Alzheimers disease is now the leading cause of death in the UK, but there are as yet no treatments to halt or reverse it. There was huge disappointment last week when the drug company Eli Lilly announced that a large, phase 3 clinical trial had failed to show any benefit to mild dementia sufferers from its antibody therapy, solanezumab. So where does this leave our basic understanding of biology of Alzheimers disease and how we might most effectively treat or cure it? Adam Rutherford talks to Alzheimers researcher Tara Spires-Jones of the University of Edinburgh.

Also in the programme: The skeleton of the world's most famous fossil, Lucy, has received a body scan which revealed she spent a considerable portion of her life climbing trees. Researchers at the University of Bath are making smart bandages for burns patients which glow when their wounds become infected. Adam also talks to the astrophysicist who gave up studying exploding stars to apply his maths to Hollywood stars in the movie business.