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Sharmin, Rabih, Reza, and Arsalan tackle a schema for glomerulonephritis
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Dr. Amara Finch presents a case of abdominal pain at VMR to Maani, Maria, Anna and Smitha.
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Dr. Amara Finch
Originally from Atlanta, Georgia, Amara spent time in Massachusetts, Vermont, British Columbia, Connecticut and Colorado before returning to the vibrant ATL for medical school. She is now an intern in the Med-Peds program at the University of Arizona in Phoenix. She is passionate about better understanding the relationship between early life exposures and lifelong health as a means to improve preventive medicine for kiddos, re-imagine our approach to adult disease, and disrupt intergenerational cycles of health inequity. Outside of the hospital you can find her hiking, biking, writing, and working on her collection of fermented foods including kimchi and hot sauce.
Steph presents a case of pleuritic chest pain to Dan and Jack
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Malika presents a Human Dx case of pleuritic chest pain to Lindsey, Aaron, and Kelly
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Dr. Kelly Uelmen
Kelly is a second-year internal medicine resident at Mercy Health in Muskegon, MI. I’m from Wisconsin and went to medical school at LMU-DCOM in Tennessee. I am looking forward to a career in hospitalist medicine once I finish residency. In my free time, I enjoy traveling (pre-COVID, anyway), cooking, reading fiction, and playing with my dog, Bubba.
Dr. Aaron Sabal
Aaron is currently a PGY-3 at Mercy Health Muskegon aspiring for a career in hospital medicine. He was born and raised in Westland, MI (Detroit metro area) and went to Wayne State University for his undergraduate studies thinking he would be a physical therapist, massage therapist, and dietitian (yes, all three of those). However, one week prior to starting a massage therapy program, he had an epiphany and decided to go to medical school instead. He was fortunate to be accepted at MSUCOM and fell in love with Internal Medicine. His passions include all things medical. In particular, he is passionate about medical education, how best to help physicians learn, diagnostic reasoning, and creating an environment of learning where no one is afraid to express what they’re thinking. When he is not pursuing his love of learning, he is spending time with his wife and their boys (2 cats and a dog), playing with his animals, preparing to be a father to his soon-to-be-born son, crossfitting, doing DIY home-improvement projects, exploring national parks, or reading good nonmedical fiction with a cat or dog in his lap begging for his love and attention.
Malika Gill
Malika Gill is a 4th-year medical student at Virginia Commonwealth University pursuing internal medicine with interests in gastroenterology and medical education. She completed her undergraduate studies in biology and psychology at Virginia Commonwealth University. In her free time, she loves to read, try new restaurants, and spend time with friends and family.
This is the second episode of a three-part series on understanding and dismantling race-based medicine. We invite Drs. Nwamaka Eneanya and Jennifer Tsai to discuss the limitations and harms of race-based medicine in clinical practice. Our guests explain how we can incorporate race-conscious medicine in clinical settings, medical education, and biomedical/epidemiological research to responsibly recognize and address the harms of racial inequality.
Learning Objectives
After listening to this episode learners will be able to…
Credits
Download Transcript Here
Episode 4 – Race-Based Medicine, Part 2: Clinical Perspectives
Show Notes
Naomi F. Fields
Time Stamps
00:00 Mission, vision, and introductions of hosts
01:30 Background on three-episode series
02:26 Introductions of guests
04:16 How Dr. Eneanya has seen race-based medicine play out in clinical practice
07:19 How Dr. Tsai has seen race-based medicine play out in clinical practice
10:45 What role should race play in making clinical decisions?
13:16 Status of the current conversation on removing race from eGFR calculators: why is it so contentious?
19:05 Clarifying the “ethics vs science” argument and critiquing research techniques
22:00 Resurgence of race-based speculation in COVID-19-related research
25:57 Implantation of ideas about innate racial inferiority within medicine
28:32 Will removal of race from algorithms potentially harm our patients?
