. 2021;38:541-552. 

Sonozaki H, et al. Ann Rheum Dis. 1981;40:547-553.

Windom RE, et al. Arthritis Rheum. 1961;4:632-635.