Hey Functional Friends!

This week I’m speaking with one of my favorite humans and longtime mentors, the brilliant Kiran Krishnan — research microbiologist, educator, and co-founder of Microbiome Labs. We explore the evolution of functional medicine, the rise of evidence-based holistic practice, and how AI and new technologies are reshaping research. Kiran breaks down the future of microbiome testing, the truth about stool analysis, and why understanding terrain and sequencing interventions is key to better clinical outcomes. We also dive into his new Practitioner Microbiome Mastery Course, the importance of systems-based thinking, and how practitioners can elevate their results through data-driven, root-cause healing. As always, this was an inspiring, mind-expanding conversation — you’re going to love it.

00:00 – Intro + setting the stage for today’s episode

02:25 – Welcoming Kiran Krishnan back to the show

03:50 – Innovation, AI, and the future of clinical trials

06:00 – Elevating the holistic and functional medicine space with real evidence

09:00 – The need for practitioner education and Kiran’s new Microbiome Mastery course

12:30 – Why clinicians struggle with complexity and root-cause sequencing

17:00 – Stool testing: diagnostic limits, pros/cons, and what it really tells us

23:20 – Whole-genome vs PCR testing and the terrain-based model

31:10 – The “Whack-a-Mole” trap of chasing pathogens

39:00 – Why terrain and missing functions matter more than pathogens

46:00 – Understanding phyla ratios and ecosystem-level patterns

50:00 – How Kiran’s course teaches systems biology and clinical sequencing

56:00 – Foundational interventions and order of operations in healing

57:00 – The real deal on Urolithin A and microbiome-derived compounds

1:00:00 – Functional applications, muscle building, nitric oxide + future projects

Join the Waitlist for Kiran's Microbiome Clinical Science Certificate Program: https://learn.rebelhealth.co/mcsc-waitlist

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