33:19 Danger of normalizing immutable, innate racial difference within clinical algorithms
38:10 What role should race hold as we move toward health equity?
45:50 Key takeaways for trainees
47:45 Key takeaways for faculty
49:17 Pointers to those interested in health equity research
50:17 One thing you can employ in your practice today
54:14 Bloopers!
Episode Takeaways:
Trainees
Asking thoughtful questions that challenge the “status quo” can prove an effective means of sparking discussions while minimizing the potential for negative retaliation. Dr. Tsai describes previously asking her attendings, “Why is there a race correction for adults in nephrology, but not for children? What happens at age 18 [to provoke the need for correction]?” Questions such as these can stimulate thoughtful inquiry and remind all of us of the responsibility to be critical practitioners.
Faculty
If you feel your cause is important, keep going — even when you are challenged by others. Attending physicians have tremendous power in dictating culture, and are so valuable in extending this work, especially given how the hierarchical nature of medicine can make it difficult for trainees to advocate firmly. Moreover, center patients not only in discussions about individual decision-making but in constructing and drawing meaning from the research.
All
If you are interested in health equity, recognize that there is a breadth of research established in the fields of health equity, disparities, and structural racism. Be sure to do the work to educate yourself about the foundations of this work, and collaborate with those who have been studying and establishing it if you have the opportunity.
Poet Marge Piercy has written, “The work of the world is as common as mud.” While there indubitably exists a need to advance scholarship and theory, we must also ground ourselves in the day-to-day actions that can bring comfort and kindness to our patients. Where can you give an extra inch to those for whom you are caring?
Pearls
Role of Race in Clinical Reasoning
Harnessing the idea that “race is a social construct” to exclude consideration of race from medicine altogether does a disservice to our patients. Race, racism, and racial inequality have tangible impacts on people’s livelihoods, much less their experiences in the healthcare system. For instance, there is well-established research on how the stress of racism and racial inequality become “embodied” by modifying people’s cortisol levels to exert end-organ effects. Thinking about race is not racist in and of itself: It is the usage of race in the service of white supremacy or oppression that makes that transformation. Being race-conscious, or critically curious about the ways in which racism and racial inequality may affect our patients, can actually offer a starting point for advancing health justice. Much is akin to how naming the “battered child syndrome” catalyzed changes in our frameworks for addressing child abuse, critical curiosity in the space of racism can help us to develop thoughtful plans for tracking, discussing, and monitoring racism within in healthcare settings and beyond.
Race in eGFR Calculations — Why So Contentious?
eGFR equation-building is a complex science. Returning to the early literature that informs the equations reminds us that this research demonstrated racially stratified differences between Black and white cohorts. However, these studies did not account for many of the factors that can impact creatinine, the main biomarker used in eGFR calculations. These factors include a high-protein diet, muscle mass, creatinine generation, and certain medications. Many of the Black participants in the CKD epi study came from an African-American cohort (ASK trial) in which 50% of participants hadn’t graduated high school and over 50% made less than $50,000/year. These factors may have impacted their diet, physical activity, and medications, thus impacting their creatinine levels and the inputs that we use for GFR. This reminds us that using race as a catch-all can shroud other factors (ex. structural racism) that more rigorously account for differences observed between groups. And, as we think about revamping eGFR calculators, we must also ensure that there are standardized means of doing so across institutions.
Ethics-Plus: Reforming our Approaches to Clinical Research
Without question, there exists a strong ethical imperative to eradicate racism from biomedical science and to better use biomedical science in the service of health justice. There also exists an imperative to refine how we use race in research, given the scientific evidence that it is a social construct. Critiquing the cursory usage of race in studies illuminates the need to clearly define and standardize race as an operational variable, explain that to which racial differences are attributed, and describe how we interpolate meaning from these differences. Failing to do so may obfuscate the realities of social-structural racism, and obscure opportunities for improving understanding or intervention. Rigorous usage of race is not only ethically sound: it’s also better science.
