Because COVID-19 can create a status of systemic inflammation, which can affect multiple organs, including the kidneys, the adjuvant therapy of blood purification has gained some recognition. Host Pamela Peeke is joined by Javier Neyra to discuss clinical cases and the use of extracorporeal blood purification in COVID-19 patients.

Family nurse practitioners (FNPs) who do not have acute care certification may be recruited to work in ICUs that lack enough acute care nurses, which is a challenge for both the ICU and the FNP. When the FNP moves on to another institution, that institution may not consider the FNP's ICU experience to be an adequate qualification. Host Diane C. McLaughlin, DNP, AGACNP-BC, CCRN, is joined by Christian Santos, MSN, FNP-BC, and Mariah Rose, ARNP, both nurse practitioners at Mayo Clinic in Jacksonville, Florida, to discuss the difficulties of FNPs who need acute care certification to work in ICUs. Christian Santos, MSN, FNP-BC, is a nurse practitioner at Mayo Clinic Hospital in Jacksonville, Florida, USA. Mariah Rose, ARNP, is a nurse practitioner at Mayo Clinic in Jacksonville, Florida, USA.

​This podcast discusses patients who develop acute kidney injury (AKI) and how AKI is independently associated with mortality in critically ill infants, neonates, and larger children.

BioFire FilmArray is the latest in technologies for rapidly identifying pathogens that cause Lower Respiratory Tract Infections (LRTI). Host Pamela M. Peeke, MD, MPH, FACP, FACSM, is joined by Tufik Assad M.D., M.S.C.I. to discuss how this technology can be integrated into clinical care to improve patient outcomes.

Learn about the importance of utilizing dynamic assessments of fluid responsiveness to guide treatment in patients with viral sepsis, including COVID-19, and understand how they can be used to help improve patient outcomes in sepsis patients.

Two previously published trials (ARDS et Curarisation Systematique and Reevaluation of Systemic Early Neuromuscular Blockade) presented equivocal evidence on the effect of neuromuscular blocking agent infusions in patients with acute respiratory distress syndrome.

Rapid delivery of antibiotics is a cornerstone of sepsis therapy, although time targets for specific components of antibiotic delivery are unknown. Host Ludwig H. Lin, MD, is joined by Stephanie Parks Taylor, MD, to discuss the significance of time lead for suspected sepsis patients, how to use a generous time window wisely, and new and reconfigured technologies opportunities.

The prevalence and consequences of dyssynchronies are largely underestimated due to frequent lack of monitoring.

Enteral feed intolerance occurs frequently during enteral nutrition delivery in the critically ill and is associated with lower enteral nutrition delivery and worse clinical outcomes.

Extubation is a high-risk endeavor in some COVID-19 patients. Host Pamela M. Peeke, MD, MPH, FACP, FACSM, is joined by Joshua H. Atkins, MD, PhD; Christopher Rassekh, MD; and Ara Chalian, MD, to discuss recognizing risks surrounding extubation in ventilated COVID-19 patients.