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Welcome back Rounds Table Listeners! We are back today with a solo episode with Dr. John Fralick. This week, he discusses a recently published trial examining liberal fluid intake vs. fluid restriction in chronic heart failure. Here we go!

1. Liberal fluid intake versus fluid restriction in chronic heart failure: a randomized clinical trial (0:00 – 4:20).

And for the Good Stuff:

• starpowerdrummer on YouTube (4:21 – 5:20).

Questions? Comments? Feedback? We’d love to hear from you! @roundstable @InternAtWork @MedicinePods

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Welcome back Rounds Table Listeners! We are back today with a solo episode with Dr. Mike Fralick. This week, he discusses a recently published trial exploring the role of high-dose Vitamin D therapy in reducing disease activity in patients with clinically isolated syndrome (CIS) typical of multiple sclerosis (MS). Here we go!

1. High-Dose Vitamin D in Clinically Isolated Syndrome Typical of Multiple Sclerosis: The D-Lay MS Trial (0:00 – 7:35).

Announcements (7:36 – 9:15):

• Canadian physicians, 2025 CMPA Council elections are underway in Alberta and Ontario! View the candidates and cast your ballot here.
• Check out Dr. Yatin Chada's podcast, beyondMD!

And we've launched qMonthly, a monthly blog highlighting headliners and hidden gem trials published each month. Check it out here!

Questions? Comments? Feedback? We’d love to hear from you! @roundstable @InternAtWork @MedicinePods

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Welcome back Rounds Table Listeners! We are back today with a special Rapid Fire Podcast! This week, Drs. Mike and John Fralick discuss top papers from the 2025  American College of Cardiology (ACC) Annual Scientific Session. Hot off the presses, here we go!

1. Extended Reduced-Dose Apixaban for Cancer-Associated Venous Thromboembolism (0:00 - 5:55)
2. Dapagliflozin in Patients Undergoing Transcatheter Aortic-Valve Implantation (DapaTAVI) (5:56 - 9:51)
3. Oral Semaglutide and Cardiovascular Outcomes in High-Risk Type 2 Diabetes (9:52 - 14:04)
4. Semaglutide and walking capacity in people with symptomatic peripheral artery disease and type 2 diabetes (STRIDE) (14:05 - 18:36)

The Good Stuff:

• The Studio TV series on Apple (18:37 - 19:11)
• Cardiology Trial Files (19:12 - 20:40)

Questions? Comments? Feedback? We’d love to hear from you! @roundstable @InternAtWork @MedicinePods

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Welcome back Rounds Table Listeners! We are back today with our Classic Rapid Fire Podcast! This week, Dr. John Fralick and guest host Dr. Chunpeng Nie discuss two recent papers: resmetirom for the treatment of Nonalcoholic Steatohepatitis (NASH)—now known as Metabolic Dysfunction-Associated Steatohepatitis (MASH)—with liver fibrosis, and the effect of a Mediterranean diet on disease activity, inflammation, and the gut microbiome in patients with ulcerative colitis. Two papers, here we go!

1. A Phase 3, Randomized, Controlled Trial of Resmetirom in NASH with Liver Fibrosis (0:00 – 10:17)
2. A Mediterranean Diet Pattern Improves Intestinal Inflammation Concomitant with Reshaping of the Bacteriome in Ulcerative Colitis: A Randomised Controlled Trial (10:18– 15:45)

And for the Good Stuff:

• Shoutout to all the MTU teams supporting their R1's! (15:46 – 16:20).
• For the 1st time in Canada, surgeons put teeth in patients' eyes to restore sight (16:21 – 17:56)

Questions? Comments? Feedback? We’d love to hear from you! @roundstable @InternAtWork @MedicinePods

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Welcome back Rounds Table Listeners! In this throwback episode, Drs. Mike and John Fralick chat about five important research studies published in 2023:

1. Hydrocortisone in Severe Community-Acquired Pneumonia (0:00 – 5:39).
2. Tirzepatide vs Insulin Lispro Added to Basal Insulin in Type 2 Diabetes (5:40 – 8:48).
3. Semaglutide and Cardiovascular Outcomes in Obesity without Diabetes (8:49 – 12:29).
4. Cefepime vs Piperacillin-Tazobactam in Adults Hospitalized With Acute Infection (12:30 – 17:49).
5. Early versus Later Anticoagulation for Stroke with Atrial Fibrillation (17:50 – 23:38).

