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Deepthy Varghese, MSN, FNP of Northside Hospital is joined by guests, Niraj Sharma, MD, FHRS, of Northside Hospital, and Kamala P. Tamirisa, of Texas Cardiac Arrhythmia to discuss early versus later anticoagulation for stroke with atrial fibrillation. In this trial, the incidence of recurrent ischemic stroke, systemic embolism, major extracranial bleeding, symptomatic intracranial hemorrhage, or vascular death at 30 days was estimated to range from 2.8 percentage points lower to 0.5 percentage points higher (based on the 95% confidence interval) with early than with later use of DOACs. (Funded by the Swiss National Science Foundation and others; ELAN ClinicalTrials.gov number, NCT03148457.)
https://www.hrsonline.org/education/TheLead
Host Disclosure(s):
D. Varghese: No relevant financial relationships with ineligible companies to disclose.
Contributor Disclosure(s):
N. Sharma: No relevant financial relationships with ineligible companies to disclose.
K. Tamirisa: Honoraria/Speaking/Consulting Fee: Medscape, Abbott, Sanofi
By The Lead Podcast presented by Heart Rhythm Society5
77 ratings
Deepthy Varghese, MSN, FNP of Northside Hospital is joined by guests, Niraj Sharma, MD, FHRS, of Northside Hospital, and Kamala P. Tamirisa, of Texas Cardiac Arrhythmia to discuss early versus later anticoagulation for stroke with atrial fibrillation. In this trial, the incidence of recurrent ischemic stroke, systemic embolism, major extracranial bleeding, symptomatic intracranial hemorrhage, or vascular death at 30 days was estimated to range from 2.8 percentage points lower to 0.5 percentage points higher (based on the 95% confidence interval) with early than with later use of DOACs. (Funded by the Swiss National Science Foundation and others; ELAN ClinicalTrials.gov number, NCT03148457.)
https://www.hrsonline.org/education/TheLead
Host Disclosure(s):
D. Varghese: No relevant financial relationships with ineligible companies to disclose.
Contributor Disclosure(s):
N. Sharma: No relevant financial relationships with ineligible companies to disclose.
K. Tamirisa: Honoraria/Speaking/Consulting Fee: Medscape, Abbott, Sanofi

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