After pledging the House will vote on both the bipartisan infrastructure and the Democrats’ reconciliation packages, George goes one-on-one with Speaker Pelosi on the fate of Pres. Biden’s signature legislation. ABC Exclusive: After the CDC endorsed booster shots of the Pfizer vaccine for older and high-risk Americans, Pfizer Chairman and CEO Albert Bourla joins George to discuss the rollout plan plus vaccine authorization for children under 11. ABC Exclusive: In his first television interview, whistleblower and former top Trump DHS official Brian Murphy talks to George about DHS downplaying the threat of Russian election interference and white supremacist groups. Plus, the Powerhouse Round Table.

With an FDA advisory panel recommending Pfizer booster shots only for those over 65 or at high risk, Martha goes one-on-one with Dr. Anthony Fauci on the latest setback for the Biden administration in its booster plan push. After the Pentagon admitted a drone strike that killed 10 Afghan civilians was a mistake, Martha interviews Adm. Mike Mullen on the tragedy and Joint Chiefs Chairman Milley’s calls to China in the final months of the Trump presidency. Following a powerful day of testimony from U.S. gymnasts on the sexual abuse they suffered by team doctor Larry Nassar, Pierre Thomas and Christine Brennan join Martha to discuss the FBI’s failure in handling the case and what comes next.

After Pres. Biden announced a sweeping new vaccine mandate amid the delta variant, Surgeon General Vivek Murthy joins George to discuss how the administration plans to enforce the policy and the potential legal challenges from GOP governors. After calling for a pause in the Democrats' $3.5T economic package, George interviews Sen. Joe Manchin and goes one-on-one with Sen. Bernie Sanders on his strategy for passing the bill amid pushback from moderate Democrats. Plus the Powerhouse Roundtable.

Hurricane Ida devastated Louisiana and the northeast, causing flooding and killing dozens of people. ABC "This Week" anchor George Stephanopoulos goes one-one-one with White House Senior Advisor Cedric Richmond about what types of federal emergency assistance President Biden is prepared to authorize. The Supreme Court voted not to block a Texas law that would make it illegal to have an abortion after six weeks. Republican Senator Bill Cassidy spoke with George about the decision from the Supreme Court, and relief efforts in Louisiana. The nation will mark 20 years since 9/11 as the country absorbs more harrowing scenes from the chaotic exit out of Afghanistan, and George speaks with ABC's Martha Raddatz, Pierre Thomas, and retired ABC News broadcaster Charlie Gibson about that fateful day.

Collapse into chaos. The Biden administration is in damage control as the Taliban seizes power in Afghanistan, the military racing to evacuate Americans and our Afghan allies left behind. ABC "This Week" co-anchor Martha Raddatz sits down exclusively with US Defense Secretary Lloyd Austin, asking is the Pentagon was prepared -- and could the mission expand? Also, US Surgeon General Vivek Murthy has what you need to know about COVID-19 booster shots.

Following the deadly terror attack that killed 13 U.S. service members and an estimated 170 Afghans, Martha Raddatz interviews Secretary Blinken about the race to evacuate Americans and allies from Afghanistan before the August 31 deadline. Martha goes one-on-one with Senator Sasse about his call for the U.S. to maintain a “light footprint” in Afghanistan. With COVID hospitalizations passing 100,000 for the first time since January, Martha Raddatz goes one-on-one with Dr. Fauci. Plus, the power house roundtable.

With the Taliban gaining control of Afghanistan as the U.S. prepares for final withdrawal, Chief Washington Correspondent Jonathan Karl goes one-on-one with Secretary Antony Blinken and Wyoming Representative Liz Cheney. Karl speaks with Dr. Richard Besser on COVID-19. Plus, the Powerhouse Round table

COVID-19 hospitalizations are up over 40%, overwhelming health care workers in the hardest hit states as the Delta variant sweeps through the U.S. National Institutes of Health Director Dr. Francis Collins joined George to discuss the Delta variant, mask mandates, and vaccination rates picking as more than 50% of Americans are now fully vaccinated; American troops have begun returning home from Afghanistan, but questions remain if Afghans who aided the U.S. in it's longest war, can be saved with the Taliban sweeping through the country. George interviewed Ryan Crocker, U.S. Ambassador to Afghanistan during the war, and Janis Shinwari, a former Afghan interpreter for the U.S. military, to find out more; Record heatwaves and severe droughts rage on the west coast and abroad in Greece, Turkey, and Russia. Professor Michael Mann and Climate Scientist Kristina Dahl joined George to discuss what's causing these wildfires, and what can be done; Plus the Power House Roundtable discuss the latest on the infrastructure deal and the New York attorney general's report into allegations of sexual harassment by Governor Andrew Cuomo.

As Covid cases and hospitalizations reach their highest levels in months amid the surging delta variant, Chief Washington Correspondent Jonathan Karl goes one-on-one with Dr. Anthony Fauci about the divide over vaccine and mask mandates. Karl interviews Transportation Secretary Pete Buttigieg and Republican Representative Adam Kinzinger. Devin Dwyer speaks with Joel Caston, a convicted felon and the newest elected public servant in Washington, D.C., after he won a groundbreaking local election while incarcerated. Plus, the Powerhouse Round table

After rejecting two House GOP members with strong ties to former Pres. Trump from the Jan 6 commission, Speaker of the House Nancy Pelosi joins George s to discuss the future of the investigation, plus the latest on infrastructure; As Senate negotiators race to finalize a bipartisan infrastructure plan ahead of Monday’s possible vote, George interviews lead GOP negotiator Ohio Senator Rob Portman about the remaining sticking points in talks; ABC News Chief Justice Correspondent Pierre Thomas chronicles one week of gun violence in America for “One Nation Under Fire,” giving a humanizing look at this relentless trend, exploring the root causes of violence, and telling the stories of the victims and families; Plus the Power House Roundtable.