“We play many musical instruments in our family. Lots of them produce the same pitch of notes, but the instruments all sound different. Why is this?” asks Natasha Cook aged 11, and her Dad Jeremy from Guelph in Ontario, Canada.

For this instrumental case Hannah and Adam are joined by the Curious Cases band - Matt Chandler and Wayne Urquhart - to play with today's question.

Bringing the science we have acoustic engineer and saxophone player Trevor Cox. Plus materials expert Zoe Laughlin demonstrates a selection of her unusual musical creations, including a lead bugle.

Presenters: Adam Rutherford, Hannah Fry

First broadcast on BBC Radio 4 in 2019.