Dr. Patrick Hwu sits down with Dr. Thomas Gajewski, a leader in tumor immunology at the University of Chicago. Dr. Gajewski discusses his pioneering work defining “hot” versus “cold” tumors — an insight that transformed how immunotherapists understand tumor response. The conversation dives into how the tumor microenvironment, patient genetics and even the gut microbiome shape immune activity in cancer. His work continues to drive strategies to turn cold tumors into responsive ones, giving new hope to patients across all cancer types. 

What You’ll Learn from Dr. Gajewsk

Access more show notes, links and transcript here: https://www.moffitt.org/about-moffitt/podcasts/immunoverse/hot-vs-cold-tumors/

Dr. Patrick Hwu welcomes Dr. Elizabeth Jaffee of Johns Hopkins, a renowned leader in cancer immunotherapy.

Dr. Jaffee shares the personal and scientific journey that led her to tackle one of oncology’s toughest challenges: pancreatic cancer. From her early fascination with virology to pioneering the use of genetically modified tumor vaccines, she has pushed the boundaries of what’s possible in cancer prevention and treatment.

What You’ll Learn from Dr. Jaffee

Dr. Jaffee also discusses efforts to use immunotherapy earlier — even preventively — and explores how AI and multi-modal data could revolutionize cancer risk prediction and early detection.

Key Takeaways

Access more show notes, links and transcript here: https://www.moffitt.org/about-moffitt/podcasts/immunoverse/targeting-kras/

Host Dr. Patrick Hwu sits down with immunotherapy pioneer Dr. James Mulé to discuss the origins and evolution of T cell therapies, groundbreaking discoveries at the NCI, and the translation of research to patient care at Moffitt Cancer Center.

Host Dr. Patrick Hwu sits down with trailblazing immunologist Dr. Phil Greenberg of Fred Hutchinson Cancer Center to explore how engineered T cells are revolutionizing cancer treatment. From early experiments in synthetic biology to today's clinical breakthroughs, Dr. Greenberg shares his decades-long journey to harness and rewire the immune system, turning obstacles into opportunities and transforming science fiction into standard of care.

In the premiere episode of The ImmunoVerse, host Dr. Patrick Hwu sits down with pioneering physician-scientist Dr. Steven A. Rosenberg, Chief of Surgery Branch at the National Cancer Institute. Together, they explore the roots of Dr. Rosenberg’s fascination with the immune system, tracing his remarkable journey from early scientific curiosity to the groundbreaking immunology discoveries that have reshaped cancer treatment.

Welcome to The ImmunoVerse™, a podcast exploring the past, present, and future of immunotherapy. In each episode, join Dr. Patrick Hwu as he sits with pioneering experts who are shaping the future of cancer treatment—uncovering breakthroughs, challenges, and the science driving this life-saving innovation. Don’t miss out—subscribe to The ImmunoVerse™ now and listen on your favorite podcast platforms!