Moderator: James P. Rathmell, M.D. Participants: Nikolay O. Kamenshchikov, M.D. and Lorenzo Berra, M.D. and Kamrouz Ghadimi, M.D.

Articles Discussed: Perioperative Nitric Oxide Conditioning Reduces Acute Kidney Injury in Cardiac Surgery Patients with Chronic Kidney Disease (the DEFENDER Trial): A Randomized Controlled Trial Nitric Oxide and Kidney Injury after Cardiac Surgery: A Solution Looking for a Problem

Moderator: James P. Rathmell, M.D. Participants: Paul Lee-Archer and Clyde Matava, M.B.Ch.B., M.Med., M.H.S.C.

Articles Discussed: Development of the Pediatric Scale for Quality of Recovery (PedSQoR) Measuring what Matters - the Pediatric Scale for Quality of Recovery

Creator: James P. Rathmell, M.D.

August 2025, Volume 143, Issue 2

Overview of August issue original studies.

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Moderator: James P. Rathmell, M.D. Participants: Albert Garcia-Casanovas, M.H.A. and Douglas Colquhoun, M.B., M.Sc., M.P.H. Articles Discussed: Association Between Adherence to Patient Blood Management Recommendations and Postoperative Complications in Hip and Knee Arthroplasty Patient Blood Management: Moving Beyond Guidelines to Action

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Moderator: BobbieJean Sweitzer, M.D. Participants: Jessica R Ansari, M.D., M.S. and Craig M. Palmer, M.D. Articles Discussed: Uterine Tone Numeric Rating Score as an Early Indicator of Major Postpartum Hemorrhage During Cesarean Delivery: A Prospective Observational Study Predicting the Unpredictable: A New Approach to Predict Postpartum Hemorrhage from Uterine Atony Transcript

Creator: James P. Rathmell, M.D.

July 2025, Volume 143, Issue 1

Overview of July issue original studies.

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Moderator: James P. Rathmell, M.D. Participants: Carmen Bozic, M.D. Articles Discussed: Suzetrigine, a Nonopioid NaV1.8 Inhibitor for Treatment of Moderate-to-severe Acute Pain: Two Phase 3 Randomized Clinical Trials Suzetrigine: First in a New Class of Nonopioid Analgesics for Acute Pain

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Moderator: James P. Rathmell, M.D. Participants: Rebecca L. Wu, M.D. and Max B. Kelz, M.D., Ph.D. Articles Discussed: TAK-925 (danavorexton), an Orexin Receptor 2 Agonist, Reduces Opioid-Induced Respiratory Depression and Sedation Without Affecting Analgesia in Healthy Adult Males Alluring Potential to Accelerate Emergence and Ameliorate Opioid-induced Respiratory Depression without Antagonizing Analgesia: Danavorexton Enters the Anesthetic Landscape Transcript

Moderator: BobbieJean, M.D. Participants: Douglas Colquhoun, M.B., M.Sc., M.P.H. and Stephan R. Thilen Articles Discussed: Neuromuscular Blockade and Antagonism in Patients with Renal Impairment: A Multicenter Retrospective Cross Sectional Study On and Off Label Use of Sugammadex in Patients with Renal Impairment in the 6 ½ Years Following FDA Approval Transcript

Creator: James P. Rathmell, M.D., M.B.A.

June 2025, Volume 142, Issue 6

Overview of June issue original studies.

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