Oncology for the Inquisitive Mind returns to its regular broadcasting schedule and discusses metastatic renal cell cancer (ccRCC). As not to be outdone, Josh takes a cultural tangent exploring the world of opera after seeing "The Hours" broadcast through Met: Live in HD. While Josh doesn't sing this episode, he highlights this opera's parallels with cancer patients undergoing treatment. To avoid losing sight of this podcast's purpose, Michael and Josh soon find their way. They discovered that metastatic renal cell carcinoma has many treatment options, including targeted therapy, immunotherapy, or even combining these two modalities! Tune in to find out where the evidence currently stands.

Links to studies discussed in this episode (subscription may be required):

CHECKMATE 214: https://www.nejm.org/doi/full/10.1056/nejmoa1712126

KEYNOTE-426: https://www.nejm.org/doi/full/10.1056/NEJMoa1816714 

Other studies of interest:

CLEAR: https://www.nejm.org/doi/full/10.1056/NEJMoa2035716

CheckMate 9ER: https://www.nejm.org/doi/full/10.1056/nejmoa2026982

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Art courtesy of Taryn Silver

Music courtesy of AlexiAction: https://pixabay.com/users/alexiaction-26977400/

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