The show busts out of studios and quiet intimate spaces for an on-stage performance at the Dakota Jazz Club in Minneapolis. Comedian Mike Brown joins us for plenty of comedy and conversation. We even bust out a few games where you can play along and see if you can tell a Pokemon from an antidepressant from a weird food served at the Minnesota State Fair.

Although she comes across as confident and happy on her incredibly successful YouTube channel, Hannah Hart has plenty of experience with insecurity and misery in her life. Growing up, she faced severe poverty, hunger, and dealing with a mother who was mentally ill. Still, she made it into a good college where she had to confront issues about her religion and her sexuality on her way to getting two degrees and not being able to be proud of any of it because of depression. Today, she's a star, dispensing advice on life, relationships, and how to cook when you're completely drunk. Life is full of unexpected paths sometimes. This is our final episode of season 2, but stay tuned for season 3 and bonus placebo episodes between seasons.

Although she comes across as confident and happy on her incredibly successful YouTube channel, Hannah Hart has plenty of experience with insecurity and misery in her life. Growing up, she faced severe poverty, hunger, and dealing with a mother who was mentally ill. Still, she made it into a good college where she had to confront issues about her religion and her sexuality on her way to getting two degrees and not being able to be proud of any of it because of depression. Today, she's a star, dispensing advice on life, relationships, and how to cook when you're completely drunk. Life is full of unexpected paths sometimes. This is our final episode of season 2, but stay tuned for season 3 and bonus placebo episodes between seasons.

It's hard to settle on a musical description for Ted Leo. We ended up going with "if The Beach Boys were '80s skateboarders" to summarize his melodic intense post-punk sound. Similarly hard to nail down is whether Ted's longtime issues with depression and anger stem from his brain's built-in wiring or from abuse he suffered as a kid and barely ever talked about since.

Rachel Bloom has never moved across the country to chase a boy like Rebecca Bunch did. Rebecca is the character Rachel plays in "Crazy Ex-Girlfriend," the hit show she co-created and stars in on The CW Network. But Rachel does have a long history of messed up romantic relationships -- plus depression and intrusive looping thoughts. And her career really took off when she got inspired by another Rebecca: Rebecca Black. You, know. That 2011 song "Friday?" Yep.

In one of the last interviews he gave, Reggie Osse, aka Combat Jack, talks about the connection between the status of the African-American man in contemporary society, the changing role of masculinity in hip-hop culture, and mental health. Osse was an important figure in hip-hop as a lawyer, editor, podcast host, and thinker. This interview was conducted in October of 2017, and Osse died on December 20th of that year.

Before she was the host of NPR's popular Pop Culture Happy Hour podcast, Linda Holmes was an attorney working at the Minnesota Legislature. Before that, she was a student living in squalor. And before that, she was the victim of some seriously messed up mean kid behavior. We hear about her unusual path to a better life, the older and very recent struggles she has had, and how the written word proved redemptive. We also hear about how Linda's weight was seen as a symptom of her depression when in fact the depression itself was the problem all along.

If you've ever heard this show before, you've heard singer-songwriter Rhett Miller. He wrote and performs the theme song about "the world's greatest clown." On this episode, Rhett tells of his teenage suicide attempt, a mysterious illness, his musical salvation, and his grandmother's owl fixation. He even brought his guitar along and performs a few songs.

New York comedian Mike Brown is a big fan of objective cause-and-effect scenarios. This drew him into playing video games, studying math and engineering, and ultimately getting on stage to tell jokes and get laughs. The thing is, sometimes you have to face events that are completely senseless.