A 2025 Anesthesiology meta-analysis shows that the best pain control after total hip arthroplasty comes from combining regional anesthesia with local infiltration analgesia (LIA). While LIA alone is effective, adding a quadratus lumborum or pericapsular nerve group (PENG) block significantly improves pain relief, reduces opioid use, and preserves mobility. The takeaway: stop choosing between techniques — regional + local is the new gold standard for hip surgery analgesia.

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Disclaimer: Medicine is an ever-changing science. As new research and clinical experience broaden, changes in treatment and drug therapy are required. The authors and publishers have checked with sources believed to be reliable in efforts to provide accurate information within the available or accepted standards of care. However, given the possibility of human error or changes in medical practice, neither the authors nor the publisher, nor any other party involved in the preparation of this platform warrants that the information contained herein is in every aspect accurate or complete, and they disclaim all responsibility for any errors or omissions for the results obtained from the use of the information contained in this work. Readers are advised to confirm the information contained herein with other sources. For example, readers are advised to check the product information of each drug mentioned, and that any information contained on NYSORA's Podcast is accurate.

In this episode of Updates in Anesthesiology, Dr. Hadzic unpacks a landmark 2025 study, which challenges the long-held belief that intraoperative hypotension (MAP < 65 mm Hg) contributes to postoperative delirium in older adults. With nearly 40,000 patients analyzed and no association found, it’s time to rethink reflexively chasing MAP thresholds. Tune in to hear why blood pressure might not be the villain we thought, and what really matters for preventing POD.

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#nysora⁠⁠ ⁠⁠#regionalanesthesia⁠⁠ ⁠⁠#anesthesia⁠⁠

Disclaimer: Medicine is an ever-changing science. As new research and clinical experience broaden, changes in treatment and drug therapy are required. The authors and publishers have checked with sources believed to be reliable in efforts to provide accurate information within the available or accepted standards of care. However, given the possibility of human error or changes in medical practice, neither the authors nor the publisher, nor any other party involved in the preparation of this platform warrants that the information contained herein is in every aspect accurate or complete, and they disclaim all responsibility for any errors or omissions for the results obtained from the use of the information contained in this work. Readers are advised to confirm the information contained herein with other sources. For example, readers are advised to check the product information of each drug mentioned, and that any information contained on NYSORA's Podcast is accurate.

In this episode of Updates in Anesthesiology, Dr. Hadzic delves into a 2025 study, which analyzed over 53,000 surgical cases. The key finding? Neuromuscular blockers increase the risk of postoperative delirium in older adults, unless they’re properly reversed. Whether you use sugammadex or neostigmine, reversal agents significantly reduce this risk. Tune in to hear what this means for your clinical practice and how small changes in perioperative management can make a significant impact on cognitive outcomes.

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#nysora⁠⁠ ⁠⁠#regionalanesthesia⁠⁠ ⁠⁠#anesthesia⁠⁠

Disclaimer: Medicine is an ever-changing science. As new research and clinical experience broaden, changes in treatment and drug therapy are required. The authors and publishers have checked with sources believed to be reliable in efforts to provide accurate information within the available or accepted standards of care. However, given the possibility of human error or changes in medical practice, neither the authors nor the publisher, nor any other party involved in the preparation of this platform warrants that the information contained herein is in every aspect accurate or complete, and they disclaim all responsibility for any errors or omissions for the results obtained from the use of the information contained in this work. Readers are advised to confirm the information contained herein with other sources. For example, readers are advised to check the product information of each drug mentioned, and that any information contained on NYSORA's Podcast is accurate.

In this episode of Updates in Anesthesiology, Dr. Hadzic unpacks the latest evidence on pharmacologic agents for perioperative cardioprotection in noncardiac surgery. From beta-blockers and statins to the evolving debate around RAAS inhibitors and aspirin, we cover what works, what doesn’t, and what’s still unclear. Plus, we discuss whether tighter blood pressure control or postoperative therapy intensification makes a difference. Tune in for practical, evidence-based takeaways to improve cardiac outcomes in your surgical patients.

