In this episode of UPDATES IN ANESTHESIOLOGY, Dr. Hadzic breaks down a landmark study by Garcia-Casanovas et al., published in Anesthesiology (July 2025), involving over 30,000 joint arthroplasty patients across 43 hospitals. The study shows that higher adherence to patient blood management (PBM) guidelines isn't just about fewer transfusions; it leads to fewer complications, shorter hospital stays, and better outcomes across the board. Tune in to hear why delivering PBM as a bundled strategy, not piecemeal, is key, and walk away with actionable tips to improve patient safety and performance in your own practice.\

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Disclaimer: Medicine is an ever-changing science. As new research and clinical experience broaden, changes in treatment and drug therapy are required. The authors and publishers have checked with sources believed to be reliable in efforts to provide accurate information within the available or accepted standards of care. However, given the possibility of human error or changes in medical practice, neither the authors nor the publisher, nor any other party involved in the preparation of this platform warrants that the information contained herein is in every aspect accurate or complete, and they disclaim all responsibility for any errors or omissions for the results obtained from the use of the information contained in this work. Readers are advised to confirm the information contained herein with other sources. For example, readers are advised to check the product information of each drug mentioned, and that any information contained on NYSORA's Podcast is accurate.

In this episode of Updates in Anesthesiology, Dr. Hadzic reviews the newly published 2025 international clinical practice guidelines on platelet transfusion, co-led by Dr. Ryan Metcalf from the University of Utah and Dr. Simon Stanworth from Oxford, and published in JAMA. Based on evidence from over 30 studies, these guidelines recommend restrictive platelet transfusion thresholds in both adult and pediatric populations, advocating for transfusions only when platelet counts are critically low in specific scenarios. The goal? Minimize unnecessary transfusions, reduce patient harm, and conserve resources without increasing bleeding or mortality.

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#nysora⁠⁠ ⁠⁠#regionalanesthesia⁠⁠ ⁠⁠#anesthesia⁠⁠

Disclaimer: Medicine is an ever-changing science. As new research and clinical experience broaden, changes in treatment and drug therapy are required. The authors and publishers have checked with sources believed to be reliable in efforts to provide accurate information within the available or accepted standards of care. However, given the possibility of human error or changes in medical practice, neither the authors nor the publisher, nor any other party involved in the preparation of this platform warrants that the information contained herein is in every aspect accurate or complete, and they disclaim all responsibility for any errors or omissions for the results obtained from the use of the information contained in this work. Readers are advised to confirm the information contained herein with other sources. For example, readers are advised to check the product information of each drug mentioned, and that any information contained on NYSORA's Podcast is accurate.

In this episode of Updates in Anesthesiology, Dr. Hadzic breaks down the results from the PRECISION study published in Anesthesiology (2025). Led by Dr. Cui and colleagues, this prospective trial reveals that nearly 1 in 9 older patients undergoing noncardiac surgery, especially neurosurgical, experience covert strokes detectable only by MRI. These “silent” strokes double the risk of postoperative delirium and long-term cognitive decline. Tune in to hear what this means for perioperative care, how to identify patients at risk, and actionable strategies to protect brain health after surgery.

Where else to find us:
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#nysora⁠⁠ ⁠⁠#regionalanesthesia⁠⁠ ⁠⁠#anesthesia⁠⁠

Disclaimer: Medicine is an ever-changing science. As new research and clinical experience broaden, changes in treatment and drug therapy are required. The authors and publishers have checked with sources believed to be reliable in efforts to provide accurate information within the available or accepted standards of care. However, given the possibility of human error or changes in medical practice, neither the authors nor the publisher, nor any other party involved in the preparation of this platform warrants that the information contained herein is in every aspect accurate or complete, and they disclaim all responsibility for any errors or omissions for the results obtained from the use of the information contained in this work. Readers are advised to confirm the information contained herein with other sources. For example, readers are advised to check the product information of each drug mentioned, and that any information contained on NYSORA's Podcast is accurate.

In this episode of Updates in Anesthesiology, Dr. Hadzic breaks down the largest real-world study to date comparing the environmental impact of general anesthesia strategies. With over 35,000 cases analyzed, discover why TIVA with propofol has emerged as the lowest carbon emitter, outperforming even optimized sevoflurane techniques. We’ll explore the GHG numbers, plastic waste concerns, and clinical outcomes, and conclude with practical tips to make your OR practice more sustainable without compromising patient care.

