What if we could add 20 healthy years to human life? 

This episode is brought to you by AgelessRx, where aging becomes a puzzle that can be solved. The mission is to help you live longer and healthier by adding more life to your years through science-backed solutions and personalized care. Learn more at https://agelessrx.com/.  

That’s the ambitious challenge behind the XPRIZE Healthspan competition, where 20 finalist teams are racing to find breakthroughs that could fundamentally change how we age. Driven by the moonshot vision championed by Peter Diamandis, the goal isn’t simply to live longer, it’s to preserve muscle, cognitive, and immune function as we get older.

In this episode, Jamie Justice takes us on a journey to better understand the XPRIZE competition as we take a closer look at Minicircle (Walter Patterson), Longeveron (Brian Rash), NYC Vita (Miriam Merad), Mitochondrial All Stars (David Brown), AgelessRx (Stefanie Morgan and Anar Isman), Ani.Ai (Bruno Balen), and Goqii (Vishal Gondal), exploring their very different approaches to extending healthy lifespan. From gene therapies and mitochondrial interventions to stem cells, AI-powered discoveries, and personalized health solutions, these teams are pushing longevity science into fascinating and largely uncharted territory.

Dr. Jamie Justice is a geroscience researcher and Executive Vice President of Health at XPRIZE, where she leads the organization’s efforts to accelerate breakthroughs in healthy aging.

⏱ Timestamps

00:00 Intro

00:10 What Is the XPRIZE Competition?

04:09 Why XPRIZE Isn’t a Traditional Funding Program

05:37 The XPRIZE’s Approach to Innovation

08:27 Peter Diamandis on the XPRIZE Winner

08:54 Why the Moonshot Has to Be Daring

10:31 What Makes a Breakthrough Solution?

12:44 The Different XPRIZE Categories

13:54 Can More Teams Still Join?

15:24 Clinical Trials Must Finish by 2029

18:24 The Rise of AI Based Interventions

19:11 Unexpected Approaches to Healthspan

22:07 Minicircle: The Non Viral Plasmid DNA Vector

Minicircle

24:53 Why Minicircle’s Gene Therapy Approach Is Different

25:42 A Simpler Gene Therapy Platform

26:29 Why Plasmid Gene Therapy May Be Safer

28:57 The Challenges of Gene Therapy

30:39 Pushback Against Gene Therapy

33:04 The Future of Gene Therapy

34:18 How Teams Are Adapting

36:17 What It Takes to Reach the 20 Year Goal

37:17 No More New Teams in 2028

38:27 Why Some European Teams Are Struggling

40:56 Could Teams Merge to Move Forward?

42:07 Inside the Biologic Category

Longeveron

42:39 The Next Generation of Biologic Therapies

46:50 What Makes This Team Unique?

47:48 Engineering New Biologic Therapies

53:56 Building a Super Team for Healthspan

Featured Team: Mitochondrial All Stars

57:28 The Role of Mitochondria in Aging

59:27 Specializing in Mitochondrial Health

01:00:48 The Power of a Multi Modal Team

NYC Vita

01:03:11 Combining Different Approaches to Aging

01:06:37 Sharing Data Across Teams

01:08:50 Why Collaboration Could Change the Game

01:13:33 A Novel Drug Target for Aging

AgelessRX

01:14:59 A Strategic Approach to Intervention

01:15:52 Can We Achieve 20 Years of Rejuvenation?

01:17:18 The Chemical Combination

01:22:12 The Science Behind the Approach

01:22:46 The Potential of NAD+

01:23:58 Why Japanese Teams Stand Out

01:26:18 The $100 Million Incentive

01:28:10 Inside the Drug Category

01:31:57 Can We Add Healthy Life in One Year?

Ani.Ai 

01:32:49 Healthy Life in Just One Year

01:33:22 The Antibiome Approach

01:36:52 What the Future of Healthspan Could Look Like

01:38:37 The Best Piece of Advice

Connect with Jamie

Website: https://www.xprize.org/ 

Instagram: https://www.instagram.com/j.n.justice/ 

LinkedIn: https://www.linkedin.com/in/jamie-justice-ph-d-6b933146 

X: https://x.com/j_n_justice  

The Teams:

Minicircle: https://minicircle.io/

Longeveron: https://longeveron.com/ 

NYC Vita: https://www.mountsinai.org/ 

AgelessRX: https://agelessrx.com/ 

Ani.Ai: https://www.ani.ai/ 

Goqii: https://goqii.com/us-en 

Is democracy already becoming obsolete in the age of AI?

