CFPCLearn

otre patience est maintenant récompensée, voici notre tant attendue série goutteuse! Dans ce 60ème épisode du Pharmascope, Nicolas, Sébastien et Isabelle discutent épidémiologie, facteurs de risque, manifestations cliniques et prise en charge des crises de goutte.

Les objectifs pour cet épisode sont:

• Identifier les facteurs de risque de goutte
• Expliquer les manifestations aiguës et chroniques de la goutte
• Expliquer les bénéfices et les risques associés aux traitements utilisés en crise de goutte

Ressources pertinentes en lien avec l'épisode

Lignes directrices portant sur la prise en charge de la goutte FitzGerald JD et coll. 2020 American College of Rheumatology Guideline for the Management of Gout. Arthritis Rheumatol. 2020;72:879-95.

Richette P et coll. 2018 updated European League Against Rheumatism evidence-based recommendations for the diagnosis of gout. Ann Rheum Dis. 2020;79:31-8.

Qaseem A et coll. Management of Acute and Recurrent Gout: A Clinical Practice Guideline From the American College of Physicians. Ann Intern Med. 2017;166:58-68.

Articles de revue portant sur la prise en charge de la goutte Drug and Therapeutics Bulletin. Latest guidance on the management of gout. BMJ. 2018;362:k2893.

Sidari A, Hill E. Diagnosis and Treatment of Gout and Pseudogout for Everyday Practice. Prim Care. 2018;45:213-36.

Dugré N. L'hyperuricémie et la goutte. Québec Pharmacie. Juin/juillet 2015. 25p.

Études portant sur le traitement aigu de la goutte van Durme CMPG et coll. Non-steroidal anti-inflammatory drugs for acute gout. Cochrane Database Syst Rev. 2014;9:CD010120.

Terkeltaub RA et coll. High versus low dosing of oral colchicine for early acute gout flare: Twenty-four-hour outcome of the first multicenter, randomized, double-blind, placebo-controlled, parallel-group, dose-comparison colchicine study. Arthritis Rheum. 201062:1060-8.

Roddy E et coll. Open-label randomised pragmatic trial (CONTACT) comparing naproxen and low-dose colchicine for the treatment of gout flares in primary care. Ann Rheum Dis. 2020;79:276-84.

In episode 608, Tina and James invite Jennifer Young back again to the podcast to go over the evidence we have for a simple but important question around buckle fractures – does treating with a soft bandage versus a rigid splint/cast produce different clinical outcomes? The answer is quite clear around what we should do. Check out what we found.

Show Notes 1) Tools For Practice Use the soft touch for buckle fractures?

2) PEIP Conference Edmonton October 17-18, 2025

In episode 607, Tina and James invite Caitlin Finley to go over what the group found with regard to the best available evidence around surgical frenotomy. We look at the effect the surgery has on breast pain, self-reported breastfeeding improvement, and infant weight gain. Tune in as you might be impressed with the absolute benefits.

Show Notes 1) Tools For Practice Trying Tongue-Tie Treatment: Does Frenotomy Fix Feeding Frustrations?

2) PEIP Conference Edmonton October 17-18, 2025

Al Dosterone, a 54 year old man presenting with difficult to control blood pressure

Olive Peloponnese, a 50 year old woman with coming in to review her "bad cholesterol."

Per Colate, Part II, a 72 year old man presenting with ongoing symptoms of nocturia and urinary frequency

Rusty Malassez, a 62 year old presenting with rash on face and chest.

In episode 606, Jamie and James go over the best available evidence we have for the medications used in overactive bladder, with a focus on a newer agent mirabegron. We end up having to discuss the exciting topics of number of voids and dry mouth and at the end we give you all the numbers you need to have an evidence-based conversation with your patients.

Show Notes 1) Tools For Practice Avoiding the void? Mirabegron for overactive bladder

2) PEIP Conference Edmonton October 17-18, 2025

In episode 605, James and Jamie get Emelie Braschi to answer a simple and common clinical question. ASA versus direct oral anticoagulants – which one is safer with regard to bleeding? As always it comes down to the numbers and we go over all those numbers and put them into the overall benefit and harm ratio for Afib.

Show Notes 1) Tools For Practice An ASA a day keeps the Afib at bay?

2) SparcTool – Stroke Prevention in Atrial Fibrillation Risk Tool

3) PEIP Conference Edmonton October 17-18, 2025

In episode 604, James and Mike K get Jennifer Young to tackle the topic of nose bleeds and what the evidence shows around the use of topical tranexamic acid and how it compares to other treatments. We go over all the endpoints and give you all the numbers.

Show Notes 1) Tools For Practice Stop the Drip: Tranexamic Acid Solution for Nosebleeds

2) PEIP Conference Edmonton October 17-18, 2025