Can you beat the so-called 'curse' of the child performer? Maryam Maruf brings together two women who grew up on camera - the American star of the films Matilda and Mrs Doubtfire, and a South African youth TV presenter.

At six years old Mara Wilson was playing Robin Williams's daughter in Mrs Doubtfire, then she bagged the leading role in the film version of Roald Dahl's Matilda. For a few years she was the cutest little girl in Hollywood. Then as she hit puberty and did not become classically 'pretty', she discovered that the parts simply dried up. Mara chose not to re-enter the limelight as an adult, and is a writer and storyteller in New York. She's written a memoir called 'Where Am I Now?'

Mandisa Nakana Taylor shot to fame in South Africa aged 10, as one of a multi-racial cast of young presenters on the kids' show YOTV. For six years children raced home after school and watched her grow up on their televisions. Mandisa says it was great fun, and there were a lot of first kisses on set, but they were also expected to maintain an adult work ethic. Now a mother and student in the UK, she still appears on screen, this time on her own YouTube channel.

(Photo: (L) Mandisa Nakana Taylor. Credit: Vanity Studios. (R) Mara Wilson. Credit: Ari Scott)

How do you feel about graffiti and street art? Is it a democratic form of creative expression, or an eyesore, a public nuisance, that gets your blood boiling? These are questions that Kim Chakanetsa puts to her two guests today.

Olga Alexopoulou lives in Turkey but is originally from Greece. She has a master's degree in Fine Art from Oxford University but she likes to paint on walls, big walls. She is responsible for the biggest mural in Greece, all 350 square metres of it. Street art has been very visible during the recent crises in both Turkey and Greece and while Olga's work promotes peace she has also had to face down her critics.

Lady Pink has been described as "the first lady of graffiti". She was born in Ecuador but made a name for herself across New York by literally spray painting her name on the city's subway trains. She was one of very few women on the scene in the late '70s. She used to dress as a boy to avoid unwanted attention. Three decades on, she is now one of the leading figures in the street art scene.

(Photo: Olga Alexopoulou (L). Credit: Yannis Bournias. (R) Lady Pink. Credit: Lauren Thomas)

When you are involved in the race to shed light on some of our biggest scientific questions, does your gender matter? Kim Chakanetsa brings together two successful female life scientists at the new world-leading Crick Institute in London. They are both leading ground-breaking research in their respective fields, and are joined by young women from Camden School for Girls who are considering a career in science.

Dr Vivian Li grew up in Hong Kong and completed her PhD there, and says it was only when she went on to conduct research in Europe that she noticed any gender divide in science. She found that male colleagues did not take her expertise seriously as a young woman, and so she had to work twice as hard to prove herself. Vivian now leads a molecular biotechnology research team, and is pioneering a technique to create human intestines in the lab, to then transplant back into patients. She says she used to work seven days a week, but since having a family she has learnt to prioritise her work differently and get her weekends back.

British virologist Dr Kate Bishop's research focuses on HIV and other retro-viruses, and she hopes her work could contribute to stopping HIV in its tracks at an earlier stage. Kate was the first in her family to go to university, and says she was always encouraged by her parents, who never put boundaries on her ambition. Leading a research group means she is less likely to be sitting at the bench conducting an experiment herself, but she now gets the satisfaction of passing her knowledge on to the next generation of scientists.

(Photo: The Conversation team and guests at The Crick Institute, London)

Kim Chakanetsa is in candid and intimate conversation with two women who have made the life altering decision to enter a religious order.

Mother Hildegarde is a nun in a silent, cloistered Catholic convent that overlooks London's Hyde Park. Originally from Australia, she entered religious life at 35, giving up her family, friends and name. She says she wanted to wear a habit, but found obeying the monastic 'rule' very hard to begin with, and as a self-confessed chatterbox she also really struggled with not talking! Fifteen years on she is comfortable leading a life spent in prayer and contemplation, and says although this life involves sacrifice, it is worth it.

Sister Tracy Kemme is 30 and took 'first vows' with the Sisters of Charity of Cincinnati in the US last year. Tracy made the heart-wrenching decision to break up with the love of her life to pursue her vocation, because even though he was everything she wanted, she realised that still was not enough for her. She says that society portrays religious life as giving up a lot of things. "I think people have unease with the fact that we don't have sex. We take a vow of celibacy, we take a vow of poverty and a vow of obedience and that's pretty counter cultural. But who would do that if that's what it's really all about?".

(Photo: Mother Hildegarde (L) and (R) Sister Tracy Kemme)

Siphokazi Mdlankomo comes from South Africa and Marissa Begonia from the Philippines but they have plenty in common. They have both dedicated a great deal of their lives to taking care of other people's households and children. They are Kim Chakanetsa's guests on this programme and they are discussing life as a domestic worker.

Marissa Begonia left her three young children to work overseas. It was a tough decision for her but she couldn't bear to see them going hungry at home in the Philippines. She found work initially in Hong Kong and then Singapore and finally London. Her choice has worked out for her, after years of providing for her children back home, she was finally able to bring them to join her in London. But the separation has taken its toll on all of them, and so has the work. Melissa has seen and heard of so much mistreatment among domestic workers that she decided to set up an organisation to protect the rights and welfare of others in her profession. The organisation is called Justice for Domestic Workers.