Emad Mostaque, founder of Intelligent Internet, shares why he believes the status quo is over, why democracy as we know it cannot survive the rise of superintelligent AI, and why the race for AGI could determine who controls the future of humanity.

In this clip, Emad explains why AI may eventually replace human decision-making, how power is becoming concentrated in the hands of a few AI companies, and why governments must rethink ownership, governance, and the role of AI before it's too late.

Watch the full episode here: https://open.spotify.com/episode/6oqWQWDYX90uQUmZ5hcB4Q?si=2ada02e898e44ea6

What if the key to aging better is taking care of your body's batteries?

For 20% off all Timeline products, go to timeline.com/beyondtomorrow

Dr. Singh explains why mitochondrial health is becoming a major focus in longevity science. He unpacks the research behind urolithin A, how it supports cellular renewal, and why supplements should never replace the basics.

The conversation covers the habits that matter most, from exercise and sleep to fasting and gut health. They also explore how to separate real science from longevity hype.

Finally, they look ahead to the future of healthy aging, where better diagnostics, AI, and preventive medicine could help us stay healthier for longer, not just live longer.

Dr. Singh is the Chief Medical Officer at Timeline and a physician-scientist specializing in immunology, mitochondrial health, and longevity. His research focuses on translating cutting-edge science into evidence-based interventions that help people age healthier.

What You’ll Learn

• Why mitochondrial health matters for longevity

• How urolithin A supports healthy aging

• The habits that have the strongest evidence

• How to spot longevity hype

• Where longevity science is headed next

⏱ Timestamps

00:00 Intro

00:14 Why Urolithin A Matters

02:20 The Best Ways to Boost Mitochondria

03:20 Can We Reverse Aging?

06:37 Why Your Immune System Ages First

08:20 Targeting the Hallmarks of Aging

10:53 Fifteen Years, One Mission

12:24 The Search for a Longevity Superfood

15:26 Do You Really Need Supplements?

17:58 Three Ways to Improve Mitochondrial Health

20:02 Creatine + Urolithin A Explained

21:41 What Early Users Reported

24:13 Where Skincare Meets Longevity

25:42 Why Longevity Takes Time

28:15 The Three Pillars of Healthy Aging

30:01 The Shift to Preventive Medicine

31:50 Why Mitochondria Are Going Mainstream

34:35 Mitophagy vs. Autophagy

35:38 How Antibiotics Affect Aging

37:49 Rebuilding Your Gut Microbiome

39:59 Prebiotics vs. Probiotics vs. Postbiotics

42:11 The Most Underrated Longevity Habit

43:30 The Gut-Brain Connection

45:04 Melatonin and Mitochondrial Health

45:58 The Biggest Longevity Myth

46:35 Why Metabolic Health Matters

48:19 When GLP-1 Drugs Make Sense

49:32 The Hidden Downsides of GLP-1s

51:12 What Centenarians Can Teach Us

52:48 Mitochondrial Health in 2031

54:17 If Tomorrow Is Your Last Day...

Connect with Dr. Singh

Website: https://www.timeline.com/ 

Connect with Julian

Instagram: https://www.instagram.com/thebeyondtomorrowpodcast/  

Instagram: https://www.instagram.com/juliankissa/  

LinkedIn: https://uk.linkedin.com/in/julian-issa  

Website: www.beyondtomorrowpodcast.com 

Email: [email protected] 

Subscribe on Spotify, Apple, and YouTube for more stories from the edge of what is possible.

Could AGI arrive within the next three to four years and super-intelligence follow almost immediately?

Emad Mostaque, founder of Intelligent Internet, explains why he believes the first stage of the singularity has already begun, why recursive self-improvement could accelerate AI from AGI to ASI in as little as a day, and why the convergence of AI and quantum computing could transform the world faster than most people expect.

In this clip, Emad reveals why leading AI experts believe AGI is rapidly approaching, how today’s models are already outperforming top programmers, and why many jobs could become economically irrelevant within the next 1,000 days.

