Jon Cohen, senior correspondent with Science, reports on how countries that suffer high rates of HIV/AIDS are coping now that USAID funding has dried up, and how local governments, especially in places like Lesotho, are attempting to figure out solutions. Plus, Wafaa El-Sadr, MD, Columbia University professor of epidemiology and medicine and director of ICAP, a global health center at the school of public health, discusses ICAP's work in implementing PEPFAR (the President’s Emergency Plan for AIDs Relief) in sub-Saharan Africa, and discusses the future of PEPFAR under the Trump administration.