Mixing lidocaine, ropivacaine, and bicarbonate is routine in many hospitals, but is it actually safe? In this episode, we discuss the main findings from a 2026 article by Gasteiger et al. (Anesthesiology), which questions the stability, efficacy, and safety of common local anesthetic mixtures. From crystal formation to reduced block performance, we explore why combining drugs may do more harm than good, and how to rethink this everyday practice.

Read more about this on NYSORA.com.

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Where else to find us: Web- ⁠⁠⁠⁠⁠⁠⁠http://www.nysora.com⁠⁠⁠⁠⁠⁠⁠ 

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⁠⁠⁠⁠⁠#nysora⁠⁠⁠⁠⁠⁠⁠ ⁠⁠⁠⁠⁠⁠⁠#regionalanesthesia⁠⁠⁠⁠⁠⁠⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠#anesthesia⁠⁠

Disclaimer: Medicine is an ever-changing science. As new research and clinical experience broaden, changes in treatment and drug therapy are required. The authors and publishers have checked with sources believed to be reliable in efforts to provide accurate information within the available or accepted standards of care. However, given the possibility of human error or changes in medical practice, neither the authors nor the publisher, nor any other party involved in the preparation of this platform warrants that the information contained herein is in every aspect accurate or complete, and they disclaim all responsibility for any errors or omissions for the results obtained from the use of the information contained in this work. Readers are advised to confirm the information contained herein with other sources. For example, readers are advised to check the product information of each drug mentioned, and that any information contained on NYSORA's Podcast is accurate.

Description: Mixing lidocaine, ropivacaine, and bicarbonate is routine in many hospitals, but is it actually safe? In this episode, we discuss the main findings from a 2026 article by Gasteiger et al. (Anesthesiology), which questions the stability, efficacy, and safety of common local anesthetic mixtures. From crystal formation to reduced block performance, we explore why combining drugs may do more harm than good, and how to rethink this everyday practice.

Read more about this on NYSORA.com.

--------------------------------------------------------- ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠

Where else to find us: Web- ⁠⁠⁠⁠⁠⁠http://www.nysora.com⁠⁠⁠⁠⁠⁠ 

Instagram- ⁠⁠⁠⁠⁠⁠instagram.com/nysora.inc/ ⁠⁠⁠⁠⁠⁠

LinkedIN- ⁠⁠⁠⁠⁠⁠linkedin.com/company/nysora-inc/⁠⁠⁠⁠⁠⁠ 

Facebook- ⁠⁠⁠⁠⁠⁠facebook.com/nysora⁠⁠⁠⁠⁠⁠ 

Twitter- ⁠⁠⁠⁠⁠⁠x.com/nysora⁠⁠⁠⁠⁠⁠ 

TikTok- ⁠⁠⁠⁠⁠⁠tiktok.com/@nysora_inc⁠⁠⁠⁠⁠⁠ 

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⁠⁠⁠⁠#nysora⁠⁠⁠⁠⁠⁠ ⁠⁠⁠⁠⁠⁠#regionalanesthesia⁠⁠⁠⁠⁠⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠#anesthesia⁠⁠

Disclaimer: Medicine is an ever-changing science. As new research and clinical experience broaden, changes in treatment and drug therapy are required. The authors and publishers have checked with sources believed to be reliable in efforts to provide accurate information within the available or accepted standards of care. However, given the possibility of human error or changes in medical practice, neither the authors nor the publisher, nor any other party involved in the preparation of this platform warrants that the information contained herein is in every aspect accurate or complete, and they disclaim all responsibility for any errors or omissions for the results obtained from the use of the information contained in this work. Readers are advised to confirm the information contained herein with other sources. For example, readers are advised to check the product information of each drug mentioned, and that any information contained on NYSORA's Podcast is accurate.

Postoperative fatigue and muscle weakness affect most surgical patients, but they’re often overlooked. In this episode, we discuss the biology behind POF and POAW, and what anesthesia and perioperative care can do to reduce their impact.

Read more about this topic on NYSORA.com.
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Where else to find us: Web- ⁠⁠⁠⁠⁠⁠⁠http://www.nysora.com⁠⁠⁠⁠⁠⁠⁠ 

Instagram- ⁠⁠⁠⁠⁠⁠⁠instagram.com/nysora.inc/ ⁠⁠⁠⁠⁠⁠⁠

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Facebook- ⁠⁠⁠⁠⁠⁠⁠facebook.com/nysora⁠⁠⁠⁠⁠⁠⁠ 

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⁠⁠⁠⁠⁠#nysora⁠⁠⁠⁠⁠⁠⁠ ⁠⁠⁠⁠⁠⁠⁠#regionalanesthesia⁠⁠⁠⁠⁠⁠⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠#anesthesia⁠⁠

Disclaimer: Medicine is an ever-changing science. As new research and clinical experience broaden, changes in treatment and drug therapy are required. The authors and publishers have checked with sources believed to be reliable in efforts to provide accurate information within the available or accepted standards of care. However, given the possibility of human error or changes in medical practice, neither the authors nor the publisher, nor any other party involved in the preparation of this platform warrants that the information contained herein is in every aspect accurate or complete, and they disclaim all responsibility for any errors or omissions for the results obtained from the use of the information contained in this work. Readers are advised to confirm the information contained herein with other sources. For example, readers are advised to check the product information of each drug mentioned, and that any information contained on NYSORA's Podcast is accurate.