In this vein, our researchers can take advantage of the technology that we have to ask more sophisticated questions that generate true accuracy, rather than those that simply accept race as a surrogate. We might critically think about why we might use race in a regression model, and proactively consider how we will interpret and responsibly discuss findings that may result. We might group people across socio-demographic categories (ex. education, income, number of previous hospitalizations) that also lead to clinical outcomes, not only race-based stratification. When racial differences are observed, we might further examine contributors to outcomes within a group. Our journals can help lead the charge by more diligently enforcing fastidious usage of race within papers they choose to publish. Rather than accepting racially-stratified differences in outcomes as inexorable and without further inquiry, we can seek to understand and address what underpins these phenomena. Consensus standards that guide authors on ethical use of race in scientific research exist. Our esteemed publications should ensure that investigations that utilize racial variables follow these guidelines before being published.
Addressing Potential Harms of Removal of Race from Clinical Calculators
Some have expressed fear that removing race from eGFR calculators will result in inaccurate therapeutic changes (ex. premature dialysis initiation, premature renal transplants, or inappropriate medication administration) that will primarily affect Black patients. However, the diagnostic approach used to determine changes in clinical management of renal disease (i.e. dialysis, transplant) is multifactorial; it is not based on eGFR alone. Additionally, research has shown that using symptom-prompted modifications to management, in the context of shared decision-making, can improve outcomes. Using the eGFR calculators as a sole determinant offers a limited metric with a ~30% margin of error. We can and should be incorporating other methods of evaluating kidney function (ex. 24-h Cr clearance, cystatin C) within a body of data. This can contribute to a more holistic understanding of disease progression and management.
How Bearing the Burden of Change Reinforces Racism
Some responses to the prospect of eliminating race corrections have asked proponents of these changes to prove that removing race corrections will not do harm to patients. In juxtaposition, research that established the corrections was not necessarily asked to prove that corrections are harmless. The additional evidence and surveillance needed to demonstrate the limited relevance of race belies a collective investment in the immutability of biological racial difference. However, race corrections do in fact cause both ideological and tangible harm in that they reify essential biological racial differences. Social psychology research demonstrates that when race is given this genetic basis, trainees display more apathy toward racial outgroups and a tendency to consider their physiology as innately dysfunctional. As a result, they demonstrate lower levels of accountability to creatively problem-solve for patients of color. It is also the case that many of these race corrections (eGFR, ASCVD, UTI, VBAC) about which people have been protective have not actually shown benefit to people of color.
Links
References discussed throughout episode
Additional references and papers as mentioned in the episode
Disclosures
Mr. Khazanchi is a member of the American Medical Association’s Council on Medical Education, but the views presented herein represent his own and not necessarily those of the AMA or the Council. Dr. Eneanya is a member of the National Kidney Foundation and the American Society of Nephrology Task Force; the views herein represent her own and not necessarily those of the NKF or the Task Force. The hosts and guests report no other relevant financial disclosures.
Citation
Eneanya A, Tsai J, Williams J, Essien UR, Paul D, Fields NF, Nolen L, Ogunwole M, Onuoha C, Khazanchi R. “Episode 4: Dismantling Race-Based Medicine, Part 2: Clinical Perspectives.” The Clinical Problem Solvers Podcast. https://clinicalproblemsolving.com/episodes December 17, 2020.
https://clinicalproblemsolving.com/wp-content/uploads/2020/12/Meningoencephalitis-Schema-BeaST-Mode-Edition_FINAL-online-audio-converter.com_.mp3
Reza, Rabih, Sharmin, and Arsalan break down meningoencephalitis in this bite sized schema episode, inspired by Dr. Kimberly Manning.
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Dhruv and Travis present a case of R sided weakness and numbness to Kiara, Tahir, and Aaron, as we continue our campaign to end neurophobia!
