This Week in Virology

TWiV 829: Antiviral and cytotoxically empowered for COVID-19


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A TWiV duo reviews how SARS-CoV-2 attacks the olfactory mucosa but spares the olfactory bulb, vaccination with BNT162b2 induces virus-specific stem cell memory T cells, and development of an oral protease inhibitor for the treatment of COVID-19.

Hosts: Vincent Racaniello and Brianne Barker

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Links for this episode
  • How SARS-CoV-2 attacks olfactory mucosa (Cell)
  • SARS-CoV-2-specific stem cell memory T cells after mRNA vaccine (Sci Immunol)
  • Oral SARS-CoV-2 protease inhibitor (Science)
  • Paxlovid phase 2/3 trial preliminary results (Pfizer)
  • Letters read on TWiV 829
  • Timestamps by Jolene. Thanks!
Weekly Picks

Brianne – Coronavirus Neutralizing Antibodies and mRNA Vaccine Video Vincent – MHC restriction of cytotoxic T cell lysis (Nobel description)

Listener Picks

Lisa – Shall Furnish Medicine Bistra – Saving the World by Julia Alvarez

Intro music is by Ronald Jenkees Send your virology questions and comments to [email protected]

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This Week in VirologyBy Vincent Racaniello

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