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In episode 603, James and Mike K invite Jennifer Young back to the podcast to talk about the best available evidence for topical minoxidil and hair growth. We discuss outcomes such as the numbers of hairs per squared centimeter – the main outcome reported – but when available, we also other report on other outcomes and also the side effects. So, if you want to know about numbers of hair per squared centimeter and all the other numbers, tune in.
Show Notes 1) Tools For Practice Topical minoxidil for androgenetic alopecia: When blood pressure agents make you hairy 2) PEIP Conference Edmonton October 17-18, 2025
Vous êtes toujours parmi nous? La fin approche! Dans ce 47ème épisode du Pharmascope et dernier de la série sur le TDAH, Nicolas, Isabelle et leur invitée discutent entre autres des options de traitement pharmacologiques autres que les psychostimulants.
Les objectifs pour cet épisode sont :
Ressources pertinentes en lien avec l'épisode
Lignes directrices canadiennes CADDRA – Canadian ADHD Ressource Alliance : Lignes directrices canadiennes pour le TDAH, quatrième édition, Toronto (Ontario); CADDRA 2018.
Lignes directrices américaines Wolraich ML et coll. Clinical Practice Guideline for the Diagnosis, Evaluation, and Treatment of Attention-Deficit/Hyperactivity Disorder in Children and Adolescents. Subcommittee on children and adolescents with attention-deficit / hyperactive disorder. Pediatrics 2019. 144(4). pii:e20192528.
Revues du TDAH Thapar A, Cooper M. Attention deficit hyperactivity disorder. Lancet. 2016;387(10024):1240-50.
Auclair M, Elalami M. Traitement du TDAH chez l'enfant. Québec Pharmacie. Septembre 2018. 28p.
Revue systématique globale Stuhec M, Lukic P, Locatelli I. Efficacy, Acceptability, and Tolerability of Lisdexamfetamine, Mixed Amphetamine Salts, Methylphenidate, and Modafinil in the Treatment of Attention-Deficit Hyperactivity Disorder in Adults: A Systematic Review and Meta-analysis. Ann Pharmacother. 2019; 2:121-133.
Liens utiles pour ressources Canadian ADHD Ressource Alliance (CADDRA). 2020.
Centre for ADHD awareness, Canada (CADDAC). 2017.
Clinique FOCUS. 2020.
Annick Vincent. TDAH, informations, trucs et astuces. 2020.
Méta-analyse comparant l'atomoxétine aux psychostimulants en TDAH Liu Q, Zhang H, Fang Q, et coll. Comparative Efficacy and Safety of Methylphenidate and Atomoxetine for Attention-Deficit Hyperactivity Disorder in Children and Adolescents: Meta-analysis Based on Head-To-Head Trials. J Clin Exp Neuropsychol. 2017; 39(9): 854-65.
Évaluation de la guanfacine en TDAH par l'INESSS Institut national d'excellence en santé et services sociaux. INTUNIV XRMC – Trouble du déficit de l'attention avec ou sans hyperactivité. Février 2014.
Étude portant sur des doses de 1 à 7mg de guanfacine en TDAH chez l'adolescent Wilens TE, Robertson B, Sikirica V, et coll. A Randomized, Placebo-Controlled Trial of Guanfacine Extended Release in Adolescents With Attention-Deficit/Hyperactivity Disorder. J Am Acad Child Adolesc Psychiatry 2015;54(11):916–925.
Restez concentrés parce que ce n'est pas terminé! Après un premier épisode sur le diagnostic et la prise en charge non-pharmacologique du TDAH, on porte cette fois toute notre attention sur les pilules. Dans ce 46ème épisode du Pharmascope, Nicolas, Isabelle et leur invitée discutent donc du traitement pharmacologique du TDAH, plus spécifiquement des psychostimulants.
Les objectifs pour cet épisode sont :
Ressources pertinentes en lien avec l'épisode
Lignes directrices canadiennes CADDRA – Canadian ADHD Ressource Alliance : Lignes directrices canadiennes pour le TDAH, quatrième édition, Toronto (Ontario); CADDRA 2018.
Lignes directrices américaines Wolraich ML et coll. Clinical Practice Guideline for the Diagnosis, Evaluation, and Treatment of Attention-Deficit/Hyperactivity Disorder in Children and Adolescents. Subcommittee on children and adolescents with attention-deficit / hyperactive disorder. Pediatrics 2019. 144(4). pii:e20192528.
Revues du TDAH Thapar A, Cooper M. Attention deficit hyperactivity disorder. Lancet. 2016;387(10024):1240-50.
Auclair M, Elalami M. Traitement du TDAH chez l'enfant. Québec Pharmacie. Septembre 2018. 28p.
Revues systématiques portant sur les mesures non-pharmacologiques Good AP et coll. Nonpharmacologic Treatments for Attention-Deficit / Hyperactivity Disorder: A Systematic Review. Pediatrics. 2018;141(6). Pii:e20180094.
Lopez PL et coll. Cognitive-behavioural interventions for attention deficit hyperactivity disorder (ADHD) in adults. Cochrane Database Syst Rev. 2018,23(3):CD010840.
Études portant sur l'effet des amphétamines Punja S et coll. Amphetamines for attention deficit hyperactivity disorder (ADHD) in children and adolescents. Cochrane Database Syst Rev.2016;2:CD009996.