Where else to find us:
Web- ⁠⁠http://www.nysora.com⁠⁠ 

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#nysora⁠⁠ ⁠⁠#regionalanesthesia⁠⁠ ⁠⁠#anesthesia⁠⁠

Disclaimer: Medicine is an ever-changing science. As new research and clinical experience broaden, changes in treatment and drug therapy are required. The authors and publishers have checked with sources believed to be reliable in efforts to provide accurate information within the available or accepted standards of care. However, given the possibility of human error or changes in medical practice, neither the authors nor the publisher, nor any other party involved in the preparation of this platform warrants that the information contained herein is in every aspect accurate or complete, and they disclaim all responsibility for any errors or omissions for the results obtained from the use of the information contained in this work. Readers are advised to confirm the information contained herein with other sources. For example, readers are advised to check the product information of each drug mentioned, and that any information contained on NYSORA's Podcast is accurate.

In this episode of UPDATES IN ANESTHESIOLOGY, Dr. Hadzic discusses a new international consensus on apnoeic oxygenation using high-flow nasal oxygen (HFNO) during laryngotracheal surgery. Featuring insights from a newly published 19-item safety checklist in the European Journal of Anaesthesiology, we break down what every clinician needs to know, from patient selection to post-op care, to improve safety and streamline multidisciplinary workflows. Whether you're already using THRIVE or just curious about best practices, this episode gives you the practical takeaways to elevate your airway game.

Where else to find us:
Web- ⁠⁠http://www.nysora.com⁠⁠ 

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--------------------------------------------------------- ⁠⁠

#nysora⁠⁠ ⁠⁠#regionalanesthesia⁠⁠ ⁠⁠#anesthesia⁠⁠

Disclaimer: Medicine is an ever-changing science. As new research and clinical experience broaden, changes in treatment and drug therapy are required. The authors and publishers have checked with sources believed to be reliable in efforts to provide accurate information within the available or accepted standards of care. However, given the possibility of human error or changes in medical practice, neither the authors nor the publisher, nor any other party involved in the preparation of this platform warrants that the information contained herein is in every aspect accurate or complete, and they disclaim all responsibility for any errors or omissions for the results obtained from the use of the information contained in this work. Readers are advised to confirm the information contained herein with other sources. For example, readers are advised to check the product information of each drug mentioned, and that any information contained on NYSORA's Podcast is accurate.

 In this episode of Updates in Anesthesiology, Dr. Hadzic unpacks the FRAIL-HIP study published in JAMA Surgery, which challenges the routine use of surgery for proximal femoral fractures in frail, institutionalized older adults. You'll hear how nonoperative management, guided by a structured shared decision-making process, can lead to comparable quality of life, fewer adverse events, and even a more dignified dying experience. Tune in to discover how this paradigm shift could reshape your approach to surgical decisions in end-of-life care.

Where else to find us:
Web- ⁠⁠http://www.nysora.com⁠⁠ 

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--------------------------------------------------------- ⁠⁠

#nysora⁠⁠ ⁠⁠#regionalanesthesia⁠⁠ ⁠⁠#anesthesia⁠⁠

Disclaimer: Medicine is an ever-changing science. As new research and clinical experience broaden, changes in treatment and drug therapy are required. The authors and publishers have checked with sources believed to be reliable in efforts to provide accurate information within the available or accepted standards of care. However, given the possibility of human error or changes in medical practice, neither the authors nor the publisher, nor any other party involved in the preparation of this platform warrants that the information contained herein is in every aspect accurate or complete, and they disclaim all responsibility for any errors or omissions for the results obtained from the use of the information contained in this work. Readers are advised to confirm the information contained herein with other sources. For example, readers are advised to check the product information of each drug mentioned, and that any information contained on NYSORA's Podcast is accurate.

In this episode of Updates in Anesthesiology, Dr. Hadzic breaks down the latest evidence comparing ketamine, etomidate, and propofol for tracheal intubation in critically ill patients. Drawing from a 2025 review in Critical Care Medicine, we explore why ketamine is emerging as the safest and most reliable option, while etomidate shows a potential mortality risk, and propofol continues to raise red flags for cardiovascular instability. Get the evidence, the implications, and the practical takeaways, all in one focused episode.

