Talking With Docs Podcast

Can Creatine Reduce Depression?


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Is Creatine Just for Muscles? New Study Says No

Creatine is known for building strength — but new research shows it may also reduce symptoms of depression.

In this episode, doctors break down a study where creatine, combined with CBT (cognitive-behavioural therapy), helped improve mental health. It’s safe, accessible, and now showing promise beyond physical performance.

We cover:

  • How creatine affects brain function
  • What a recent clinical trial revealed
  • Whether creatine could support mood and therapy
  • Who might benefit and if it's safe to try

If you take creatine or are curious about mental health supplements, this is for you.

👍 Like if you learned something 💬 Comment with your questions 🔔 Subscribe for more doctor-led breakdowns

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📄 Study Reference: Sherpa NN, et al. Creatine + CBT in depression. Eur Neuropsychopharmacol. 2025;90:28–35. https://doi.org/10.1016/j.euroneuro.2024.10.004

🛑 DISCLAIMER: This content is for informational purposes only. It is not medical advice. Always consult your healthcare provider. For emergencies, call 911. Full terms at talkingwithdocs.com

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Talking With Docs PodcastBy Dr. Brad Weening and Dr. Paul Zalzal

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