The Rounds Table

This week: Statins for COPD, ARDS and human-bovine Rotavirus vaccine Fahad and Amol want you to: 1. Understand that 2 high quality RCTs demonstrate that statins are not effective in improving clinical outcomes in either COPD or Acute Respiratory Distress Syndrome (ARDS). 2. Recognize that a novel Rotavirus vaccine was developed through an international public-private partnership that is ...

The post Sorry Sports Analogies: Statins in ARDS and COPD, Rotavirus Vaccine appeared first on Healthy Debate.

This week: Cryptogenic Stroke and Atrial Fibrillation, Naloxegol for Opioid-Induced Constipation Fahad and Amol want you to: 1. Appreciate the importance of subclinical atrial fibrillation in cryptogenic stroke and consider longer monitoring to detect it. 2. Recognize Naloxegol as a targeted therapy for opioid-induced constipation that is more effective than placebo but its effectiveness has not been compared directly with existing laxative therapies. ...

The post Getting “Travis-y”: Stroke and AFib, Naloxegol for Opioid Constipation appeared first on Healthy Debate.

This week: Vitamin D Levels and All-Cause Mortality, Vitamin C and Infant Lung Outcomes in Pregnant Smokers Reena and Amol want you to: 1. Recognize the potential association between Vitamin D levels and overall mortality. 2. Recognize that Vitamin C supplementation in pregnant women who smoke can improve infant lung outcomes (though it has not been shown to improve ...

The post Vitamania: Vitamin D and Mortality, Vitamin C and Smoking in Pregnancy appeared first on Healthy Debate.

This week: Bionic Pancreas in Type 1 Diabetes and Weekly Dalbavancin for Skin Infections Travis and Amol want you to: 1. Understand the potential role of a novel bionic pancreas in glycemic control in type 1 diabetes. 2. Recognize that dalbavancin is non-inferior to vancomycin/linezolid in treating skin infections and represents a potentially revolutionary once weekly approach to ...

The post Super Cool Stuff: A Bionic Pancreas and Weekly Antibiotics appeared first on Healthy Debate.

This week: Perioperative Aspirin and Blood Transfusions and Hospital-acquired Infections Nathan and Amol want you to: 1. Understand that the use of perioperative ASA did not reduce the rate of postoperative MI or death, but was found to increase the rate of major bleeding. 2. Recognize that it may be difficult to generalize the findings of the POISE-2 ...

The post Yin and Yang 2.0: Revisiting Aspirin and Blood Transfusions appeared first on Healthy Debate.

This week: Protocol-based care for septic shock and a new treatment for allergen-induced asthma Janice and Amol want you to: 1. Recognize the role of protocol-based care in the early recognition and management of septic shock. 2. Recognize that TSLP is a promising new treatment target in allergy-induced asthma. Continuing Medical Education Internists can receive 0.5 hours of Continuing ...

The post Filling Buckets: Septic Shock and Asthma appeared first on Healthy Debate.

This week: A Randomized Trial of Bariatric Surgery vs. Medical Management; Physical Activity and the Risk of Type II Diabetes in patients with Gestational Diabetes Nathan and Amol want you to: 1. Recognize that bariatric surgery led to superior diabetes control compared to intensive medical management in a single centre randomized controlled trial over a 3 year follow up ...

The post All About Diabetes: Bariatric Surgery and Physical Activity appeared first on Healthy Debate.

This week: Nurse Staffing and Education and Hospital Mortality; Appropriate Use of Coronary Angiography   Nathan and Amol want you to: 1. Understand that this study demonstrated relationships between nurse to patient ratio and average nurse education level to post-operative mortality among a large cohort of European patients. 2. Recognize different approaches to studying appropriateness and that variability in ...

The post Great Minds Think Alike: Nurse Staffing and Appropriateness of Coronary Angiography appeared first on Healthy Debate.

This week: Perioperative Aspirin and Blood Transfusions and Hospital-acquired Infections Nathan and Amol want you to: 1. Understand that the use of perioperative ASA did not reduce the rate of postoperative MI or death, but was found to increase the rate of major bleeding. 2. Recognize that it may be difficult to generalize the findings of the POISE-2 ...

The post Yin and Yang: Aspirin and Surgical Risk and Blood Transfusions and Risk of Infection appeared first on Healthy Debate.

This week: Cardiovascular Disease and Population Health Fahad and Amol want you to: 1. Understand that high quality evidence now demonstrates that obesity does not confer a survival benefit in Type 2 Diabetes, and patients should aim to achieve a normal body weight. 2. Recognize that the new cholesterol guidelines move away from specific lipid targets and recommend statin therapy ...

The post Dropping Names and Dropping Weight: The obesity paradox and new cholesterol guidelines appeared first on Healthy Debate.