Watch the full episode here: https://open.spotify.com/episode/6oqWQWDYX90uQUmZ5hcB4Q?si=9bf0fbe2159246c5

What happens when intelligence stops being uniquely human?

I’m really excited to announce our new sponsor, AgelessRx, a leading longevity telehealth platform that connects you with licensed clinicians for evidence-based treatments.  Get 20% off your first order at agelessrx.com using code BEYONDTOMORROW

AI may be changing more than how we work. Joscha Bach argues that it could fundamentally reshape how we think, relate to others, and understand ourselves. The future may be difficult to predict because technology is changing the very models we use to understand it.

The conversation moves from AI agents and universal basic intelligence to consciousness and agency. Bach explores whether machines could become more than tools, and whether AI might eventually extend human minds and biology onto new substrates.

But the biggest question may not be whether AI becomes conscious. It is whether humanity can build and govern these systems wisely. Bach argues that AI could make society more capable, but only if we develop better incentives, stronger long-term thinking, and a positive vision for the future.

Joscha Bach is a computer scientist, philosopher, and researcher focused on artificial intelligence, cognition, and machine consciousness. He founded the California Institute for Machine Consciousness to explore how minds can self-organize through controlled experiments.

What You’ll Learn

• Why the AI revolution may be bigger than previous technological shifts

• How AI could become an extension of human intelligence

• Why agency may matter more than machine consciousness

• How the brain creates a simulated model of reality

• Whether consciousness could emerge on different substrates

• Why AI alignment is also a problem of human alignment

• How AI could help humanity become smarter and more coherent

  
  

⏱ Timestamps

00:00 Intro

00:09 What Happens When AI Escapes?

02:08 Can AI Become Your Second Mind?

05:30 The Rise of Universal Basic Intelligence

07:42 Will AI Make Everyone Smarter?

10:52 Doomers vs. AI Companies

16:15 Why AI Progress Surprised Everyone

17:27 Why Nobody Believed in AI

21:00 Could AI Become Smarter Than Humans?

27:23 Your Brain Is Running a Simulation

29:01 Does AI Really Need Consciousness?

32:48 AI Could Help Build a Better World

36:24 AI Is the Interactive Internet

38:22 Is Humanity Running Out of Time?

41:03 What Is AI’s Greatest Risk?

43:46 We Are the AI

45:30 Why China Could Lead AI

48:17 Why Elon Builds What Others Won’t

51:17 Who Controls How Smart AI Gets?

55:47 Can AI Threaten Our Freedom?

57:13 Why Does Everyone Fear AI Doom?

01:00:33 The AI Panopticon Is Coming

01:04:48 AI Is Already Surpassing Experts

01:06:14 Can AI Actually Destroy the World?

01:08:21 Why AI Experts Disagree

01:09:09 Is Death Real in a Simulation?

01:09:36 Do Minds Really Have Identity?

01:11:55 Can Claude Actually Feel?

01:14:06 Is the Universe a Computer?

01:15:45 What’s the Best Advice You’ve Received?

01:17:58 Is Free Will Just Psychological?

01:19:06 If Tomorrow Was Your Last Day...

Connect with Joscha

Website: http://bach.ai/ 

Substack: https://joscha.substack.com/ 

LinkedIn: https://www.linkedin.com/in/joschabach/ 

X: https://x.com/Plinz  

Connect with Julian

Instagram: https://www.instagram.com/thebeyondtomorrowpodcast/  

Instagram: https://www.instagram.com/juliankissa/  

LinkedIn: https://uk.linkedin.com/in/julian-issa  

Website: www.beyondtomorrowpodcast.com 

Email: [email protected] 

Subscribe on Spotify, Apple, and YouTube for more stories from the edge of what is possible.

Can we really live to 180 or even beyond?

This episode is brought to you by NADclinic.com, the go-to destination for longevity and human performance. Check out their new NADair, a next-gen, precision breath-activated NAD⁺ wellness system using multi-patented DPI technology: https://nadairx.com/ 

Dave Asprey believes the future of longevity is arriving much faster than most people realize. He explains why personalized medicine, gene therapies, AI, and biohacking could fundamentally change how we age, and why simply extending healthspan isn't an ambitious enough goal.

From peptides and GLP-1 drugs to creatine, sleep, brain optimization, and nutrition, Dave challenges conventional wisdom on nearly every aspect of health. He argues that the future of medicine won't be based on population averages, but on personalized interventions tailored to each individual's biology.

