In this episode, Josh and Michael once again tackle immunotherapy in its application to metastatic urothelial cancer. Some say immunotherapy should be used up front. Others say that it should be used when all previous treatments have failed. And still, others are wondering about that Richard Nixon/Spock impression from last week and how it could be topped. For answers to all those questions and more, you'll have to listen on...

Links to papers discussed in this episode (subscription may be required):

JAVELIN-100: https://www.nejm.org/doi/full/10.1056/NEJMoa2002788

KEYNOTE 045: https://www.nejm.org/doi/full/10.1056/nejmoa1613683

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Art courtesy of Taryn Silver

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