ZOE Science & Nutrition

The 3 biggest myths about anti-aging skincare | Prof. John McGrath


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From collagen powders to $100 creams, the skincare industry thrives on promises. However, many of the products we rely on for younger, healthier skin are built on shaky evidence. In this episode, world-renowned dermatologist Professor John McGrath breaks down what’s real and what’s not.

We explore how skin truly ages, what happens beneath the surface, and why some popular treatments don’t do what they claim. John dismantles three of the biggest myths in skincare, including the truth about SPF, collagen, and “bio-active” ingredients that never make it past the top layer of your skin.

Professor McGrath is a Professor of Molecular Dermatology at King’s College London and editor of the British Journal of Dermatology. His research has transformed how we understand genetic skin disorders and vitamin D’s role in skin health.

This conversation is packed with surprising insights - and one daily step that really does support healthier skin as you age.

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Timecodes

Timecodes

00:00 Can you reverse sunburn in 24 hours?
00:54 The anti-aging skincare routine that actually works
02:21 Is collagen powder a scam?
03:33 Your skin renews itself every 4 weeks
05:11 70 billion microbes live on your skin
07:56 Can gut bugs really reverse hair loss?
09:12 The two ways your skin actually ages
11:03 Why your skin stops repairing itself
13:19 What makes your skin sag as you age
14:55 Can lifestyle really slow down skin aging?
16:15 The enzyme that smoking activates to destroy collagen
17:01 Does vaping wreck your skin too?
18:04 Why expensive creams don’t erase wrinkles
19:21 Why most anti-aging products don’t penetrate your skin
20:41 The skincare label trick: “appearance of wrinkles”
24:03 The white bottle effect: how packaging influences trust
27:55 The double-edged sword of sunlight
30:22 Why sunlight makes you feel amazing
32:53 Could sun exposure actually protect your heart?
35:01 Are we protecting our skin too much?
39:12 The 3 steps of a dermatologist-approved routine
42:05 Are you using enough sunscreen? (Probably not)
44:55 Should you wear SPF in winter?
50:01 The vitamin D3 sunburn recovery hack
52:58 How much is too much vitamin D?


📚Books by our ZOE Scientists

The Food For Life Cookbook

Every Body Should Know This by Dr Federica Amati

Food For Life by Prof. Tim Spector


Free resources from ZOE

Live Healthier: Top 10 Tips From ZOE Science & Nutrition

Gut Guide - For a Healthier Microbiome in Weeks 


Mentioned in today's episode

Genome-wide association study identifies 143 loci associated with 25 hydroxyvitamin D concentration, Nature Communications (2020)

Topical tretinoin for treating photoaging: A systematic review of randomized controlled trials, Int J. Womens Dermatology (2022)

Sunlight Has Cardiovascular Benefits Independently of Vitamin D, Blood Purification (2016)


Have feedback or a topic you'd like us to cover? Let us know here.

Episode transcripts are available here.

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