
Sign up to save your podcasts
Or
We’re back with another Rapid Fire Journal Club. Luke Hedrick and Dave Furfaro discuss the NAVIGATOR trial published in NEJM in 2021 evaluating tezepelumab for adults with asthma.
Article and Reference
We are talking today about the NAVIGATOR trial evaluating the use of tezepelumab in adults with asthma.
Menzies-Gow A, Corren J, Bourdin A, Chupp G, Israel E, Wechsler ME, Brightling CE, Griffiths JM, Hellqvist Å, Bowen K, Kaur P, Almqvist G, Ponnarambil S, Colice G. Tezepelumab in Adults and Adolescents with Severe, Uncontrolled Asthma. N Engl J Med. 2021 May 13;384(19):1800-1809. doi: 10.1056/NEJMoa2034975. PMID: 33979488.
https://www.nejm.org/doi/full/10.1056/NEJMoa2034975
Key Learning Points
Background & Rationale
Study Design (Navigator Trial)
Outcomes
Key Inclusion/Exclusion
Patient Population (Table 1 Summary)
Results
Efficacy:
Safety:
Overall Takeaway
Infographic:
4.9
5252 ratings
We’re back with another Rapid Fire Journal Club. Luke Hedrick and Dave Furfaro discuss the NAVIGATOR trial published in NEJM in 2021 evaluating tezepelumab for adults with asthma.
Article and Reference
We are talking today about the NAVIGATOR trial evaluating the use of tezepelumab in adults with asthma.
Menzies-Gow A, Corren J, Bourdin A, Chupp G, Israel E, Wechsler ME, Brightling CE, Griffiths JM, Hellqvist Å, Bowen K, Kaur P, Almqvist G, Ponnarambil S, Colice G. Tezepelumab in Adults and Adolescents with Severe, Uncontrolled Asthma. N Engl J Med. 2021 May 13;384(19):1800-1809. doi: 10.1056/NEJMoa2034975. PMID: 33979488.
https://www.nejm.org/doi/full/10.1056/NEJMoa2034975
Key Learning Points
Background & Rationale
Study Design (Navigator Trial)
Outcomes
Key Inclusion/Exclusion
Patient Population (Table 1 Summary)
Results
Efficacy:
Safety:
Overall Takeaway
Infographic:
1,871 Listeners
534 Listeners
248 Listeners
489 Listeners
3,318 Listeners
1,108 Listeners
191 Listeners
713 Listeners
512 Listeners
349 Listeners
248 Listeners
426 Listeners
250 Listeners
366 Listeners
238 Listeners