Castells X et coll. Amphetamines for attention deficit hyperactivity disorder (ADHD) in adults. Cochrane Database Syst Rev.2018;8:CD007813.
Études portant sur l'effet du méthylphénidate Storebo OJ et coll. Methylphenidate for children and adolescents with attention deficit hyperactivity disorder (ADHD). Cochrane Database Syst Rev. 2015;11:CD009885.
Epstein T et coll. Immediate-release methylphenidate for attention deficit hyperactivity disorder (ADHD) in adults. Cochrane Database Syst Rev. 2014;9:CD005041.
MTA Cooperative Group. A 14-month randomized clinical trial of treatment strategies for attention-deficit/hyperactivity disorder. Multimodal Treatment Study of Children with ADHD. Arch Gen Psychiatry. 1999;56:1073-86.
Revue systématique globale Stuhec M, Lukic P, Locatelli I. Efficacy, Acceptability, and Tolerability of Lisdexamfetamine, Mixed Amphetamine Salts, Methylphenidate, and Modafinil in the Treatment of Attention-Deficit Hyperactivity Disorder in Adults: A Systematic Review and Meta-analysis. Ann Pharmacother. 2019; 2:121-133.
Liens utiles pour ressources Canadian ADHD Ressource Alliance (CADDRA). 2020.
Centre for ADHD awareness, Canada (CADDAC). 2017.
Clinique FOCUS. 2020.
Annick Vincent. TDAH, informations, trucs et astuces. 2020.
Attention, attention! Un nouvel épisode du Pharmascope est maintenant disponible! Et, cette fois, il va falloir rester concentré parce qu'on a fait trois épisodes sur le TDAH . Dans ce 45ème épisode du Pharmascope et premier de cette série, Nicolas, Isabelle et leur invitée de marque discutent des manifestations cliniques, de l'approche diagnostique et de la prise en charge initiale du TDAH.
Les objectifs pour cet épisode sont:
Ressources pertinentes en lien avec l'épisode
Lignes directrices canadiennes CADDRA – Canadian ADHD Ressource Alliance : Lignes directrices canadiennes pour le TDAH, quatrième édition, Toronto (Ontario); CADDRA 2018.
Lignes directrices américaines Wolraich ML et coll. Clinical Practice Guideline for the Diagnosis, Evaluation, and Treatment of Attention-Deficit/Hyperactivity Disorder in Children and Adolescents. Subcommittee on children and adolescents with attention-deficit / hyperactive disorder. Pediatrics 2019. 144(4). pii:e20192528.
Revues du TDAH Thapar A, Cooper M. Attention deficit hyperactivity disorder. Lancet. 2016;387(10024):1240-50.
Auclair M, Elalami M. Traitement du TDAH chez l'enfant. Québec Pharmacie. Septembre 2018. 28p.
Revues systématiques portant sur les mesures non-pharmacologiques Good AP et coll. Nonpharmacologic Treatments for Attention-Deficit / Hyperactivity Disorder: A Systematic Review. Pediatrics. 2018;141(6). Pii:e20180094.
Lopez PL et coll. Cognitive-behavioural interventions for attention deficit hyperactivity disorder (ADHD) in adults. Cochrane Database Syst Rev. 2018,23(3):CD010840.
Gillies D et coll. Polyunsaturated fatty acids (PUFA) for attention deficit hyperactivity disorder (ADHD) in children and adolescents. Cochrane Database Syst Rev. 2012.(7):CD007986.
Liens utiles pour ressources Canadian ADHD Ressource Alliance (CADDRA). 2020.
Centre for ADHD awareness, Canada (CADDAC). 2017.
Clinique FOCUS. 2020.
Annick Vincent. TDAH, informations, trucs et astuces. 2020.
In episode 602, James and Mike Kolber go over the best available evidence for the benefits and the harms for one of the most commonly used classes of medications – proton pump inhibitors. We find out the benefit numbers are much larger than the harm numbers. Check out the podcast to get all the numbers you need to help people make decisions.
Show Notes 1) Tools For Practice Side effects of long-term PPI use: Leaving a bad taste in your mouth? Proton Pump Inhibitors (PPIs): Is Perpetual Prescribing Inevitable?
2) PEIP Conference Edmonton October 17-18, 2025
3) SPARCTool
4) RX files PPI Stopping your Proton Pump Inhibitor or "PPI"
In episode 601, James and Mike invite Jennifer Young back to the podcast to go over all the evidence we have for pregabalin and gabapentin in patients with fibromyalgia. During the discussion we find out how many people actually get a ≥30% reduction in pain compared to placebo. We even look at some information about different doses. All the numbers are revealed by the end of the podcast – and we give tips and suggestions throughout. Check it out.
Show Notes 1) Tools For Practice Pharm for Fibro, Round 2: Can gabapentinoids ease the pain?
2) MEME Conference 2025 in Vancouver – May 9/10, 2025
In this episode of In the Clinic, Mike and Jess invite back Dr. Jennifer Young. The team discusses Benazir Pervez, a 17-year-old female coming in for acne.
In this episode of In the Clinic, Mike and Jess invite back Dr. Émélie Braschi. The team discusses Micti Colate, a 70-year-old female coming in for urinary incontinence.
In this episode of In the Clinic, Mike and Jess invite back Dr. Jennifer Young. The team discusses Annie Ploidy, a 36-year-old female coming in for prenatal screening.
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