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Dhruv Srinivasachar
Dhruv Srinivasachar is a 4th year medical student at Virginia Commonwealth University School of Medicine (the Medical College of Virginia for all the veteran attendings out there). Introduced to medicine through research, Dhruv has shifted his passions to empathetic clinical care and medical education, as a contributor to the CPSolvers (especially through VMR as a case presenter, discussant, and compiler of cases) and team member for the Not Just Little Adults podcast (CPedsSolvers, if you will). When he’s not interviewing for Med-Peds residency, he can be found biking around Richmond, VA, gardening, and cooking.
Tahir Malik
Tahir Malik is a 4th-year medical student at Baylor College of Medicine interested in artificial intelligence, cardiology, and global health. He is interested in performing healthcare disparities research, in capacity-building in low-resource settings, and in understanding the role AI might play in global health solutions. In his free time, Tahir is an avid runner and biker and is trying to become a reasonable cook.
Travis Smith
Dr. Smith is a student educator and community EM physician currently practicing in Jacksonville, Florida. He currently is an Associate Professor of Emergency Medicine, Assistant Dean of Clinical Education, and the Director of the Clinical Clerkship Curriculum for LECOM. He attended undergrad at FSU where he received his bachelor’s degree in Biological Science. He then attended Lake Erie College of Osteopathic Medicine in Bradenton for his medical degree and then completed his residency in emergency medicine at the University of Florida Jacksonville campus. He has been board-certified in emergency medicine through ABEM since 2013. In his free time, he serves as the lead section editor for the Human dx project as well as a frequent contributor to the Clinical Problem Solvers and is heavily involved in #Medtwitter running the @medtweetorials account as well as his own @RosenelliEM
https://clinicalproblemsolving.com/wp-content/uploads/2020/12/ARM-EP-3-Structural-Inequities-and-the-Pandemics-Winter-Surge-1.mp3
In this episode of Clinical Problem Solvers: Anti-Racism in Medicine, we sit down with Ed Yong, an award-winning journalist and science writer with The Atlantic, to discuss the structural inequities amplified by COVID-19 as well as the social concerns associated with the impending/present second wave of the pandemic.
Learning Objectives
After listening to this episode listeners will be able to…
Credits
Clinical Problem Solvers: Anti-Racism in Medicine
Show Notes – Episode 3: Structural Inequities and the Pandemic’s Winter Surge
December 3rd, 2020
By: Chioma Onuoha
Timestamps
00:00 Music/Intro
00:20 Mission and Vision
00:32 Introduction of Ed Yong
02:00 Disproportionate impact of COVID-19 on minority communities
04:00 Racism in the national/policy response to COVID-19
07:00 Health Care Worker Fatigue
09:30 Grief and the Unique Frustrations of Health Care Workers of Color
11:30 The “Chinese” Virus and the history of the pandemic
14:00 Administrative Blame Shifting
17:00 How Could This Have Been Prevented?
20:00 COVID-19 and indigenous populations
Takeaways
Currently in the COVID-19 pandemic, social interventions are the only interventions available to us. When it comes to pandemics more broadly, the role of non-pharmaceutical interventions, like mask wearing, social distancing, and stay at home orders, must be recognized for their robust potential to reduce disease spread and burden. (Reflection Question: How can I best communicate the importance of social interventions to my extended family, community, and patients?)
It is dangerous to look at the racial and ethnic health disparities highlighted by COVID-19 and attribute them to biological differences*. Many of the populations who suffer from these disparities also suffer from structural inequity and historical discrimination which impact their quality of life and health outcomes. Marginalized communities have historically received the brunt of the blame when it comes to widespread pandemics without recognition of the role that structural factors play in creating and maintaining health inequity.
*To learn more about the danger of biological explanations for health disparities see the CPS Anti-Racism in Medicine three-part episode series Dismantling Race-Based Medicine. Part 1: Historical & Ethical Perspectives featuring Professor Edwin Lindo is available now.
Inequities worsen if they are not specifically addressed in policy. Without intentional effort put into addressing the root cause of structural inequities, it is possible that interventions will cause more harm than good. (Reflection Question: How should the concept of equity vs. equity be applied in creation of health policy?)