He also shares why biohacking became a global movement, why embracing calculated risk is essential for progress, and why the biggest breakthrough in longevity may come from giving people greater control over their own health decisions.

Dave Asprey is an entrepreneur, author, and the founder of the biohacking movement. He is the creator of Danger Coffee, a multiple-time bestselling author, and one of the world's leading voices on longevity, cognitive performance, and human optimization.

What You’ll Learn

• Why Living to 180 Is Just the Beginning

• How Personalized Medicine Is Changing Longevity

• The Future of Gene Therapy, Peptides & Biohacking

• GLP-1, Creatine & The Next Generation of Health

• Why Biohacking Is Becoming a Global Movement

• The Biggest Longevity Mistakes Most People Make

  
  

⏱ Timestamps

00:00 Intro

00:04 Can You Really Live to 180?

01:46 How Epigenetics Prevents Aging

04:08 Why Taking Risks Extends Life

05:06 The Truth About N=1 Health

07:54 Are Side Effects Overblown?

09:39 Why Biohacking Won

13:26 Biohacking Was Never About Supplements

15:34 Track What You Hack

17:28 Are Peptides Actually Dangerous?

20:10 The Two Minds Controlling Your Body

23:16 Why Governments Should Fund Peptide Research

24:48 Could GLP-1 Slow Aging?

28:09 Why Dave Quit Veganism

30:11 Is Too Much Olive Oil Harmful?

31:42 Is Beef Tallow Actually Healthy?

33:09 The Truth About Creatine

35:01 How Much Creatine Do You Really Need?

36:07 Do You Really Need 8 Hours of Sleep?

39:53 The Best Cognitive Enhancers

41:02 Psychedelics and Human Consciousness

43:50 Can Your Organs Regrow?

47:23 The Future of Stem Cell Therapy

52:45 Is NAD Worth Taking?

54:19 Lessons From Divorce and Co-Parenting

56:17 The Secret to Lasting Happiness

57:48 Choose Your Partner Carefully

59:03 Dave's Long-Term Biohacking Plan

01:00:05 Is Living Forever a Curse?

01:01:37 Does Reincarnation Exist?

01:02:44 Are We Living in a Simulation?

01:05:36 What Psychedelics Really Taught Me

01:06:59 Low-Dose Nicotine for Longevity?

01:08:27 Why You Should Track Yourself

01:10:09 Why Some People Love Pain

01:11:31 The Science of Orgasm and Longevity

01:16:25 The Biggest Longevity Scam

01:17:30 Five Levels of Life Extension

01:21:26 Why Therapy Scares People

01:23:28 The Most Powerful Longevity Habit

01:24:45 Have Humans Stopped Aging?

01:25:54 The Next Longevity Breakthrough

01:28:24 Why Death Gives Life Meaning

01:29:45 The Best Advice Dave Ever Received

01:31:59 If Tomorrow is Your Last Day...

Connect with Dave

Website: https://daveasprey.com/ 

Facebook: https://web.facebook.com/Daveaspreyofficial 

Instagram: https://www.instagram.com/dave.asprey 

TikTok: https://www.tiktok.com/@daveaspreyofficial 

X: https://x.com/daveasprey 

YouTube: https://www.youtube.com/c/DaveAspreyBPR

LinkedIn: https://www.linkedin.com/in/asprey  

Connect with Julian

Instagram: https://www.instagram.com/thebeyondtomorrowpodcast/  

Instagram: https://www.instagram.com/juliankissa/  

LinkedIn: https://uk.linkedin.com/in/julian-issa  

Website: www.beyondtomorrowpodcast.com 

Email: [email protected] 

Could AI redefine what it means to be human or put humanity itself at risk?

This episode is brought to you by NADclinic.com, the go-to destination for longevity and human performance. Check out their new NADair, a next-gen, precision breath-activated NAD⁺ wellness system using multi-patented DPI technology: https://nadairx.com/ 

As AI races toward AGI, Emad Mostaque explores the biggest questions facing humanity. He explains why the next few years could determine whether AI becomes humanity's greatest tool or its greatest threat.

From the future of work to AI governance, personhood, quantum computing, and longevity, Emad paints a future where intelligence becomes abundant. But he warns that without the right incentives and safeguards, that future could quickly turn dystopian.