Where else to find us:
Web- ⁠⁠http://www.nysora.com⁠⁠ 

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--------------------------------------------------------- ⁠⁠

#nysora⁠⁠ ⁠⁠#regionalanesthesia⁠⁠ ⁠⁠#anesthesia⁠⁠

Disclaimer: Medicine is an ever-changing science. As new research and clinical experience broaden, changes in treatment and drug therapy are required. The authors and publishers have checked with sources believed to be reliable in efforts to provide accurate information within the available or accepted standards of care. However, given the possibility of human error or changes in medical practice, neither the authors nor the publisher, nor any other party involved in the preparation of this platform warrants that the information contained herein is in every aspect accurate or complete, and they disclaim all responsibility for any errors or omissions for the results obtained from the use of the information contained in this work. Readers are advised to confirm the information contained herein with other sources. For example, readers are advised to check the product information of each drug mentioned, and that any information contained on NYSORA's Podcast is accurate.

In this episode of Updates in Anesthesiology, Dr. Hadzic explores groundbreaking findings from Chotinaruemol and colleagues, published in the British Journal of Anaesthesia (2025), revealing how dexmedetomidine may do more than sedate. It could protect the kidneys from ischemia-reperfusion injury. From cellular survival pathways to improved surgical outcomes, we break down how DEX works, when it works best, and what this could mean for high-risk surgical patients. Stay tuned for actionable insights you can take straight to the OR.

Where else to find us:
Web- ⁠⁠http://www.nysora.com⁠⁠ 

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#nysora⁠⁠ ⁠⁠#regionalanesthesia⁠⁠ ⁠⁠#anesthesia⁠⁠

Disclaimer: Medicine is an ever-changing science. As new research and clinical experience broaden, changes in treatment and drug therapy are required. The authors and publishers have checked with sources believed to be reliable in efforts to provide accurate information within the available or accepted standards of care. However, given the possibility of human error or changes in medical practice, neither the authors nor the publisher, nor any other party involved in the preparation of this platform warrants that the information contained herein is in every aspect accurate or complete, and they disclaim all responsibility for any errors or omissions for the results obtained from the use of the information contained in this work. Readers are advised to confirm the information contained herein with other sources. For example, readers are advised to check the product information of each drug mentioned, and that any information contained on NYSORA's Podcast is accurate.

In this episode, Dr. Hadzic discusses the CDC's May 2025 nationwide alert on bloodstream infections linked to non-sterile, multi-use ultrasound gel. Learn how this outbreak unfolded, what it means for ultrasound-guided procedures, and why sterile gel and validated probe covers—like EZCOVER®—are now essential for every percutaneous procedure. Practical, evidence-based takeaways to help you enhance infection control and patient safety in your daily practice.

Where else to find us:
Web- ⁠⁠http://www.nysora.com⁠⁠ 

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--------------------------------------------------------- ⁠⁠

#nysora⁠⁠ ⁠⁠#regionalanesthesia⁠⁠ ⁠⁠#anesthesia⁠⁠

Disclaimer: Medicine is an ever-changing science. As new research and clinical experience broaden, changes in treatment and drug therapy are required. The authors and publishers have checked with sources believed to be reliable in efforts to provide accurate information within the available or accepted standards of care. However, given the possibility of human error or changes in medical practice, neither the authors nor the publisher, nor any other party involved in the preparation of this platform warrants that the information contained herein is in every aspect accurate or complete, and they disclaim all responsibility for any errors or omissions for the results obtained from the use of the information contained in this work. Readers are advised to confirm the information contained herein with other sources. For example, readers are advised to check the product information of each drug mentioned, and that any information contained on NYSORA's Podcast is accurate.

In this episode of Updates in Anesthesiology, Dr. Hadzic explores a groundbreaking study from Columbia University, published in the British Journal of Anaesthesia (2025), revealing that children who require mechanical ventilation during surgery face nearly double the risk of developing neurodevelopmental and behavioral disorders after discharge. Tune in to learn what factors may drive this association, why longer ventilation matters, and how we can act early to protect young patients' futures.

Where else to find us:
Web- ⁠⁠http://www.nysora.com⁠⁠ 

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--------------------------------------------------------- ⁠⁠

#nysora⁠⁠ ⁠⁠#regionalanesthesia⁠⁠ ⁠⁠#anesthesia⁠⁠

Disclaimer: Medicine is an ever-changing science. As new research and clinical experience broaden, changes in treatment and drug therapy are required. The authors and publishers have checked with sources believed to be reliable in efforts to provide accurate information within the available or accepted standards of care. However, given the possibility of human error or changes in medical practice, neither the authors nor the publisher, nor any other party involved in the preparation of this platform warrants that the information contained herein is in every aspect accurate or complete, and they disclaim all responsibility for any errors or omissions for the results obtained from the use of the information contained in this work. Readers are advised to confirm the information contained herein with other sources. For example, readers are advised to check the product information of each drug mentioned, and that any information contained on NYSORA's Podcast is accurate.