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The Lead Podcast - Episode 103: A Discussion of Independent External Evaluation of Pediatric Hypertrophic Cardiomyopathy Risk Scores... Live at HRS 2025 in San Diego
Join host Elizabeth S DeWitt, MD, CEPS-P, and episode guests Cheyenne Beach, MD, FHRS, CEPS-P, and Robert Przybylski, MD as they discuss Sudden cardiac death is the leading cause of mortality in children with hypertrophic cardiomyopathy (HCM). Two risk scores—HCM Risk-Kids and PRIMaCY—have been developed to estimate 5-year risk, but their performance in an independent cohort showed limitations. Both tools tended to overestimate risk and showed imperfect ability to distinguish between low- and high-risk patients. However, their predictive accuracy significantly improved when risk assessments were repeated over time during follow-up.
https://www.hrsonline.org/education/TheLead https://www.ahajournals.org/doi/abs/10.1161/CIRCEP.124.012932
Host Disclosure(s):
E. DeWitt: Nothing to disclose.
Contributor Disclosure(s):
C. Beach: Nothing to disclose.
R. Przybylski: Nothing to disclose.
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By The Lead Podcast presented by Heart Rhythm Society
5
77 ratings
Join host Elizabeth S DeWitt, MD, CEPS-P, and episode guests Cheyenne Beach, MD, FHRS, CEPS-P, and Robert Przybylski, MD as they discuss Sudden cardiac death is the leading cause of mortality in children with hypertrophic cardiomyopathy (HCM). Two risk scores—HCM Risk-Kids and PRIMaCY—have been developed to estimate 5-year risk, but their performance in an independent cohort showed limitations. Both tools tended to overestimate risk and showed imperfect ability to distinguish between low- and high-risk patients. However, their predictive accuracy significantly improved when risk assessments were repeated over time during follow-up.
https://www.hrsonline.org/education/TheLead https://www.ahajournals.org/doi/abs/10.1161/CIRCEP.124.012932
Host Disclosure(s):
E. DeWitt: Nothing to disclose.
Contributor Disclosure(s):
C. Beach: Nothing to disclose.
R. Przybylski: Nothing to disclose.
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