USC faces trouble on the road as the Oregon Ducks eye playoff glory–can Jayden Maiava spark a Trojans upset, or will Dante Moore and Oregon’s powerhouse ground game prove too much? Rivalry week looms as Ohio State, still managing injuries to Carnell Tate and Jeremiah Smith, look to stay sharp against Rutgers, and Michigan juggles running back depth issues ahead of their highly anticipated showdown with the Buckeyes.

Craig Shemon breaks down every Big Ten matchup and bold, offers fearless “Pigskin Picks,” including why the OVER could be the smart play in Michigan vs. Maryland, and whether Northwestern can clinch bowl eligibility against Minnesota. Get insights on Wisconsin’s quarterback carousel, Penn State’s disastrous season turnaround, and surprise bowl bids on the horizon. Locked On Big Ten covers bold predictions, critical injury news, and playoff scenarios you can’t afford to miss.

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