DiabetesBio

Stilgenbauer & Sadagurski on the link between airborne pollutants and metabolic disease, Petersen on the effect of weight loss on skeletal muscle bioactive lipids, and Page & Alves on the neurodevelopmental pathways to obesity and type 2 diabetes.


Listen Later

Welcome to the December 2024 episode of DiabetesBio—the American Diabetes Association’s podcast for its flagship research publication, Diabetes. In this episode of DiabetesBio, Drs. Kirk Habegger, Darleen Sandoval, and Kevin Williams discuss the latest and greatest content in the December 2024 issue of Diabetes

0:55 In celebrating the one-year anniversary of DiabetesBio, our hosts highlight a few of their favorite articles from the last year. These include: 

  • Ueki et al. Establishment of Pancreatic β-Cell–Specific Gene Knockout System Based on CRISPR-Cas9 Technology With AAV8-Mediated gRNA Delivery doi.org/10.2337/db23-0445
  • Bruce et al. The Effect of Small Increases in Blood Glucose on Insulin Secretion and Endogenous Glucose Production in Humans doi.org/10.2337/db24-0388
  • Furber et al. GIPR Agonism Enhances TZD-Induced Insulin Sensitivity in Obese IR Mice doi.org/10.2337/db23-0172
  • Greenbaum et al. Evolving Concepts in Pathophysiology, Screening, and Prevention of Type 1 Diabetes: Report of Diabetes Mellitus Interagency Coordinating Committee Workshop doi.org/10.2337/dbi24-0020
  • Ramos et al. Role of Cardiorespiratory Fitness and Mitochondrial Oxidative Capacity in Reduced Walk Speed of Older Adults With Diabetes doi.org/10.2337/db23-0827
  • Bonifazi et al. Development of Novel Tools for Dissection of Central Versus Peripheral Dopamine D2-Like Receptor Signaling in Dysglycemia doi.org/10.2337/db24-0175

6:15 Darleen is joined by Lukas Stilgenbauer of the Department of Biological Sciences at Wayne State University in Detroit, Michigan, as well as Mariana Sadagurski, associate professor in the Institute of Environmental Health Sciences and Integrative Biosciences Center at Wayne State University.  They discuss their article “Microglia Mediate Metabolic Dysfunction From Common Air Pollutants Through NF-κB Signaling.” This article is available for free at doi.org/10.2337/db24-0110

33:45 Kirk and Kevin dive into the December issue’s Paper of the Month, “Effect of Weight Loss on Skeletal Muscle Bioactive Lipids in People With Obesity and Type 2 Diabetes.” They’re joined by lead author Max Petersen, an instructor at the Division of Endocrinology, Metabolism, & Lipid Research at Washington University School of Medicine in St. Louis, Missouri. The article is available for free at doi.org/10.2337/db24-0083.

47:20 Finally, this month’s edition of Sweet Talk focuses on work funded by the American Diabetes Association’s Pathway to Stop Diabetes initiative. Kathleen Alanna Page, Associate Professor of Medicine at the University of Southern California’s Keck School of Medicine, and Jasmin Alves, a postdoctoral research fellow with Page, stop by to discuss Page’s study, “Neurodevelopmental Pathways to Obesity and Type 2 Diabetes: Insights From Prenatal Exposure to Maternal Obesity and Gestational Diabetes Mellitus: A Report on Research Supported by Pathway to Stop Diabetes.” The article is available at doi.org/10.2337/dbi24-0012

To learn more about Diabetes and DiabetesBio, please visit diabetesjournals.org/diabetes. Thank you for listening, and don’t forget to smash that “follow” button!

...more
View all episodesView all episodes
Download on the App Store

DiabetesBioBy American Diabetes Association

  • 5
  • 5
  • 5
  • 5
  • 5

5

1 ratings


More shows like DiabetesBio

View all
Science Magazine Podcast by Science Magazine

Science Magazine Podcast

823 Listeners

This American Life by This American Life

This American Life

91,080 Listeners

The Moth by The Moth

The Moth

27,278 Listeners

Freakonomics Radio by Freakonomics Radio + Stitcher

Freakonomics Radio

32,159 Listeners

99% Invisible by Roman Mars

99% Invisible

26,193 Listeners

Diabetes Core Update by American Diabetes Association

Diabetes Core Update

102 Listeners

Hidden Brain by Hidden Brain, Shankar Vedantam

Hidden Brain

43,701 Listeners

Frankly Speaking About Family Medicine by Pri-Med

Frankly Speaking About Family Medicine

259 Listeners

The Curbsiders Internal Medicine Podcast by The Curbsiders Internal Medicine Podcast

The Curbsiders Internal Medicine Podcast

3,334 Listeners

The Proof with Simon Hill by Live better for longer

The Proof with Simon Hill

2,611 Listeners

The Peter Attia Drive by Peter Attia, MD

The Peter Attia Drive

8,120 Listeners

Huberman Lab by Scicomm Media

Huberman Lab

29,186 Listeners

The Ezra Klein Show by New York Times Opinion

The Ezra Klein Show

16,225 Listeners

The Weekly Show with Jon Stewart by Comedy Central

The Weekly Show with Jon Stewart

10,841 Listeners

Diabetes Care "On Air" by American Diabetes Association

Diabetes Care "On Air"

13 Listeners