Pearls
The disparities amplified by COVID-19 are not new or unsurprising
The narrative of COVID-19 being a “ great equalizer” is largely untrue. If anything, COVID-19 has removed “the veil” and made the extent of the inequities in this country very clear. Marginalized communities are especially vulnerable to COVID-19 due to structural factors like segregation, lack of access to clean water, poor air quality, and limited availability of health care. These structural inequities are longstanding and will require long-lasting and intentional rectification.
Frontline Workers Pushed to their Limits
Touching accounts from frontline workers, in particular, nurses, who are uniquely positioned to face the devastating impacts of the disease, have clarified the toll that COVID-19 has placed on care workers. The emotional and physical fatigue associated with such immense loss of human life is leading to burnout among the very group that is required to address this disease. For many health care workers of color, their struggles are compounded by personal grief and increased expectations to lead anti-racism efforts within institutional walls.
Blame shifting
During COVID-19, we have seen marginalized communities be positioned as scapegoats to explain the prevalence and persistence of the disease. This is not a new phenomenon. Ed Yong cites anti-Blackness during the Ebola outbreak; homophobia, transphobia, and condemnation of sex workers and people who use drugs during the HIV epidemic; and current anti-asian rhetoric during COVID-19 and the original SARS as examples. Blame is deflected to populations on the outskirts of society and used as justification to delay or fail to provide aid. Throughout the duration of the pandemic, we have seen the nature of this blame evolve. While it started with accusations that Black people and POC do not take the virus seriously and/or have chronic diseases and unhealthy habits, most presently it manifests through discourse around black people’s weariness of taking the forthcoming COVID-19 vaccine. Rather than placing blame on marginalized populations, it is crucial that we first analyze history and external influences that may explain the behaviors and outcomes being observed.
Overreliance on Biomedical Measures
“[Rudolf Virchow] specifically writes ‘Medicine is a social science’ and we have lost that understanding” – Ed Yong
For much of the COVID-19 pandemic, rhetoric in the United States has centered around waiting for biochemical and pharmaceutical interventions to be developed rather than fully taking advantage of the social interventions currently available. Social interventions are powerful, and as we can see from the COVID-19 responses of countries like South Korea and Taiwan, they are effective at managing this disease. This reality highlights the importance of sociological and anthropological expertise in medicine and the need to expand interdisciplinary exchange in health care more broadly.
References Discussed in Episode
01:30
Yong, E. (2020, September 20). How Pandemic Defeated America. The Atlantic. https://www.theatlantic.com/magazine/archive/2020/09/coronavirus-american-failure/614191/
04:00
Serwer, A. (2020, May 8). The Coronavirus Was an Emergency Until Trump Found Out Who Was Dying, The Atlantic. https://www.theatlantic.com/ideas/archive/2020/05/americas-racial-contract-showing/611389/
Kendi, I. X. (2020, April 6). What the Racial Data Show. The Atlantic. https://www.theatlantic.com/ideas/archive/2020/04/coronavirus-exposing-our-racial-divides/609526/
05:50
APM Research Lab Staff. (2020, November 12). The Color of the Coronavirus: COVID-19 Deaths by Race and Ethnicity in the U.S. APM Research Lab. https://www.apmresearchlab.org/covid/deaths-by-race
07:00
Yong, E. (2020, November 13). No One Is Listening to US. The Atlantic. https://www.theatlantic.com/health/archive/2020/11/third-surge-breaking-healthcare-workers/617091/
Yong, E. (2020, November 20). Hospitals Know What’s Coming. The Atlantic.
