In this episode of Updates in Anesthesiology, Dr. Hadzic unpacks the latest evidence on sugammadex-induced anaphylaxis from the 2025 Anesthesiology review by Dr. Savic and colleagues. We explore the benefits that make sugammadex the preferred reversal agent over neostigmine, and the rare but serious risk of hypersensitivity reactions. You'll learn about proposed mechanisms, diagnostic pitfalls, global incidence data, and what this all means for your daily anesthesia practice. Stay informed, stay prepared, and make safer clinical choices.

Where else to find us:
Web- ⁠⁠http://www.nysora.com⁠⁠ 

Instagram- ⁠⁠instagram.com/nysora.inc/ ⁠⁠

LinkedIN- ⁠⁠linkedin.com/company/nysora-inc/⁠⁠ 

Facebook- ⁠⁠facebook.com/nysora⁠⁠ 

Twitter- ⁠⁠x.com/nysora⁠⁠ 

TikTok- ⁠⁠tiktok.com/@nysora_inc⁠⁠ 

--------------------------------------------------------- ⁠⁠

#nysora⁠⁠ ⁠⁠#regionalanesthesia⁠⁠ ⁠⁠#anesthesia⁠⁠

Disclaimer: Medicine is an ever-changing science. As new research and clinical experience broaden, changes in treatment and drug therapy are required. The authors and publishers have checked with sources believed to be reliable in efforts to provide accurate information within the available or accepted standards of care. However, given the possibility of human error or changes in medical practice, neither the authors nor the publisher, nor any other party involved in the preparation of this platform warrants that the information contained herein is in every aspect accurate or complete, and they disclaim all responsibility for any errors or omissions for the results obtained from the use of the information contained in this work. Readers are advised to confirm the information contained herein with other sources. For example, readers are advised to check the product information of each drug mentioned, and that any information contained on NYSORA's Podcast is accurate.

In this episode of Updates in Anesthesiology, Dr. Hadzic reviews a double-blind RCT from Anesthesia & Analgesia (March 2025) led by Dr. Ajetunmobi and colleagues. The study compared sugammadex and neostigmine for neuromuscular blockade reversal in morbidly obese patients with OSA undergoing bariatric surgery. Despite sugammadex’s pharmacologic advantages, the study found no significant difference in OR discharge times between the agents. Join us as we analyze the data, explore potential explanations, and discuss the practical implications for your anesthesia practice.

Where else to find us:
Web- ⁠⁠http://www.nysora.com⁠⁠ 

Instagram- ⁠⁠instagram.com/nysora.inc/ ⁠⁠

LinkedIN- ⁠⁠linkedin.com/company/nysora-inc/⁠⁠ 

Facebook- ⁠⁠facebook.com/nysora⁠⁠ 

Twitter- ⁠⁠x.com/nysora⁠⁠ 

TikTok- ⁠⁠tiktok.com/@nysora_inc⁠⁠ 

--------------------------------------------------------- ⁠⁠

#nysora⁠⁠ ⁠⁠#regionalanesthesia⁠⁠ ⁠⁠#anesthesia⁠⁠

Disclaimer: Medicine is an ever-changing science. As new research and clinical experience broaden, changes in treatment and drug therapy are required. The authors and publishers have checked with sources believed to be reliable in efforts to provide accurate information within the available or accepted standards of care. However, given the possibility of human error or changes in medical practice, neither the authors nor the publisher, nor any other party involved in the preparation of this platform warrants that the information contained herein is in every aspect accurate or complete, and they disclaim all responsibility for any errors or omissions for the results obtained from the use of the information contained in this work. Readers are advised to confirm the information contained herein with other sources. For example, readers are advised to check the product information of each drug mentioned, and that any information contained on NYSORA's Podcast is accurate.

In this episode of Updates in Anesthesiology, Dr. Hadzic discusses  a 2025 study by Corpman et al. evaluating ChatGPT-4, Bard, and other AI chatbots as decision support tools in regional anesthesia. The findings? AI is getting smarter, but it still makes major clinical errors. Enter MAIA, NYSORA’s purpose-built AI assistant, designed by anesthesiologists to bridge the gap between innovation and safe practice. Tune in to hear why general AI tools may not be ready for primetime—and how MAIA sets a new standard in anesthesia decision support.

