Bruce Trapp and Daniel Ontaneda discuss their retrospective study investigating cortical neuronal loss and cerebral white-matter demyelination in mulitple sclerosis.

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Josep Dalmau joins The Lancet Neurology to discuss recognition and outcomes of autoimmune encephalitis after herpes simplex encephalitis.

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David Eidelberg and Katharina Schindelbeck join The Lancet Neurology to explain their new review of the applications of network imaging biomarkers in Parkinson's disease.

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Eugene Major and David Clifford join The Lancet Neurology to discuss their review of pathogenesis and treatments for progressive multifocal leukoencephalopathy.

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Torbjörn Tomson discusses the issue of antiepileptic drugs during pregnancy and the risk of major congenital malformations.

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Christian Elger discusses the diagnostic challenges in epilepsy with the detection and reporting of seizures.

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Jeffrey Cohen joins us to talk about the process of updating and revising the McDonald criteria for diagnosis of MS.

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Jose Bras discusses his study of the genetic architecture of dementia with Lewy bodies.

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Andrew Maas and David Menon, lead authors, discuss The Lancet Neurology Commission on traumatic brain injury and outline the worldwide burden.

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Keith Josephs talks about considering TDP-43 as a potential factor related to increased rates of hippocampal atrophy in patients with Alzheimer's disease.

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