Sensible Medicine

Sensible Medicine episodes:

• 04.30.2024

  A Discussion with Dr. Dena Zeraatkar regarding analytic flexibility in observational studies

  Gosh was this a great conversation about her recent paper on specification curve analysis of nutritional observational studies. Here is Dr. Zeraatkar’s bio: Dena Zeraatkar, PhD is an Assistant Professor in the Departments of Anesthesia and Health Research Methods,...

  
• 04.12.2024

  Friday Reflection 38: Yesterday’s Solutions; Today’s Problems

  The Thomas Sowell quote, “On closer scrutiny, it turns out that many of today's problems are a result of yesterday's solutions” has been ringing in my head a lot lately. This is a public episode. If you’d like to discuss...

  
• 04.04.2024

  Yet Another Excellent Explainer About P-Values in Randomized Trials

  Gosh was I lucky to speak with Professor Erik Van Zwet from Leiden University in the Netherlands. He is the first author on a recent NEJM Evidence paper looking at more than 23,000 trials in the Cochrane Database. (I linked...

  
• 03.08.2024

  Friday Reflection 37: Why I Teach (acceptable and less acceptable reasons)

  Why have I been committed to medical education? Some of the reasons are admirable but not terribly novel. Others are a bit hard to admit, but just as true. This is a public episode. If you’d like to discuss this...

  
• 02.02.2024

  Friday Reflection 36: Why Don’t Doctors Want to See Patients?

  Friday Reflection 35: Why Don’t Doctors Want to See Patients? I was asked “Why is it that doctors don’t want to see patients?” and I could not answer the question. Fourteen months later, here is my response. This is a...

  
• 01.25.2024

  New Austrian Study Shows Boosters do NOT reduce COVID19 deaths in people who had COVID

  This is a public episode. If you’d like to discuss this with other subscribers or get access to bonus episodes, visit www.sensible-med.com/subscribe

  
• 01.18.2024

  Math Professor Ben Recht and I Discuss P-values and Confidence Intervals

  Ben Recht is a professor at UC Berkeley. You know, the place that has all those parking spaces for the Nobel laureates. He understands the innards of math. And that is exactly why he explained that doctors who use...

  
• 12.22.2023

  A discussion with the primary investigator of the world's first placebo-controlled AF ablation trial

  As many of you know, I have long argued (unsuccessfully until now) for a placebo-controlled trial of AF ablation. One group gets the ablation; the other gets a placebo or sham procedure. This way we can sort out the placebo-resistant...

  
• 12.17.2023

  Mandrola and Prasad are back

  This is a public episode. If you’d like to discuss this with other subscribers or get access to bonus episodes, visit www.sensible-med.com/subscribe

  
• 12.17.2023

  Mandrola and Prasad are back

  This is a public episode. If you’d like to discuss this with other subscribers or get access to bonus episodes, visit www.sensible-med.com/subscribe

  
• 12.15.2023

  Friday Reflection 35: Four Who Fired Me

  These patients did the right thing leaving my care. We were wrong for each other, or I had given what I had to offer (at the time) and it was not enough. That does not lessen the feeling that I...

  
• 11.03.2023

  Friday Reflection 32: The Trauma of Not Dying Alone

  They say dying alone is sad. They also say we all die alone. There is trauma to not dying alone as well.  This is a public episode. If you’d like to discuss this with other subscribers or get access to...

  
• 11.01.2023

  Soren Diederichsen on Atrial Fibrillation Screening

  If you care about AF you will love this conversation. Soren has some interesting ideas about what AF is now vs what AF was in the past. Here are some links:The LOOP Study (which was non-significant). Effects of...

  
• 10.23.2023

  Andrew Foy has a Different Conclusion on a Big JAMA paper on CV risk reduction

  The study in question is a randomized clinical trial looking at the Million Hearts Model. This model paid health care organizations to assess and reduce CV risk. Obviously, this is an important goal. Heart disease, specifically, atherosclerotic vascular disease,...

  
• 10.20.2023

  Friday Reflection 31: Senses, Memories, and Medicine

  Friday Reflection 31: Senses, Memories, and Medicine Medical training introduced me to a whole menu of smells -- both diagnostic tools and reminders of times in my career. This is a public episode. If you’d like to discuss this...

  
• 10.18.2023

  Sudden cardiac death and arrhythmias in athletes

  Sudden cardiac death due to ventricular rhythm disturbances are rare but highly public. It’s strange and curious because you don’t expect healthy athletes to suffer serious cardiac issues. Recently three prominent athletes have survived sudden cardiac death. Christian Erikson,...