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#nysora⁠⁠ ⁠⁠#regionalanesthesia⁠⁠ ⁠⁠#anesthesia⁠⁠

Disclaimer: Medicine is an ever-changing science. As new research and clinical experience broaden, changes in treatment and drug therapy are required. The authors and publishers have checked with sources believed to be reliable in efforts to provide accurate information within the available or accepted standards of care. However, given the possibility of human error or changes in medical practice, neither the authors nor the publisher, nor any other party involved in the preparation of this platform warrants that the information contained herein is in every aspect accurate or complete, and they disclaim all responsibility for any errors or omissions for the results obtained from the use of the information contained in this work. Readers are advised to confirm the information contained herein with other sources. For example, readers are advised to check the product information of each drug mentioned, and that any information contained on NYSORA's Podcast is accurate.

In this episode, Dr. Hadzic discusses the main findings from a new study from the British Journal of Anaesthesia (2025). The study reported that 1 in 4 children having noncardiac surgery has preoperative anemia, and that both anemia and transfusion independently, and especially together, increase 30-day mortality and complications. Despite strong global guidelines for blood management and anesthesia care in adults, pediatric blood management remains under-implemented. Learn how this data can transform your pre-op protocols, and what steps you can take right now to improve pediatric surgical outcomes.

Where else to find us:
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#nysora⁠⁠ ⁠⁠#regionalanesthesia⁠⁠ ⁠⁠#anesthesia⁠⁠

Disclaimer: Medicine is an ever-changing science. As new research and clinical experience broaden, changes in treatment and drug therapy are required. The authors and publishers have checked with sources believed to be reliable in efforts to provide accurate information within the available or accepted standards of care. However, given the possibility of human error or changes in medical practice, neither the authors nor the publisher, nor any other party involved in the preparation of this platform warrants that the information contained herein is in every aspect accurate or complete, and they disclaim all responsibility for any errors or omissions for the results obtained from the use of the information contained in this work. Readers are advised to confirm the information contained herein with other sources. For example, readers are advised to check the product information of each drug mentioned, and that any information contained on NYSORA's Podcast is accurate.

In this episode of UPDATES IN ANESTHESIOLOGY, Dr. Hadzic reviews a 2025 paper from Anesthesiology on managing obstetric anesthesia for patients with diabetes. From prelabor planning to postpartum glucose shifts, this episode covers everything you need to provide safe and effective anesthesia care for this growing population of high-risk parturients.

Where else to find us:
Web- ⁠⁠http://www.nysora.com⁠⁠ 

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#nysora⁠⁠ ⁠⁠#regionalanesthesia⁠⁠ ⁠⁠#anesthesia⁠⁠

Disclaimer: Medicine is an ever-changing science. As new research and clinical experience broaden, changes in treatment and drug therapy are required. The authors and publishers have checked with sources believed to be reliable in efforts to provide accurate information within the available or accepted standards of care. However, given the possibility of human error or changes in medical practice, neither the authors nor the publisher, nor any other party involved in the preparation of this platform warrants that the information contained herein is in every aspect accurate or complete, and they disclaim all responsibility for any errors or omissions for the results obtained from the use of the information contained in this work. Readers are advised to confirm the information contained herein with other sources. For example, readers are advised to check the product information of each drug mentioned, and that any information contained on NYSORA's Podcast is accurate.

 In this episode of the NYSORA Podcast: Updates in Anesthesiology, Dr. Hadzic breaks down what anesthesiologists need to know about using AI in clinical practice. We cover recent studies showing where AI like ChatGPT performs well (like data analysis) — and where it can be risky, especially in complex patient cases. You’ll also learn how NYSORA’s Anesthesia Assistant App, powered by Maia, gives you fast, reliable answers at the bedside—built on peer-reviewed content and reviewed by experts.
 What you’ll get:

• When to trust AI—and when not to
• How NYSORA’s app supports safe, informed decisions
• Real tips you can apply in practice today

Where else to find us:
Web- ⁠⁠http://www.nysora.com⁠⁠ 

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#nysora⁠⁠ ⁠⁠#regionalanesthesia⁠⁠ ⁠⁠#anesthesia⁠⁠

Disclaimer: Medicine is an ever-changing science. As new research and clinical experience broaden, changes in treatment and drug therapy are required. The authors and publishers have checked with sources believed to be reliable in efforts to provide accurate information within the available or accepted standards of care. However, given the possibility of human error or changes in medical practice, neither the authors nor the publisher, nor any other party involved in the preparation of this platform warrants that the information contained herein is in every aspect accurate or complete, and they disclaim all responsibility for any errors or omissions for the results obtained from the use of the information contained in this work. Readers are advised to confirm the information contained herein with other sources. For example, readers are advised to check the product information of each drug mentioned, and that any information contained on NYSORA's Podcast is accurate.