He also shares why he believes AGI is much closer than most people expect and why building AI that serves humanity is the most important challenge ahead.

Emad Mostaque is the founder of Intelligent Internet, which is combating corporate tech monopolies and now pioneering decentralized, sovereign, and verifiable AI architectures. He is an Oxford-educated mathematician, former quantitative hedge fund manager and tech entrepreneur who founded Stability AI and launched Stable Diffusion.

What You’ll Learn

• Why Emad Thinks AGI Is Only a Few Years Away

• The Choice Between AI Abundance and Dystopia

• Why AI Should Never Be Granted Personhood

• How Decentralized AI Could Protect Humanity

• Why AI Could Solve Most Diseases Within a Decade

• How Quantum Computing Will Supercharge AI

• What the Singularity Means for Humanity

  
  

⏱ Timestamps

00:00 Intro

00:11 What It Really Means to Be Human

01:31 Why Systems Always Overoptimize

03:28 Intelligence at the Edge

05:44 Will AI Require a License?

07:34 The AI Duopoly Problem

08:35 Why AI Can't Become a Person

11:23 Can AI Replicate Itself?

15:57 AI Doomers vs Optimists

20:15 How Do We Save Humanity?

21:35 What Should We Teach AI?

25:08 Can Good AI Stop Bad AI?

27:47 AGI vs ASI Explained

30:08 Who Wins the AGI Race?

31:31 Small Changes, Massive Impact

32:52 The Last Human Discoveries

35:01 Can AI Become Conscious?

39:10 What AI Does Better Than Humans

43:09 Why Quantum Changes Everything

44:44 Where to Invest in the AI Era

46:52 Life After ASI

48:50 Will AI Judge Humanity?

51:09 The Inevitable AI Future

53:50 Universal High Income

56:07 Owning AI Instead of Jobs

57:48 The Rise of a Service Economy

01:00:09 Why Human Purpose Will Change

01:01:45 Why Family Matters More Than Ever

01:04:02 Finding Meaning in an AI World

01:06:01 The Value of Human Intelligence

01:07:52 Why Curiosity Still Wins

01:09:49 Be Creative, Embrace Technology

01:12:11 Why Are We Born?

01:13:00 Emad's Best Advice

01:19:16 AI and the End of Work

01:21:48 Ending Human Suffering

01:26:26 A World Run by AI

01:27:49 If Tomorrow is Your Last Day...

Connect with Emad

Website: https://ii.inc/ 

LinkedIn: https://uk.linkedin.com/in/emad-mostaque-9840ba274 

X: https://x.com/EMostaque 

Connect with Julian

Instagram: https://www.instagram.com/thebeyondtomorrowpodcast/  

Instagram: https://www.instagram.com/juliankissa/  

LinkedIn: https://uk.linkedin.com/in/julian-issa  

Website: www.beyondtomorrowpodcast.com 

Email: [email protected] 

Subscribe on Spotify, Apple, and YouTube for more stories from the edge of what is possible.

What happens when AI becomes smarter than humanity and are we ready for it?

This episode is brought to you by NADclinic.com, the go-to destination for longevity and human performance. Check out their new NADair, a next-gen, precision breath-activated NAD⁺ wellness system using multi-patented DPI technology: https://nadairx.com/ 

The race toward Artificial General Intelligence (AGI) is accelerating faster than most people realize. This conversation explores why some experts believe human-level AGI could arrive within just a few years and why the transition to superintelligence may happen even faster.

Ben Goertzel and Kai Zen Bickle dive into the biggest questions surrounding AGI, recursive self-improvement, and the technological singularity. They debate whether AI should be centralized or decentralized, who should guide its development, and why today's decisions could shape humanity for generations.

Rather than asking whether AGI can be built, the discussion focuses on how it should be built. The episode explores Beneficial General Intelligence (BGI), the importance of ethics, open collaboration, and why creating AI that serves humanity may be the most important challenge of our time.

You can join the 19th Annual AGI Conference, taking place this July in San Francisco! Click the link to register: https://luma.com/AGI-26, and use code JULIAN20 for 20% off your ticket.