And for the Good Stuff:

• The Beckham docuseries on Netflix (23:39 – 24:15)
• Upside Drinks (24:16 – 26:04).

Questions? Comments? Feedback? We’d love to hear from you! @roundstable @InternAtWork @MedicinePods

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Welcome back Rounds Table Listeners!

We are back this week with a special podcast episode! Dr. Mike Fralick sits down with Dr. Jeffrey Carson, Distinguished Professor of Medicine at the Rutgers Robert Wood Johnson Medical School and Provost at Rutgers University, to chat about his recent publication - Restrictive versus Liberal Transfusion in Myocardial Infarction — A Patient-Level Meta-Analysis. Here we go!

Questions? Comments? Feedback? We’d love to hear from you! @roundstable @InternAtWork @MedicinePods

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Welcome back Rounds Table Listeners! We are back today with our Classic Rapid Fire Podcast! This week, Drs. Mike and John Fralick discuss two recent papers examining the effect of glucagon-like peptide-1 receptor agonists (GLP1's) on patients living with Parkinson’s disease. Two papers, here we go!

1. Trial of Lixisenatide in Early Parkinson's Disease (0:00 – 10:24).
2. Exenatide once a week versus placebo as a potential disease-modifying treatment for people with Parkinson's disease (10:25 – 17:40).

And for the Good Stuff:

• Port Blandford artist creates portraits from Scotch tape (17:41 – 18:33).
• Rheumatology for the Royal College podcast (18:34 – 19:42).

This episode is sponsored by Northern Ontario Resident Streamlined Training and Reimbursement Program (NORSTAR). Check out details here!

Questions? Comments? Feedback? We’d love to hear from you! @roundstable @InternAtWork @MedicinePods

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Welcome back Rounds Table Listeners! We are back today with a solo episode with Dr. Mike Fralick. This week, he will discuss a paper exploring endovascular treatment (EVT) for acute ischemic stroke due to medium-vessel occlusion. Here we go!

• Endovascular Treatment of Stroke Due to Medium-Vessel Occlusion (0:00 – 6:02).

This episode is sponsored by Northern Ontario Resident Streamlined Training and Reimbursement Program (NORSTAR). Check out details here!

Questions? Comments? Feedback? We’d love to hear from you! @roundstable @InternAtWork @MedicinePods

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Welcome back Rounds Table Listeners!

We are back today with our Classic Rapid Fire Podcast!

This week, Drs. Mike and John Fralick discuss two recent papers - the role of continuous glucose monitoring for diabetes management in hospital and the benefit of tirzepatide in patients with heart failure with preserved ejection fraction and obesity. Two papers, here we go!

1. Tirzepatide for Heart Failure with Preserved Ejection Fraction and Obesity (0:00 – 11:26).
2. DIATEC: A Randomized Controlled Trial (11:26 – 19:56).

And for the Good Stuff:

• Surgeons successfully transplant genetically edited pig kidney into U.S. man (19:56 – 20:55).
• Diabetes Trial Files (20:55 – 22:25)

Questions? Comments? Feedback? We’d love to hear from you! @roundstable @InternAtWork @MedicinePods

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Welcome back Rounds Table Listeners!

We are back this week with a special podcast episode! Dr. Mike Fralick sits down with Dr. Amy Yu, a Stroke Neurologist, Clinician-Scientist, and Associate Professor of Medicine at the University of Toronto and Sunnybrook Hospital, to chat about her hot-off-the press publication - Population-Level Screening for Diabetes and Dyslipidemia After Pregnancies Complicated by Hypertension or Diabetes!

Questions? Comments? Feedback? We’d love to hear from you! @roundstable @InternAtWork @MedicinePods