  
• 10.16.2023

  Prasad's lecture gets cancelled/ Cifu Gets COVID

  This is a public episode. If you’d like to discuss this with other subscribers or get access to bonus episodes, visit www.sensible-med.com/subscribe

  
• 10.05.2023

  New Podcast -- Discussion with Rita Redberg and Angela Lu regarding Their Study on Conflict of Interest

  Angela Lu is training to be a physician. She’s interested in public policy. As a third year medical student, she teamed up with established leaders to ask a unique question regarding public disclosure of financial relationships. When the...

  
• 09.27.2023

  Foy and Mandrola Talk Coronary Calcium and a New Super-Exciting Approach to Medical Education

  Andrew Foy rejoins the Sensible Medicine podcast. We talk first about coronary artery calcium. Andrew is an expert in this area. We have co-written our case against CAC scoring for any cause in the American Family Physician. It’s had...

  
• 09.19.2023

  Foy and Mandrola Discuss AF, AF-Ablation, Sham-controls, Evidence Translation and Heterogenous Treatment Effects

  This week, I talk with Andrew Foy, who is an academic cardiologist at Penn State University in Hershey, PA. Andrew is one of the smartest voices in medicine today. We start with the REMEDIAL trial, published recently in JAMA....

  
• 09.11.2023

  Coumadin beats DOAC, ECMO fails, When RCTs needed, Bad COVID Policy

  This is a public episode. If you’d like to discuss this with other subscribers or get access to bonus episodes, visit www.sensible-med.com/subscribe

  
• 09.08.2023

  Friday Reflection 29: The Totally Predictable Doctor as Patient Essay

  This is a public episode. If you’d like to discuss this with other subscribers or get access to bonus episodes, visit www.sensible-med.com/subscribe

  
• 08.29.2023

  Sensible Medicine x Vaccine Curious: Tracy Beth Høeg and Christine Stabell Benn compare US & Danish COVID-19 response and child vaccination policy

  Sensible Medicine Sensible Medicine x Vaccine Curious Cross Podcast on the USA vs Denmark, vaccines, etc: Show notes by Dovid Y Rimmer, Tracy Beth Høeg and Christine Stabell Benn * Benn, Høeg. Regarding becoming a medical skeptic. Hoeg: anonymous blog...

  
• 08.25.2023

  Friday Reflection 28: Four of the Things Patients Have Taught Me

  Although it is unoriginal to point out that doctors learn from our patients, here are a few lessons so powerful, so extrapolatable, that I forever associate them with an individual. This is a public episode. If you’d like to discuss...

  
• 08.23.2023

  Mandrola & Prasad on Republicans and COVID outcomes, Journals and stenting

  This is a public episode. If you’d like to discuss this with other subscribers or get access to bonus episodes, visit www.sensible-med.com/subscribe

  
• 08.20.2023

  A Conversation with Professor Robert Yeh

  Here is the profile for Harvard Professor Robert (Bobby) Yeh. His most recent Circulation paper: Bringing the Credibility Revolution to Observational Research in Cardiology. We referenced a paper by Professor Miguel Hernan: The C-Word: Scientific Euphemisms Do Not...

  
• 08.11.2023

  Friday Reflection 27: The Poor Historian

  BW was a 66-year-old woman who presented for an urgent visit to the general medicine clinic. She reported that she had been having dizziness for the last four days. When pressed, she said it occurred intermittently, being present more than...

  
• 07.28.2023

  Friday Reflection #26: General Internal Medicine in the Time of COVID

  There is something valuable about learning to adapt old skills to novel situations. This is a public episode. If you’d like to discuss this with other subscribers or get access to bonus episodes, visit www.sensible-med.com/subscribe

  
• 07.27.2023

  Podcast discussion on Nutrition Science, HFpEF and the NYT article on treatment of PAD

  Adam and I discuss three topics I) The MIND Trial published in NEJM. Does a special diet reduce the future risk of cognitive decline? II) HFpEF — I am speaking at a congress on heart failure with preserved ejection...

  
• 07.14.2023

  Friday Reflection 25: The Advice I’d Like to Give a Student Entering Medical School

  Four pieces of advice nobody asked for.  This is a public episode. If you’d like to discuss this with other subscribers or get access to bonus episodes, visit www.sensible-med.com/subscribe

  
• 06.30.2023

  Friday Reflection 24: I Would Rather Go Back in Time

  KW was a 58-year-old man with long standing type 1 diabetes mellitus and hypertension. He came to an appointment one Friday afternoon with chest pain. The pain had been present intermittently for 10 days. It was on the left side...