Where else to find us:
Web- ⁠⁠http://www.nysora.com⁠⁠ 

Instagram- ⁠⁠instagram.com/nysora.inc/ ⁠⁠

LinkedIN- ⁠⁠linkedin.com/company/nysora-inc/⁠⁠ 

Facebook- ⁠⁠facebook.com/nysora⁠⁠ 

Twitter- ⁠⁠x.com/nysora⁠⁠ 

TikTok- ⁠⁠tiktok.com/@nysora_inc⁠⁠ 

--------------------------------------------------------- ⁠⁠

#nysora⁠⁠ ⁠⁠#regionalanesthesia⁠⁠ ⁠⁠#anesthesia⁠⁠

Disclaimer: Medicine is an ever-changing science. As new research and clinical experience broaden, changes in treatment and drug therapy are required. The authors and publishers have checked with sources believed to be reliable in efforts to provide accurate information within the available or accepted standards of care. However, given the possibility of human error or changes in medical practice, neither the authors nor the publisher, nor any other party involved in the preparation of this platform warrants that the information contained herein is in every aspect accurate or complete, and they disclaim all responsibility for any errors or omissions for the results obtained from the use of the information contained in this work. Readers are advised to confirm the information contained herein with other sources. For example, readers are advised to check the product information of each drug mentioned, and that any information contained on NYSORA's Podcast is accurate.

 In this episode of UPDATES IN ANESTHESIOLOGY, Dr. Hadzic breaks down a landmark study by Garcia-Casanovas et al., published in Anesthesiology (July 2025), involving over 30,000 joint arthroplasty patients across 43 hospitals. The study shows that higher adherence to patient blood management (PBM) guidelines isn't just about fewer transfusions; it leads to fewer complications, shorter hospital stays, and better outcomes across the board. Tune in to hear why delivering PBM as a bundled strategy, not piecemeal, is key, and walk away with actionable tips to improve patient safety and performance in your own practice.\

Where else to find us:
Web- ⁠⁠http://www.nysora.com⁠⁠ 

Instagram- ⁠⁠instagram.com/nysora.inc/ ⁠⁠

LinkedIN- ⁠⁠linkedin.com/company/nysora-inc/⁠⁠ 

Facebook- ⁠⁠facebook.com/nysora⁠⁠ 

Twitter- ⁠⁠x.com/nysora⁠⁠ 

TikTok- ⁠⁠tiktok.com/@nysora_inc⁠⁠ 

--------------------------------------------------------- ⁠⁠

#nysora⁠⁠ ⁠⁠#regionalanesthesia⁠⁠ ⁠⁠#anesthesia⁠⁠

Disclaimer: Medicine is an ever-changing science. As new research and clinical experience broaden, changes in treatment and drug therapy are required. The authors and publishers have checked with sources believed to be reliable in efforts to provide accurate information within the available or accepted standards of care. However, given the possibility of human error or changes in medical practice, neither the authors nor the publisher, nor any other party involved in the preparation of this platform warrants that the information contained herein is in every aspect accurate or complete, and they disclaim all responsibility for any errors or omissions for the results obtained from the use of the information contained in this work. Readers are advised to confirm the information contained herein with other sources. For example, readers are advised to check the product information of each drug mentioned, and that any information contained on NYSORA's Podcast is accurate.

In this episode of Updates in Anesthesiology, Dr. Hadzic reviews the newly published 2025 international clinical practice guidelines on platelet transfusion, co-led by Dr. Ryan Metcalf from the University of Utah and Dr. Simon Stanworth from Oxford, and published in JAMA. Based on evidence from over 30 studies, these guidelines recommend restrictive platelet transfusion thresholds in both adult and pediatric populations, advocating for transfusions only when platelet counts are critically low in specific scenarios. The goal? Minimize unnecessary transfusions, reduce patient harm, and conserve resources without increasing bleeding or mortality.

Where else to find us:
Web- ⁠⁠http://www.nysora.com⁠⁠ 

Instagram- ⁠⁠instagram.com/nysora.inc/ ⁠⁠

LinkedIN- ⁠⁠linkedin.com/company/nysora-inc/⁠⁠ 

Facebook- ⁠⁠facebook.com/nysora⁠⁠ 

Twitter- ⁠⁠x.com/nysora⁠⁠ 

TikTok- ⁠⁠tiktok.com/@nysora_inc⁠⁠ 

--------------------------------------------------------- ⁠⁠

#nysora⁠⁠ ⁠⁠#regionalanesthesia⁠⁠ ⁠⁠#anesthesia⁠⁠

Disclaimer: Medicine is an ever-changing science. As new research and clinical experience broaden, changes in treatment and drug therapy are required. The authors and publishers have checked with sources believed to be reliable in efforts to provide accurate information within the available or accepted standards of care. However, given the possibility of human error or changes in medical practice, neither the authors nor the publisher, nor any other party involved in the preparation of this platform warrants that the information contained herein is in every aspect accurate or complete, and they disclaim all responsibility for any errors or omissions for the results obtained from the use of the information contained in this work. Readers are advised to confirm the information contained herein with other sources. For example, readers are advised to check the product information of each drug mentioned, and that any information contained on NYSORA's Podcast is accurate.

