After looking at early upper gastrointestinal cancers last week, Michael and Josh take the logical next step and discuss the management of their metastatic cousins, the most unsavoury collection since Cassius and Brutus teamed up to assassinate their erstwhile friend Julius. And while our weapons against these cancers are limited, that will not stop our intrepid podcasting pair from taking a deep, rambling and irreverent dive into the dirty details. Friends! Oncologists! Countrymen! Lend us your ears!

Links to studies discussed in this episode (subscription may be required):

TOGA: https://www.thelancet.com/article/S0140-6736(10)61121-X/fulltext

CHECKMATE 649: https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(21)00797-2/fulltext

CHECKMATE 648: https://www.nejm.org/doi/full/10.1056/NEJMoa2111380

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