Until very recently Siphokazi Mdlankomo was working for a family in Johannesburg, South Africa but she's had to leave her job to focus full time on her new role on television and writing cookery books. She came to fame when she was runner-up in the South African reality TV show Master Chef. Her cooking has come a long way since she started her working life. She looks back fondly at the young Siphokazi, just starting out in her career, back then, she didn't know what garlic was, or fresh herbs or how to make a piece of toast.

Siphokazi and Marissa share their intimate, moving and sometimes funny stories of running someone else's household.

(Photo: Marissa Begonia (L) and (R) Siphokazi Mdlankomo)

Growing up in Santiago Melissa Aldana learnt to play the tenor saxophone or 'horn' at her father's knee, though he took some convincing that she would stick with it. She did, and went on to become the first ever female instrumentalist to win the prestigious Thelonious Monk Jazz Award in 2013. Melissa is now the leader of a successful jazz trio based in New York, and loves her work, but is concerned that a musician's life on the road will be hard to square with starting a family when the time comes.

South African musician Nomfundo Xaluva is winning awards for putting a new twist on her country's very strong jazz tradition. As well as singing and composing, Nomfundo says she is one of very few female black pianists in South Africa, and so feels responsible for being a role model to young girls. Being Xhosa, from the Eastern Cape, music forms a huge part of her culture, and she tries to incorporate this into her work, often singing in her mother tongue. Nomfundo reckons jazz is slowly becoming hip again, and she is excited to be a part of that.

L-Photo: Melissa Aldana.

Kim Chakanetsa meets two women who are taking on the challenge of combating bullying in Pakistan and the US.

Zainab Chughtai says the bullying she endured as a young girl inspired her to go into schools to try and stop other school children experiencing what she did. The emotional impact was so severe on Zainab, she says it's affected her personal relationships as an adult. Her campaign, Bully Proof, travels across Pakistan providing workshops to school children which create a safe space for them to open up about bullying - whether they are the victim, or the perpetrator.

Lauren Paul was the target of bullying by a group of girls at school in California. It was so traumatic it led to depression, an eating disorder and even an attempt to take her own life. She says every single woman can recall a moment when their relationship with other girls had a negative effect on them. This is why she co-founded 'Kind Campaign', an organisation which goes into schools across the US working with girls of all ages in the hopes of spreading a positive message, and stamping out girl-against-girl bullying.

(Photo: Left to right, Zainab Chughtai. Credit: Hamza Bajwa. Lauren Paul. Credit: Brandon Kidd)

Sapna Bhavnani is one of India's most celebrated hair stylists and is known for her own cropped hair and tattoos. Her Mumbai based salon, Mad-O-Wat, is the go-to place for Bollywood's A-list when their hair needs some attention. Clients include actors, politicians and sports stars like Indian cricket captain Mahendra Singh Dhoni. Sapna says her hair appointments can often turn into therapy sessions as her clients want to get their problems off their chest when they're sitting in her chair.

Charlotte Mensah developed a passion for hair styling while she looked after her little sister's hair after their mother died. Charlotte, who has twice been named British Afro Hairdresser of the Year, (by the British Hairdressing Awards) grew up in Ghana and moved to London when she was 11 years old. She goes back and forth to Accra and says it gives her a lot of inspiration for the styles she creates in the Hair Lounge, her Portobello Road salon, which specialises in afro hair. Charlotte promotes natural hair and says women are embracing this look.

Photo: (L)-Sapna Bhavnani. Credit: Sheetal Sherekar.

Two women whose aim is to make sex work safer in Uganda and New Zealand join Kim Chakanetsa to exchange experiences.

Daisy Nakato is the founder of WONETHA, a sex workers' rights and support organisation in Kampala, Uganda. She says she chose to go into sex work at 17, but did face many challenges including violence from clients and running from the police. She is now building a better relationship with the police, which she hopes will lead to a reduction in violence against sex workers, but for her decriminalisation is the ultimate goal. Daisy is also HIV positive, and her project encourages sex workers to get tested and then supports them in controlling the spread of the disease.

New Zealander Catherine Healy went from teaching in a school to sex work in a massage parlour in her thirties. She says this was an empowering choice for her, but she was appalled at the lack of any protections for her profession, which was then illegal. So she formed the New Zealand Prostitutes Collective and led a long campaign to decriminalise all forms of sex work. This law was passed in 2003 and gives full employment rights to sex workers, and Catherine says the police are now partners in keeping sex workers safe.

Kim Chakanetsa gets into the driving seat with two female truckers from Sweden and Australia.

Elin Engstrom test drives heavy haulage trucks for Swedish transport company Scania. The 26

Heather Jones is from western Australia and runs Pilbara Heavy Haulage Girls, which trains women to handle big trucks. She has worked in this industry for 25 years and got into it because as a single parent she needed a job where she could take her two little girls along with her. She describes the trucking industry in Australia like a big family, but even though it is welcoming, Heather says women have to work 200% to prove themselves. She can drive up to 17 hours per day, in trucks that are up to 60 metres. In summer it can reach 55 degrees and Heather says melting tarmac can be tough to deal with.

(Photo: Elin Engstrom (L) and Heather Jones)