In this episode of Weight Loss Simplified, Jennifer Powter sits down with Marcelle Pick, OB/GYN, NP, to expose the hidden connection between stress, adrenal dysfunction, and weight gain.

If you’re exhausted, struggling to lose weight despite doing “everything right,” or constantly overwhelmed, your adrenals may be the missing link. Marcelle unpacks how chronic stress disrupts hormones, metabolism, and overall health—while Western medicine largely ignores the problem.

Discover why traditional weight loss advice fails women with adrenal dysfunction, how stress fuels weight gain, and the exact steps you can take to restore balance.

In this episode:

00:00 - Introduction: Why adrenal health is critical for women over 40

01:22 - Meet Marcelle Pick: Her 40+ years of clinical experience in women’s health

03:50 - What are the adrenal glands, and why do they matter?

05:21 - The stress response: How your body reacts to modern-day pressure

07:02 - The real impact of chronic stress on hormones, metabolism, and energy

08:50 - Why most women are misdiagnosed with thyroid issues instead of adrenal dysfunction

10:49 - Signs your adrenals are struggling: Fatigue, stubborn weight, brain fog, and more

12:26 - The link between perimenopause, menopause, and adrenal health

14:00 - Breaking the cycle: Practical strategies to restore adrenal function

16:33 - How diet, sleep, and lifestyle choices impact stress and cortisol

17:06 - The danger of fasting for women with adrenal dysfunction

19:42 - How unresolved trauma affects stress levels and weight loss resistance

22:32 - Why women need strong social support for long-term health

23:39 - Reconnecting with intuition: Why self-care isn’t selfish

25:30 - The wake-up call: How to listen to your body before it breaks down

27:11 - Why traditional medicine treats symptoms, not root causes

29:26 - First steps to take if you suspect adrenal dysfunction

30:18 - Free adrenal support guide: How to assess and start healing

Episode Resources:

• Get Marcelle Pick’s Free Adrenal Support Guide – Download it here
• Follow Marcelle Pick for More Expert Advice:

YouTube

Instagram

Facebook

Website

• Learn more about the Powter Method for Permanent Weight Loss here
• Read Jennifer's books for free - "Diet Disruption" and "Stop Sabotaging Your Weight Loss"
• Book a FREE Weight Loss Breakthrough Call here. 
• Join my free Diet Disruption Facebook Community here.
• Got a burning question about weight loss, mindset, emotional eating or breaking free from the dieting cycle? I’d love to hear it! You can Ask Me Anything here

Subscribe and Review:

Loved today's episode? Share it with a friend and subscribe to "Weight Loss Simplified" on your favorite podcast platform. 

Leave us a five-star rating and a review on iTunes; your feedback helps us grow and reach more people on their weight loss journey.