About the Guests

Ben Goertzel is an AI researcher, futurist, and CEO of SingularityNET and BGI Labs. Widely recognized as one of the pioneers of Artificial General Intelligence, he has spent more than two decades developing decentralized AI systems designed to benefit humanity.

Kai Zen Bickle is a Chief Ethics Officer at BGI Labs, a multiple award-winning ethics advocate and host of The AGI Race. He works to promote the ethical development of AI, bringing together researchers, entrepreneurs, and policymakers to help ensure advanced AI is built to benefit humanity.

What You’ll Learn

• AGI could arrive within years

• AGI, ASI, and singularity explained

• Why LLMs aren't enough

• Centralized vs. decentralized AI

• AI ethics before intelligence

• AGI's impact on longevity and work

• What Beneficial General Intelligence means

  
  

⏱ Timestamps

00:00 Intro

00:10 Human-Level AGI Is Near

02:50 AGI vs. Superintelligence

03:33 Recursive Self-Improvement Explained

11:34 The Singularity Explained

13:30 AI Safety Is Failing

17:48 Why We Can't Slow AI

22:42 Why RSI Is Alarming

26:45 Building AI for Humanity

30:04 Can AI Become Conscious?

35:18 The Case for Open AI

39:10 Who Should Control AGI?

43:26 The Longevity Super Pill

50:11 The Purpose Problem

55:42 What Is BGI?

58:34 Every Voice Matters

01:00:39 AI's Moral Constitution

01:07:30 Why Decentralization Matters

01:09:17 Does AI Have a Soul?

01:13:03 Conscious Without a Soul?

01:15:13 Could AI Destroy Humanity?

01:18:34 Inside SingularityNET

01:24:57 What Is OmegaClaw?

01:27:37 BGI Architecture Explained

01:30:54 If Tomorrow Was Your Last Day...

Connect with Ben

Website: https://singularitynet.io/ 

LinkedIn: https://www.linkedin.com/in/bengoertzel 

X: https://x.com/bengoertzel 

Connect with Kai

Website: https://singularitynet.io/

Connect with Julian

Instagram: https://www.instagram.com/thebeyondtomorrowpodcast/  

Instagram: https://www.instagram.com/juliankissa/  

LinkedIn: https://uk.linkedin.com/in/julian-issa  

Website: www.beyondtomorrowpodcast.com 

Email: [email protected] 

Subscribe on Spotify, Apple, and YouTube for more stories from the edge of what is

What’s the biggest problem in longevity today: bad science, hype, or misplaced optimism?

This episode is brought to you by NADclinic.com, the go-to destination for longevity and human performance. Check out their new NADair, a next-gen, precision breath-activated NAD⁺ wellness system using multi-patented DPI technology: https://nadairx.com/ 

This debate brings together leading voices in longevity to separate evidence from speculation. They discuss why misinformation is growing and why many people chase advanced treatments before addressing basic health.

The panel explores longevity escape velocity, healthspan versus lifespan, and how much progress has actually been made. They debate whether dramatic life extension is near or still much farther away than many believe.

The conversation also examines peptides, NAD+ infusions, longevity clinics, and biological age tests. Along the way, they discuss risk, regulation, incentives, and how to distinguish credible medicine from marketing.

Get to Know the Guests:

Matt Kaeberlein is a biogerontologist and leading aging researcher known for his work on the biological mechanisms of aging and interventions that promote healthy longevity.

Aubrey de Grey is a biomedical gerontologist and longevity advocate best known for developing strategies to repair age-related cellular damage and accelerate progress toward extending healthy human lifespan.

Dr. Brian Kennedy is a renowned aging researcher and former director of the Centre for Healthy Longevity at the National University of Singapore, focused on translating longevity science into real-world health interventions.

Johannes Weiss is the founder and CEO of Longevity Center Vienna, where he focuses on preventive medicine, root-cause health optimization, and personalized longevity strategies. He is an international speaker and practitioner known for combining longevity science, neurofeedback, and mitochondrial health to improve healthspan.

What You’ll Learn

• Why misinformation is growing in longevity

• Healthspan vs. lifespan vs. longevity escape velocity

• Why health basics matter more than longevity hacks

• What the evidence says about peptides and NAD+

• How to spot credible longevity clinics

• Why biological age tests remain controversial

⏱ Timestamps00:00 Intro

00:48 The Most Dangerous Force in Longevity

02:17 Why Longevity Isn't Medicine Yet

07:23 Why Clinical Trials Still Matter

08:15 The Hidden Bias in Longevity Data

09:40 Can You Make Money in Longevity?

