1) C90RF72 mutations and 2) Topic of the month: Bedside Neuro-ophthalmology. This podcast for the Neurology Journal begins and closes with Dr. Robert Gross, Editor-in-Chief, briefly discussing highlighted articles from the print issue of Neurology. In the second segment Dr. Ted Burns with Drs. Sharon Sha and Carol Dobson-Stone about their papers on frontotemporal dementia. Dr. Stacey Clardy is reading our e-Pearl of the week about Hanes sign. In the next part of the podcast Dr. Beau Bruce interviews Dr. Randy Kardon about relative afferent papillary defect. Dr. Bruce will interview Dr. Kardon next week about "big pupil" consult. The participants had nothing to disclose except Drs. Burns, Dobson-Stone, Clardy, Bruce and Kardon.Dr. Burns serves as Podcast Editor for Neurology®; performs EMG studies in his neuromuscular practice (30% effort); and has received research support from the Myasthenia Gravis Foundation of America and Knopp Neurosciences Inc..Dr. Dobson-Stone receives research funding from the National Health and Medical Research Council (Australia).Dr. Clardy serves on the editorial team for the Neurology® Resident and Fellow Section. Dr. Bruce received research funding from the NIH.Dr. Kardon serves on the editorial board for Journal of Neuro-ophthalmology and Archives of Ophthalmology; has patents for method of characterizing focal pupil responses to light and method of assessing retinal function using infrared optical signals in response to light; receives royalties for the publication of Tissues and Organs: A text-atlas of scanning electron microscopy and for use of micrographs in other textbooks; is a consultant for Novartis Pharmaceuticals Ltd; receives research support from the Department of Veterans Affairs Iowa City Center of Excellence for the Prevention and Treatment of Visual Loss, Department of Defense Vision Research Program (TATRC) and Department of Veterans Affairs Rehabilitation Division.