A new 2025 international guideline is pushing for videolaryngoscopy to become the universal standard for tracheal intubation. In this podcast, we explore how a simple camera and screen are transforming airway management, improving team coordination, and increasing first-pass success in critical situations. We also discuss the surprising barriers to adoption, from the “paradox of expertise” to cost and training, and what this shift means for patient safety and the future of emergency medicine.

Read more about this topic on NYSORA.com.

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Where else to find us: Web- ⁠⁠⁠⁠⁠⁠http://www.nysora.com⁠⁠⁠⁠⁠⁠ 

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⁠⁠⁠⁠#nysora⁠⁠⁠⁠⁠⁠ ⁠⁠⁠⁠⁠⁠#regionalanesthesia⁠⁠⁠⁠⁠⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠#anesthesia⁠⁠

Disclaimer: Medicine is an ever-changing science. As new research and clinical experience broaden, changes in treatment and drug therapy are required. The authors and publishers have checked with sources believed to be reliable in efforts to provide accurate information within the available or accepted standards of care. However, given the possibility of human error or changes in medical practice, neither the authors nor the publisher, nor any other party involved in the preparation of this platform warrants that the information contained herein is in every aspect accurate or complete, and they disclaim all responsibility for any errors or omissions for the results obtained from the use of the information contained in this work. Readers are advised to confirm the information contained herein with other sources. For example, readers are advised to check the product information of each drug mentioned, and that any information contained on NYSORA's Podcast is accurate.

In this episode, we discuss a 2026 randomized trial comparing the PENG block and lateral quadratus lumborum block for total hip arthroplasty. Both techniques preserve mobility and perform well in the PACU, but differences emerge after discharge. We explore which block provides better pain control, reduces opioid use, and what this means for real-world recovery.

Read more about this topic on NYSORA.com.

Where else to find us: Web- ⁠⁠⁠⁠⁠http://www.nysora.com⁠⁠⁠⁠⁠ 

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⁠⁠⁠#nysora⁠⁠⁠⁠⁠ ⁠⁠⁠⁠⁠#regionalanesthesia⁠⁠⁠⁠⁠ ⁠⁠⁠⁠⁠⁠⁠⁠#anesthesia⁠⁠

Disclaimer: Medicine is an ever-changing science. As new research and clinical experience broaden, changes in treatment and drug therapy are required. The authors and publishers have checked with sources believed to be reliable in efforts to provide accurate information within the available or accepted standards of care. However, given the possibility of human error or changes in medical practice, neither the authors nor the publisher, nor any other party involved in the preparation of this platform warrants that the information contained herein is in every aspect accurate or complete, and they disclaim all responsibility for any errors or omissions for the results obtained from the use of the information contained in this work. Readers are advised to confirm the information contained herein with other sources. For example, readers are advised to check the product information of each drug mentioned, and that any information contained on NYSORA's Podcast is accurate.

A new BJA trial compares paravertebral block (PVB) and PEFB for rib fracture pain. While PEFB matches early pain control, it fails in durability, leading to more rescue interventions. PVB, though more complex, better restores cough and respiratory function.

The key shift: stop focusing on pain at rest and start treating for function.

Where else to find us: Web- ⁠⁠⁠⁠http://www.nysora.com⁠⁠⁠⁠ 

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⁠⁠#nysora⁠⁠⁠⁠ ⁠⁠⁠⁠#regionalanesthesia⁠⁠⁠⁠ ⁠⁠⁠⁠⁠⁠#anesthesia⁠⁠

Disclaimer: Medicine is an ever-changing science. As new research and clinical experience broaden, changes in treatment and drug therapy are required. The authors and publishers have checked with sources believed to be reliable in efforts to provide accurate information within the available or accepted standards of care. However, given the possibility of human error or changes in medical practice, neither the authors nor the publisher, nor any other party involved in the preparation of this platform warrants that the information contained herein is in every aspect accurate or complete, and they disclaim all responsibility for any errors or omissions for the results obtained from the use of the information contained in this work. Readers are advised to confirm the information contained herein with other sources. For example, readers are advised to check the product information of each drug mentioned, and that any information contained on NYSORA's Podcast is accurate.

One in three births in the U.S. occurs by cesarean delivery.
But when it comes to neonatal outcomes, does the anesthetic technique matter? A new meta-analysis of 36 randomized trials involving more than 3,400 neonates compared regional and general anesthesia. This episode reviews the key findings and explores their implications for daily clinical practice.