https://www.theatlantic.com/health/archive/2020/11/americas-best-prepared-hospital-nearly-overwhelmed/617156/
Yong, E. (2020, July 7). The Pandemic Experts Are Not Okay. The Atlantic. https://www.theatlantic.com/health/archive/2020/07/pandemic-experts-are-not-okay/613879/
10:30
Dr. Uche Blackstock (@uche_blackstock)
Dr. Esther Choo (@choo_ek)
19:00
Rashawn, R. (2020, April 9). Why are Blacks dying at higher rates from COVID-19?. Brookings. https://www.brookings.edu/blog/fixgov/2020/04/09/why-are-blacks-dying-at-higher-rates-from-covid-19/
Hernandez, E. (2020, April 23). Inequities in COVID-19 are tragic but preventable. The Hill. https://thehill.com/blogs/congress-blog/healthcare/494251-inequities-in-covid-19-are-tragic-but-preventable#bottom-story-socials
20:00
McFarling, U.L. (2020, November 17). ‘They’ve been following the science’: How the Covid-19 pandemic has been curtailed in the Cherokee Nation. STAT. https://www.statnews.com/2020/11/17/how-covid19-has-been-curtailed-in-cherokee-nation/
Additional References
Disclosures
The hosts and guests report no relevant financial disclosures.
Citation
Yong E, Essien UR, Nolen L, Khazanchi, R, Ogunwole M, Fields N, Onuoha C, Williams J, , Paul D. “Episode 4: Structural Inequalities and a Second Wave.” The Clinical Problem Solvers Podcast. https://clinicalproblemsolving.com/episodes. December 3, 2020.
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Kushal presents a Human Dx unknown to Jack, Kushal, Gabe, and Jake.
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Schema 1
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Kushal Vaishani
Kushal is a hospitalist and contributing editor for the Adult Medicine section at Human Dx. After finishing his medical school in India, he completed his residency training at Brandon Regional Hospital and LSUHSC – University Hospital and Clinics. His academic interests include clinical reasoning, medical education, high-value care, and infectious diseases.
Gabe Siegel
Gabe Siegel is currently a PGY-1 Emergency Medicine Resident at Denver Health. Gabe completed medical school at Rush Medical College in Chicago, IL. When not working, he is busy enjoying the outdoors in Colorado and hunting for good food in Denver. His academic interests include health policy, critical care, and social EM.
Jake Hershey
Jake is currently a PGY-1 in the IM hospital training track at the University of Colorado and graduated from Rush Medical College alongside his friend and co-discussant Gabe. His passions in medicine include medical education, clinical reasoning, and after-work commiseration with his co-residents. In his free time, he loves exploring the Colorado wilderness to experience the amazing hiking, kayaking, and snowboarding that the state has to offer.
Dr. John Alexander presents a Human Dx unknown to Dr. Courtney Wagner, Dr. Ryan Goetz, and Dan
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Courtney Wagner
Courtney Wagner is PGY-2 in Internal Medicine resident at the University of Alabama at Birmingham. She is a Florida native and grew up in and around the water either swimming competitively, SCUBA diving, or fishing. She initially graduated from the University of Central Florida with a biological sciences degree and taught high school science before going back to school for nursing at the University of South Florida. After gaining experience at the bedside as an ICU nurse, she pursued a career in medicine by returning to UCF for medical school. Currently interested in academic medicine with a heart for hospice and palliative and the geriatric population. She loves cooking, hiking, and triathlons, having completed over 60 races, including Ironman Cozumel.
John Alexander
John Alexander is a PGY-2 internal medicine resident at the University of Tennessee Health Science Center in Memphis. He got his undergraduate degree in history from Rhodes College and graduated from William Carey University College of Osteopathic Medicine. His research interests include clinical and diagnostic reasoning and cardiology. He hopes to pursue a career in academic medicine. Outside of the hospital he enjoys playing tennis, traveling, and spending time with family and friends.
Ryan Goetz
Ryan Goetz is a second-year internal medicine resident at the University of Alabama Birmingham. He attended medical school at the Medical College of Georgia. He wants to pursue a career in pulmonary/critical care medicine after completing his residency. His clinical/research interests include ventilator physiology/teaching, clinical reasoning, bronchiectasis, and ARDS. In his spare time, Ryan enjoys Orange Theory Fitness workouts, craft beer, and history podcasts.
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