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SSRIs, antidepressants, and psilocybin–can you combine them? Many people are seeking an intentional psilocybin experience in order to combat depression, but very few know whether they can stay on their pharmaceutical medication or not. Some of these medications are medically contraindicated and some are not.
Hosts Nicholas and Jimmy Nguyen address the various types of medications (not just antidepressants) and how they can impact the psychedelic experience. They provide some general guidelines as well as actionable advice for anyone who is currently taking prescription medication and considering a psychedelic journey.
In this episode, the hosts discuss both the scientific studies and anecdotal evidence they’ve seen firsthand when it comes to combining antidepressants and psilocybin. They also highlight some of the profound shifts they’ve seen in their clients as well as how microdosing can help alleviate the withdrawal symptoms associated with tapering.
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About Us:
Psychedelic Passage is the nation’s first psychedelic concierge service. Our platform connects clients with a pre-vetted network of trusted, local facilitators across the country. We serve as an independent body that moderates the network of facilitators who all have their own private practice, which means we can advocate for you without a conflict of interest.
Our comprehensive vetting process ensures each hand-selected facilitator serves journeyers with integrity. The goal is to inspire trust, confidence, and lasting change for each journeyer. To date, our network of guides has facilitated hundreds of safe and transformational journeys for people all across the United States.
Visit our website or book a consultation to speak with a highly knowledgeable psychedelic concierge. They will get to know you and your situation and you’ll have all your questions answered.
More Psychedelic Passage:
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By Psychedelic Passage4.9
123123 ratings
SSRIs, antidepressants, and psilocybin–can you combine them? Many people are seeking an intentional psilocybin experience in order to combat depression, but very few know whether they can stay on their pharmaceutical medication or not. Some of these medications are medically contraindicated and some are not.
Hosts Nicholas and Jimmy Nguyen address the various types of medications (not just antidepressants) and how they can impact the psychedelic experience. They provide some general guidelines as well as actionable advice for anyone who is currently taking prescription medication and considering a psychedelic journey.
In this episode, the hosts discuss both the scientific studies and anecdotal evidence they’ve seen firsthand when it comes to combining antidepressants and psilocybin. They also highlight some of the profound shifts they’ve seen in their clients as well as how microdosing can help alleviate the withdrawal symptoms associated with tapering.
Additional Resources:
About Us:
Psychedelic Passage is the nation’s first psychedelic concierge service. Our platform connects clients with a pre-vetted network of trusted, local facilitators across the country. We serve as an independent body that moderates the network of facilitators who all have their own private practice, which means we can advocate for you without a conflict of interest.
Our comprehensive vetting process ensures each hand-selected facilitator serves journeyers with integrity. The goal is to inspire trust, confidence, and lasting change for each journeyer. To date, our network of guides has facilitated hundreds of safe and transformational journeys for people all across the United States.
Visit our website or book a consultation to speak with a highly knowledgeable psychedelic concierge. They will get to know you and your situation and you’ll have all your questions answered.
More Psychedelic Passage:
Feedback & Topic Suggestions Box
Like, share, and follow to stay connected with our growing community of psychedelic-curious folks!

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