Where else to find us: Web- ⁠⁠⁠⁠http://www.nysora.com⁠⁠⁠⁠ 

Instagram- ⁠⁠⁠⁠instagram.com/nysora.inc/ ⁠⁠⁠⁠

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⁠⁠#nysora⁠⁠⁠⁠ ⁠⁠⁠⁠#regionalanesthesia⁠⁠⁠⁠ ⁠⁠⁠⁠⁠⁠#anesthesia⁠⁠

Disclaimer: Medicine is an ever-changing science. As new research and clinical experience broaden, changes in treatment and drug therapy are required. The authors and publishers have checked with sources believed to be reliable in efforts to provide accurate information within the available or accepted standards of care. However, given the possibility of human error or changes in medical practice, neither the authors nor the publisher, nor any other party involved in the preparation of this platform warrants that the information contained herein is in every aspect accurate or complete, and they disclaim all responsibility for any errors or omissions for the results obtained from the use of the information contained in this work. Readers are advised to confirm the information contained herein with other sources. For example, readers are advised to check the product information of each drug mentioned, and that any information contained on NYSORA's Podcast is accurate.

Airway management in thoracic anesthesia is evolving rapidly. New guidelines from the EACTAIC Thoracic Group highlight a shift toward structured risk stratification, advanced imaging, video-assisted devices, and emerging digital technologies. In this episode, we explore what’s changed, what’s coming next, and what thoracic anesthesiologists should be doing today.

Where else to find us: Web- ⁠⁠⁠http://www.nysora.com⁠⁠⁠ 

Instagram- ⁠⁠⁠instagram.com/nysora.inc/ ⁠⁠⁠

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⁠#nysora⁠⁠⁠ ⁠⁠⁠#regionalanesthesia⁠⁠⁠ ⁠⁠⁠⁠#anesthesia⁠⁠

Disclaimer: Medicine is an ever-changing science. As new research and clinical experience broaden, changes in treatment and drug therapy are required. The authors and publishers have checked with sources believed to be reliable in efforts to provide accurate information within the available or accepted standards of care. However, given the possibility of human error or changes in medical practice, neither the authors nor the publisher, nor any other party involved in the preparation of this platform warrants that the information contained herein is in every aspect accurate or complete, and they disclaim all responsibility for any errors or omissions for the results obtained from the use of the information contained in this work. Readers are advised to confirm the information contained herein with other sources. For example, readers are advised to check the product information of each drug mentioned, and that any information contained on NYSORA's Podcast is accurate.

Neuraxial anesthesia has long been associated with better outcomes in total hip and knee arthroplasty—but does that advantage still hold in modern practice? In this episode, we discuss the main findings from new large-scale data showing that neuraxial anesthesia continues to reduce perioperative complications, even as anesthesia techniques and patient populations evolve.

Where else to find us:
Web- ⁠⁠http://www.nysora.com⁠⁠ 

Instagram- ⁠⁠instagram.com/nysora.inc/ ⁠⁠

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Facebook- ⁠⁠facebook.com/nysora⁠⁠ 

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TikTok- ⁠⁠tiktok.com/@nysora_inc⁠⁠ 

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#nysora⁠⁠ ⁠⁠#regionalanesthesia⁠⁠ ⁠⁠#anesthesia⁠⁠

Disclaimer: Medicine is an ever-changing science. As new research and clinical experience broaden, changes in treatment and drug therapy are required. The authors and publishers have checked with sources believed to be reliable in efforts to provide accurate information within the available or accepted standards of care. However, given the possibility of human error or changes in medical practice, neither the authors nor the publisher, nor any other party involved in the preparation of this platform warrants that the information contained herein is in every aspect accurate or complete, and they disclaim all responsibility for any errors or omissions for the results obtained from the use of the information contained in this work. Readers are advised to confirm the information contained herein with other sources. For example, readers are advised to check the product information of each drug mentioned, and that any information contained on NYSORA's Podcast is accurate.

Motor-sparing regional anesthesia is the backbone of modern total knee arthroplasty analgesia. But posterior knee pain remains a blind spot. In this episode, we discuss the main findings from  new randomized trial data on whether adding a popliteal plexus block to a femoral triangle block actually moves the needle, on opioids, pain, and mobility.

Where else to find us:
Web- ⁠⁠http://www.nysora.com⁠⁠ 

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#nysora⁠⁠ ⁠⁠#regionalanesthesia⁠⁠ ⁠⁠#anesthesia⁠⁠

Disclaimer: Medicine is an ever-changing science. As new research and clinical experience broaden, changes in treatment and drug therapy are required. The authors and publishers have checked with sources believed to be reliable in efforts to provide accurate information within the available or accepted standards of care. However, given the possibility of human error or changes in medical practice, neither the authors nor the publisher, nor any other party involved in the preparation of this platform warrants that the information contained herein is in every aspect accurate or complete, and they disclaim all responsibility for any errors or omissions for the results obtained from the use of the information contained in this work. Readers are advised to confirm the information contained herein with other sources. For example, readers are advised to check the product information of each drug mentioned, and that any information contained on NYSORA's Podcast is accurate.