AUA2026: Focus on: ADT in the Modern Era - Balancing Cancer Control and Cardiovascular Safety

CME Available: https://cme.auanet.org/URL/FOCUS265ONL

LEARNING OBJECTIVES:

After participating in this CME activity, participants will be able to:

1. Integrate cardiovascular (CV) risk assessment into ADT initiation by applying key findings from the REVELUTION-1 trial to identify patients at elevated risk for atherosclerosis and MACE.

2. Compare and apply the CV safety profiles of LHRH agonists versus GnRH receptor antagonists to guide personalized ADT selection in patients with varying CV risk.

3. Implement streamlined monitoring strategies for men on oral ADT, including testosterone levels, lipid and blood pressure evaluation, and surveillance for early CV risk indicators.

4. Collaborate with cardiology and primary care to optimize statin use and coordinate CV risk-reduction strategies for prostate cancer patients receiving ADT.

5. Strengthen shared decision making and adherence by incorporating discussions of oncologic benefit, CV risk, and mitigation strategies into routine oral ADT counseling and follow-up.

ACKNOWLEDGEMENTS:

Support provided by independent educational grants from:

Pfizer, Inc

Sumitomo Pharma America, Inc.