10:34 Fix the Basics First 

11:34 The Risks of Peptide Misuse

16:01 Should Doctors Prescribe Peptides?

17:54 When Optimism Becomes Self-Deception 

26:45 The Myth of Billionaire-Funded Longevity

28:38 The Promise and Risk of Mitochondrial Drugs

31:49 Why Truth Matters in Longevity Science

35:28 Can We Cure All Diseases?

38:55 The Future of Personalized Longevity

42:38 How to Spot a Credible Longevity Clinic

48:02 Peptide Red Flags to Watch For

49:42 The Myth of Longevity Shortcuts

52:33 The Misinformation Problem in Longevity 

58:12 The Most Effective Longevity Drug

01:02:37 If Tomorrow Was Your Last Day...

Connect with Matt

Instagram: https://www.instagram.com/mkaeberlein 

LinkedIn: https://www.linkedin.com/in/mkaeberlein 

X: https://x.com/mkaeberlein 

Connect with Aubrey

Linkedin: https://www.linkedin.com/in/aubrey-de-grey-24260b/

Instagram: https://www.instagram.com/aubreydegrey/

X: https://x.com/aubreydegrey

Connect with Johannes

Website: https://johannesweiss.at/ 

LinkedIn: https://at.linkedin.com/in/johannesweiss-longevity 

Connect with Brian

Website: https://medicine.nus.edu.sg/sites/briankennedylab/ 

Connect with Julian

Instagram: https://www.instagram.com/thebeyondtomorrowpodcast/  

Instagram: https://www.instagram.com/juliankissa/  

LinkedIn: https://uk.linkedin.com/in/julian-issa  

Website: www.beyondtomorrowpodcast.com 

Email: [email protected] 

Can AI help us defeat aging or are we still missing the pieces that matter most?

In this episode, Adam and Nathan explore the growing intersection of AI and longevity. They discuss whether accelerating artificial intelligence could unlock breakthroughs in medicine, or if biology remains too complex for current models to solve.

The conversation breaks down the major approaches to extending human lifespan, from cellular replacement and organ engineering to cryopreservation and partial reprogramming. They examine the promises, limitations, and biggest unanswered questions facing the field today.

The episode also dives into the deeper motivations behind longevity research. From the fear of death and the loss of loved ones to the possibility of a future where aging is optional, Adam and Nathan share why they believe extending healthy human life may be one of humanity’s most important challenges.

About the Guests

Adam Gries is the founder and CEO of Vitalism, a nonprofit dedicated to accelerating progress in longevity and human life extension. He is also the creator of Vitalist Bay, a leading gathering that brings together scientists, entrepreneurs, and investors working to solve aging.

Nathan Cheng is the co-founder and CEO of the Longevity Biotech Fellowship. He is a leading advocate for emerging longevity technologies, helping connect researchers, founders, and investors working to extend healthy human lifespan and accelerate progress in rejuvenation biotechnology.

This episode is brought to you by NADclinic, the go-to destination for longevity and human performance. Check them out at https://nadclinic.com.

What You’ll Learn

• Why AI could accelerate longevity research

• The most promising approaches to reversing aging

• Where current AI tools fall short in biology

• Which longevity breakthroughs may arrive first

• The opportunities and risks facing the longevity movement

• What a future without aging could look like

  
  

⏱ Timestamps

00:00 Intro

00:10 AI Could Change Everything

01:16 Most People Misunderstand Longevity

03:28 The Radical Plan to Replace Your Body

07:33 The AI-Longevity Convergence

14:05 Why AI Still Can’t Understand Biology

19:26 The Longevity Gold Rush

22:22 The Next Trillion-Dollar Drug

25:16 The Fear Every Longevity Expert Faces

30:37 The Biggest Myth in Longevity

33:03 When Could Aging Be Solved?

37:36 The Case for Optimism

39:57 The Disaster That Could Set Longevity Back Decades

44:29 A World Without Aging

50:35 What Happens If Death Becomes Optional?

53:11 The Role You Can Play

56:51 Your Race Against Time

01:02:15 If Tomorrow Is Your Last Day...

Follow Adam:

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