  
• 06.28.2023

  Sensible medicine

  This is a public episode. If you’d like to discuss this with other subscribers or get access to bonus episodes, visit www.sensible-med.com/subscribe

  
• 06.16.2023

  Friday Reflection 23: The Ghost Patient Panel

  This ghost panel is made up of people who used to be my patients but no longer are — people who left my practice without telling me.  This is a public episode. If you’d like to discuss this with other...

  
• 06.13.2023

  Medical Conservatism, the ELAN Trial, and Residents Striking

  Links The Case for Being a Medical Conservative https://www.amjmed.com/article/S0002-9343(19)30167-6/fulltext ELAN Trial https://www.nejm.org/doi/full/10.1056/NEJMoa2303048 Mandrola on NYC Residents’ Strike https://www.medscape.com/viewarticle/992607 This is a public episode. If you’d like to discuss this with other subscribers or get access to...

  
• 06.05.2023

  Medical Evidence, Hype, Cancer Drugs, Conflict

  This is a public episode. If you’d like to discuss this with other subscribers or get access to bonus episodes, visit www.sensible-med.com/subscribe

  
• 06.02.2023

  Friday Reflection 22: The Memory Binder

  I visit the binder to pay my respects, to learn, to reminisce, and to trace the arc of my career. This is a public episode. If you’d like to discuss this with other subscribers or get access to bonus...

  
• 05.26.2023

  A Heartfelt Plea to Become A Primary Care General Internist

  Medicine in America will be better, more humane, and more affordable with more good, smart, dedicated primary care physicians. Be part of the solution.  This is a public episode. If you’d like to discuss this with other subscribers or get...

  
• 05.22.2023

  Seeding trials/ Choosing Students

  This is a public episode. If you’d like to discuss this with other subscribers or get access to bonus episodes, visit www.sensible-med.com/subscribe

  
• 05.19.2023

  Friday Reflection #21: Revealing Ignorance

  Why did it take years for me to reach a time in my career when I am comfortable admitting knowledge gaps? This is a public episode. If you’d like to discuss this with other subscribers or get access to bonus...

  
• 05.08.2023

  Mandrola gives VP Health Advice

  This is a public episode. If you’d like to discuss this with other subscribers or get access to bonus episodes, visit www.sensible-med.com/subscribe

  
• 05.05.2023

  Friday Reflection 20: The Clinical Set Point

  When patients meet a new doctor, both patient and doctor should be aware of each other’s philosophy.  This is a public episode. If you’d like to discuss this with other subscribers or get access to bonus episodes, visit www.sensible-med.com/subscribe

  
• 05.02.2023

  The Great Chat GPT debate

  This is a public episode. If you’d like to discuss this with other subscribers or get access to bonus episodes, visit www.sensible-med.com/subscribe

  
• 05.01.2023

  Great CHAT GPT debate

  Get full access to Sensible Medicine at sensiblemed.substack.com/subscribe

  
• 04.24.2023

  Medical uncertainty, 7th dose, ABIM and Modules

  This is a public episode. If you’d like to discuss this with other subscribers or get access to bonus episodes, visit www.sensible-med.com/subscribe

  
• 04.14.2023

  Friday Reflection 19: A Pledge That Can Be Hard to Honor

  This is a public episode. If you’d like to discuss this with other subscribers or get access to bonus episodes, visit www.sensible-med.com/subscribe

  
• 04.10.2023

  RSV vaccines/ Mifepristone/ Overtreatment/ Long COVID

  This is a public episode. If you’d like to discuss this with other subscribers or get access to bonus episodes, visit www.sensible-med.com/subscribe

  
• 04.03.2023

  Chat GPT - Medical Journals - Treating early disease states

  Chat GPT - Medical Journals - Preventive medicine This is a public episode. If you’d like to discuss this with other subscribers or get access to bonus episodes, visit www.sensible-med.com/subscribe

  
• 03.31.2023

  Friday Reflection #18: An Homage to Mentors

  This is a public episode. If you’d like to discuss this with other subscribers or get access to bonus episodes, visit www.sensible-med.com/subscribe

  
• 03.17.2023

  Friday Reflection 17: The Grace of the Dying

  This is a public episode. If you’d like to discuss this with other subscribers or get access to bonus episodes, visit www.sensible-med.com/subscribe

  
• 03.13.2023

  Can you Exercise Too Much/ Shredding Trust in Public Health

  Mandrola, Prasad and Hoeg are back to talk about a new exercise study— can you do too much— and then COVID19 pandemic errors. This is a public episode. If you’d like to discuss this with other subscribers or get...