Described as her best big screen role in decades, Demi Moore talks about her debut in Cannes’ Official Selection as the co-star of “The Substance”. In this body horror picture with a feminist take, Moore stars alongside Margaret Qualley and Dennis Quaid. Moore plays a fading Hollywood star whose career is set to be axed by misogynists when she’s offered a secret new medical procedure. The movie is directed by French filmmaker Coralie Fargeat and had audience laughing, wincing and gasping in disbelief.