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HEALTH NEWS
Vitamin K protects cells3 grams of fresh salmon does wonders for high blood pressure, study revealsPhysical activity stimulates the generation of new heart muscle cells in aged miceThe Human Mind Is Not Meant to Be Awake After Midnight, Scientists WarnSocial Isolation, Loneliness Raise Risk Of Death From Heart Attack Or Stroke By Nearly A ThirdMushrooms of the Far East hold promise for the anti-cancer therapy
Vitamin K protects cells
Helmholtz Zentrum München (Germany), August 5 2022
An article appearing in Nature reported that the reduced form of vitamin K has an antioxidant effect that inhibits cell death caused by ferroptosis: an iron-dependent type of programmed cell death characterized by the oxidative destruction of cell membranes. “We identified that vitamin K, including phylloquinone (vitamin K1) and menaquinone-4 (vitamin K2), is able to efficiently rescue cells and tissues from undergoing ferroptosis,” first author Eikan Mishima announced.
Ferroptosis has been implicated in Alzheimer disease and other disorders. “Ferroptosis, a non-apoptotic form of cell death marked by iron-dependent lipid peroxidation, has a key role in organ injury, degenerative disease and vulnerability of therapy-resistant cancers,” the authors explained. “Here we show that the fully reduced forms of vitamin K—a group of naphthoquinones that includes menaquinone and phylloquinone—confer a strong anti-ferroptotic function, in addition to the conventional function linked to blood clotting.”
In the current investigation, they determined that the fully reduced form of vitamin K (vitamin K hydroquinone) is a strong antioxidant and prevents ferroptosis. “The reduced forms of Vitamin K and coenzyme Q10 are not very stable, so our finding that FSP1 can maintain them in their active (reduced) state is key to understanding how they are able to function to maintain cell viability,” coauthor Derek A. Pratt stated.
The team found that vitamin E and three forms of vitamin K— phylloquinone, menaquinone-4 (MK4) and menadione (vitamin K3)—rescued cells that were genetically modified to undergo ferroptosis.
3 grams of fresh salmon does wonders for high blood pressure, study reveals
Macau University of Science and Technology (China), August 9, 2022
Omega-3 carries many health benefits, and a new review suggests eating three grams of it per day is enough to lower your blood pressure. The findings include omega-3 fatty acids obtained from food or dietary supplements.
“According to our research, the average adult may have a modest blood pressure reduction from consuming about 3 grams a day of these fatty acids,” says Xinzhi Li, MD, PhD, assistant professor and program director of the School of Pharmacy at Macau University of Science and Technology in China.
The average fish oil supplement carries an average of 300 mg of omega-3 per pill. A four to five-ounce Atlantic salmon carries about three grams of omega-3 fatty acids.
“Most of the studies reported on fish oil supplements rather than on EPA and DHA omega-3s consumed in food, which suggests supplements may be an alternative for those who cannot eat fatty fish such as salmon regularly,” explains Dr. Li. “Algae supplements with EPA and DHA fatty acids are also an option for people who do not consume fish or other animal products.”
The National Institutes of Health recommends 1.1 to 1.6 grams of omega-3 fatty acids daily. The American Heart Association advises getting some of your omega-3 intake through two servings of three to four ounces of cooked fish per week.
The review combed through the data from 71 clinical trials studying the relationship between blood pressure and the omega-3 fatty acids DHA and EPA in adults with or without high blood pressure or chole