In this episode of Updates in Anesthesiology, Dr. Hadzic breaks down the results from the PRECISION study published in Anesthesiology (2025). Led by Dr. Cui and colleagues, this prospective trial reveals that nearly 1 in 9 older patients undergoing noncardiac surgery, especially neurosurgical, experience covert strokes detectable only by MRI. These “silent” strokes double the risk of postoperative delirium and long-term cognitive decline. Tune in to hear what this means for perioperative care, how to identify patients at risk, and actionable strategies to protect brain health after surgery.

Where else to find us:
Web- ⁠⁠http://www.nysora.com⁠⁠ 

Instagram- ⁠⁠instagram.com/nysora.inc/ ⁠⁠

LinkedIN- ⁠⁠linkedin.com/company/nysora-inc/⁠⁠ 

Facebook- ⁠⁠facebook.com/nysora⁠⁠ 

Twitter- ⁠⁠x.com/nysora⁠⁠ 

TikTok- ⁠⁠tiktok.com/@nysora_inc⁠⁠ 

--------------------------------------------------------- ⁠⁠

#nysora⁠⁠ ⁠⁠#regionalanesthesia⁠⁠ ⁠⁠#anesthesia⁠⁠

Disclaimer: Medicine is an ever-changing science. As new research and clinical experience broaden, changes in treatment and drug therapy are required. The authors and publishers have checked with sources believed to be reliable in efforts to provide accurate information within the available or accepted standards of care. However, given the possibility of human error or changes in medical practice, neither the authors nor the publisher, nor any other party involved in the preparation of this platform warrants that the information contained herein is in every aspect accurate or complete, and they disclaim all responsibility for any errors or omissions for the results obtained from the use of the information contained in this work. Readers are advised to confirm the information contained herein with other sources. For example, readers are advised to check the product information of each drug mentioned, and that any information contained on NYSORA's Podcast is accurate.

In this episode of Updates in Anesthesiology, Dr. Hadzic breaks down the largest real-world study to date comparing the environmental impact of general anesthesia strategies. With over 35,000 cases analyzed, discover why TIVA with propofol has emerged as the lowest carbon emitter, outperforming even optimized sevoflurane techniques. We’ll explore the GHG numbers, plastic waste concerns, and clinical outcomes, and conclude with practical tips to make your OR practice more sustainable without compromising patient care.

Where else to find us:
Web- ⁠⁠http://www.nysora.com⁠⁠ 

Instagram- ⁠⁠instagram.com/nysora.inc/ ⁠⁠

LinkedIN- ⁠⁠linkedin.com/company/nysora-inc/⁠⁠ 

Facebook- ⁠⁠facebook.com/nysora⁠⁠ 

Twitter- ⁠⁠x.com/nysora⁠⁠ 

TikTok- ⁠⁠tiktok.com/@nysora_inc⁠⁠ 

--------------------------------------------------------- ⁠⁠

#nysora⁠⁠ ⁠⁠#regionalanesthesia⁠⁠ ⁠⁠#anesthesia⁠⁠

Disclaimer: Medicine is an ever-changing science. As new research and clinical experience broaden, changes in treatment and drug therapy are required. The authors and publishers have checked with sources believed to be reliable in efforts to provide accurate information within the available or accepted standards of care. However, given the possibility of human error or changes in medical practice, neither the authors nor the publisher, nor any other party involved in the preparation of this platform warrants that the information contained herein is in every aspect accurate or complete, and they disclaim all responsibility for any errors or omissions for the results obtained from the use of the information contained in this work. Readers are advised to confirm the information contained herein with other sources. For example, readers are advised to check the product information of each drug mentioned, and that any information contained on NYSORA's Podcast is accurate.

In this episode of UPDATES IN ANESTHESIOLOGY, Dr. Hadzic discusses a new international consensus on apnoeic oxygenation using high-flow nasal oxygen (HFNO) during laryngotracheal surgery. Featuring insights from a newly published 19-item safety checklist in the European Journal of Anaesthesiology, we break down what every clinician needs to know, from patient selection to post-op care, to improve safety and streamline multidisciplinary workflows. Whether you're already using THRIVE or just curious about best practices, this episode gives you the practical takeaways to elevate your airway game.