In this episode of UPDATES IN ANESTHESIOLOGY, Dr. Hadzic unpacks Hepatopulmonary Syndrome (HPS), a frequently missed but life-threatening complication of chronic liver disease. Drawing on a 2025 review from Current Opinion in Anesthesiology, we cover the mechanisms of HPS, key diagnostic clues like platypnea and orthodeoxia, and why liver transplantation remains the only curative therapy. You’ll also learn why MELD exception points are reshaping transplant access, the limits of emerging drug therapies, and practical anesthesia management tips for these challenging patients.

Where else to find us:
Web- ⁠⁠http://www.nysora.com⁠⁠ 

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#nysora⁠⁠ ⁠⁠#regionalanesthesia⁠⁠ ⁠⁠#anesthesia⁠⁠

Disclaimer: Medicine is an ever-changing science. As new research and clinical experience broaden, changes in treatment and drug therapy are required. The authors and publishers have checked with sources believed to be reliable in efforts to provide accurate information within the available or accepted standards of care. However, given the possibility of human error or changes in medical practice, neither the authors nor the publisher, nor any other party involved in the preparation of this platform warrants that the information contained herein is in every aspect accurate or complete, and they disclaim all responsibility for any errors or omissions for the results obtained from the use of the information contained in this work. Readers are advised to confirm the information contained herein with other sources. For example, readers are advised to check the product information of each drug mentioned, and that any information contained on NYSORA's Podcast is accurate.

In this episode of NYSORA’s Updates in Anesthesiology, Dr. Hadzic breaks down the 2024 ESAIC guidelines on postoperative delirium (POD) in adults. Discover the latest evidence on risk factors, why inflammation, not just anesthesia, may be the real culprit, and why multicomponent nonpharmacological strategies are your best bet. Learn what works, what doesn’t, and how to protect your patients from this common yet preventable complication. Stay ahead of the curve with this essential update for every perioperative clinician.

Where else to find us:
Web- ⁠⁠http://www.nysora.com⁠⁠ 

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#nysora⁠⁠ ⁠⁠#regionalanesthesia⁠⁠ ⁠⁠#anesthesia⁠⁠

Disclaimer: Medicine is an ever-changing science. As new research and clinical experience broaden, changes in treatment and drug therapy are required. The authors and publishers have checked with sources believed to be reliable in efforts to provide accurate information within the available or accepted standards of care. However, given the possibility of human error or changes in medical practice, neither the authors nor the publisher, nor any other party involved in the preparation of this platform warrants that the information contained herein is in every aspect accurate or complete, and they disclaim all responsibility for any errors or omissions for the results obtained from the use of the information contained in this work. Readers are advised to confirm the information contained herein with other sources. For example, readers are advised to check the product information of each drug mentioned, and that any information contained on NYSORA's Podcast is accurate.

In this episode, Dr. Hadzic unpacks a 2025 British Journal of Anaesthesia systematic review led by Dr. Grant and colleagues, exploring the hidden dangers of common analgesics, opioids, NSAIDs, and gabapentinoids in patients with multiple chronic conditions. With over 2.6 million patients studied, the findings reveal clear red flags and critical evidence gaps. Tune in for practical insights, risk-reduction strategies, and what this means for your everyday prescribing decisions.

Where else to find us:
Web- ⁠⁠http://www.nysora.com⁠⁠ 

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#nysora⁠⁠ ⁠⁠#regionalanesthesia⁠⁠ ⁠⁠#anesthesia⁠⁠

Disclaimer: Medicine is an ever-changing science. As new research and clinical experience broaden, changes in treatment and drug therapy are required. The authors and publishers have checked with sources believed to be reliable in efforts to provide accurate information within the available or accepted standards of care. However, given the possibility of human error or changes in medical practice, neither the authors nor the publisher, nor any other party involved in the preparation of this platform warrants that the information contained herein is in every aspect accurate or complete, and they disclaim all responsibility for any errors or omissions for the results obtained from the use of the information contained in this work. Readers are advised to confirm the information contained herein with other sources. For example, readers are advised to check the product information of each drug mentioned, and that any information contained on NYSORA's Podcast is accurate.