In this episode, Prof Chapman answers a listener’s question about whether frozen embryos should be thawed, genetically tested, and refrozen for PGT. He explains the small risk of embryo loss associated with the process, how PGT can significantly improve the chances of selecting a genetically normal embryo, and why the decision often depends on age, embryo numbers, and individual fertility goals. Prof Chapman also discusses the differences between testing day-one and day-five embryos, the impact of maternal age on embryo genetics, and how PGT can reduce the emotional, financial, and physical burden of multiple unsuccessful embryo transfers. This practical discussion offers valuable guidance for anyone considering genetic testing as part of their IVF journey.