Where else to find us:
Web- ⁠⁠http://www.nysora.com⁠⁠ 

Instagram- ⁠⁠instagram.com/nysora.inc/ ⁠⁠

LinkedIN- ⁠⁠linkedin.com/company/nysora-inc/⁠⁠ 

Facebook- ⁠⁠facebook.com/nysora⁠⁠ 

Twitter- ⁠⁠x.com/nysora⁠⁠ 

TikTok- ⁠⁠tiktok.com/@nysora_inc⁠⁠ 

--------------------------------------------------------- ⁠⁠

#nysora⁠⁠ ⁠⁠#regionalanesthesia⁠⁠ ⁠⁠#anesthesia⁠⁠

Disclaimer: Medicine is an ever-changing science. As new research and clinical experience broaden, changes in treatment and drug therapy are required. The authors and publishers have checked with sources believed to be reliable in efforts to provide accurate information within the available or accepted standards of care. However, given the possibility of human error or changes in medical practice, neither the authors nor the publisher, nor any other party involved in the preparation of this platform warrants that the information contained herein is in every aspect accurate or complete, and they disclaim all responsibility for any errors or omissions for the results obtained from the use of the information contained in this work. Readers are advised to confirm the information contained herein with other sources. For example, readers are advised to check the product information of each drug mentioned, and that any information contained on NYSORA's Podcast is accurate.

 In this episode of Updates in Anesthesiology, Dr. Hadzic unpacks the FRAIL-HIP study published in JAMA Surgery, which challenges the routine use of surgery for proximal femoral fractures in frail, institutionalized older adults. You'll hear how nonoperative management, guided by a structured shared decision-making process, can lead to comparable quality of life, fewer adverse events, and even a more dignified dying experience. Tune in to discover how this paradigm shift could reshape your approach to surgical decisions in end-of-life care.

Where else to find us:
Web- ⁠⁠http://www.nysora.com⁠⁠ 

Instagram- ⁠⁠instagram.com/nysora.inc/ ⁠⁠

LinkedIN- ⁠⁠linkedin.com/company/nysora-inc/⁠⁠ 

Facebook- ⁠⁠facebook.com/nysora⁠⁠ 

Twitter- ⁠⁠x.com/nysora⁠⁠ 

TikTok- ⁠⁠tiktok.com/@nysora_inc⁠⁠ 

--------------------------------------------------------- ⁠⁠

#nysora⁠⁠ ⁠⁠#regionalanesthesia⁠⁠ ⁠⁠#anesthesia⁠⁠

Disclaimer: Medicine is an ever-changing science. As new research and clinical experience broaden, changes in treatment and drug therapy are required. The authors and publishers have checked with sources believed to be reliable in efforts to provide accurate information within the available or accepted standards of care. However, given the possibility of human error or changes in medical practice, neither the authors nor the publisher, nor any other party involved in the preparation of this platform warrants that the information contained herein is in every aspect accurate or complete, and they disclaim all responsibility for any errors or omissions for the results obtained from the use of the information contained in this work. Readers are advised to confirm the information contained herein with other sources. For example, readers are advised to check the product information of each drug mentioned, and that any information contained on NYSORA's Podcast is accurate.

In this episode of Updates in Anesthesiology, Dr. Hadzic breaks down the latest evidence comparing ketamine, etomidate, and propofol for tracheal intubation in critically ill patients. Drawing from a 2025 review in Critical Care Medicine, we explore why ketamine is emerging as the safest and most reliable option, while etomidate shows a potential mortality risk, and propofol continues to raise red flags for cardiovascular instability. Get the evidence, the implications, and the practical takeaways, all in one focused episode.

Where else to find us:
Web- ⁠⁠http://www.nysora.com⁠⁠ 

Instagram- ⁠⁠instagram.com/nysora.inc/ ⁠⁠

LinkedIN- ⁠⁠linkedin.com/company/nysora-inc/⁠⁠ 

Facebook- ⁠⁠facebook.com/nysora⁠⁠ 

Twitter- ⁠⁠x.com/nysora⁠⁠ 

TikTok- ⁠⁠tiktok.com/@nysora_inc⁠⁠ 

--------------------------------------------------------- ⁠⁠

#nysora⁠⁠ ⁠⁠#regionalanesthesia⁠⁠ ⁠⁠#anesthesia⁠⁠

Disclaimer: Medicine is an ever-changing science. As new research and clinical experience broaden, changes in treatment and drug therapy are required. The authors and publishers have checked with sources believed to be reliable in efforts to provide accurate information within the available or accepted standards of care. However, given the possibility of human error or changes in medical practice, neither the authors nor the publisher, nor any other party involved in the preparation of this platform warrants that the information contained herein is in every aspect accurate or complete, and they disclaim all responsibility for any errors or omissions for the results obtained from the use of the information contained in this work. Readers are advised to confirm the information contained herein with other sources. For example, readers are advised to check the product information of each drug mentioned, and that any information contained on NYSORA's Podcast is accurate.