In this episode, Dr. Anthony Carnicelli sits down with Dr. Ryan Tedford, a top expert on right ventricular (RV) failure, to break down everything you need to know about this tricky condition. RV failure happens when the right side of the heart struggles to pump properly, messing with blood flow through the lungs and raising pressure in the veins. It shows up in a bunch of serious illnesses like pulmonary hypertension, left heart failure, and sepsis.

Dr. Tedford walks us through how to spot RV failure using key measurements from right heart catheterization, like right atrial pressure and the pulmonary artery pulsatility index (PAPi).

He also shares a simple, practical approach to managing RV failure: avoid overloading the heart with fluids, lower the pressure, the right heart has to pump against with pulmonary vasodilators, and boost its strength with inotropes like dobutamine. And when things get really serious, mechanical support might be needed. The good news? The right ventricle is pretty resilient, and with the right care, patients can bounce back.

Key Takeaways

• RV failure is a clinical syndrome due to dysfunction in any part of the right heart circulatory system, not just the RV itself.

• Don't skip hemodynamics: Right heart cath data is essential to distinguish RV from LV failure and guide therapy.

• Afterload reduction strategies include managing left-sided filling pressures and careful ventilator settings (avoid high PEEP and hyperinflation).

• [00:00] Introduction

• [01:39] Defining right ventricular failure

• [02:14] Importance of the right heart in critical care

• [03:57] Role of hemodynamic evaluation

• [04:12] Key hemodynamic metrics for RV failure

• [05:19] Echo vs. hemodynamics in RV failure

• [08:01] Treatment strategies: preload, afterload, and contractility

• [10:04] Avoiding hypotension and ischemia

• [11:16] Stepwise vs. immediate mechanical support

• [12:07] Prognosis and recovery of RV failure

• [02:02] "Although the RV is one of the biggest and perhaps most important components of the right heart circulatory system, actually any part of the right heart circulatory system can contribute to overall right heart failure." — Dr. Ryan Tedford

• [02:43] "If you go back, you know, 30 years or 80 years, in fact, the right heart has been largely ignored." — Dr. Ryan Tedford

• [04:04] "A comprehensive hemodynamic evaluation is really key. And I would say you really can't get it right without the right heart catheterization." — Dr. Ryan Tedford

Dr. Ryan Tedford

Dr. Tedford is a Professor of Medicine/Cardiology and holds the Dr. Peter C. Gazes Endowed Chair in Heart Failure at the Medical University of South Carolina (MUSC). He directs the Advanced Heart Failure and Transplant Fellowship and serves as the section head of heart failure and medical director of cardiac transplantation. An internationally recognized researcher with over 200 publications, his work focuses on right ventricular function, pulmonary hypertension, and hemodynamics.

Resources and Links

• Become a member of the Community: https://www.soccc.org/subscribe

Dr. Ryan Tedford

• https://www.linkedin.com/in/ryan-tedford-7163aa6/

Dr. Anthony Carnicelli

• https://www.soccc.org/

• https://www.linkedin.com/in/anthony-carnicelli-926a0b88/

Mentioned 

• Pragmatic approach to temporary mechanical circulatory support in acute right ventricular failure by Dr. Anthony Carnicelli

Supported By:

This episode is made possible by unrestricted support from Zoll LifeVest — thanks for keeping high-impact education free for our community.

Disclaimer

This podcast is not medical advice, just candid, practical discussions about what your hosts do every day in the CICU. Always consult your supervising team and current guidelines before applying any interventions.