Chasing Life with Dr. Sanjay Gupta

There's no shortage of products and procedures promising a quick way to weight loss. But do they work? Or is it all just marketing and hype? In this episode, Sanjay speaks with Dr. Mikhail Varshavski – better known as Doctor Mike — who has made it his mission to debunk medical misinformation. He’ll dive into popular weight loss methods, how they supposedly work, and the truth behind cleanses, juices, tummy teas, and more.

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Thirteen years ago, Seattle-based writer Lindy West wrote an essay that took the internet by storm called “Hello, I’m Fat.” That essay would become the 2016 New York Times best-selling memoir, Shrill: Notes from a Loud Woman, and later a Hulu television series. On today’s episode, Lindy, who is still writing and hosts a podcast, sits down with CNN’s Chief Medical correspondent Dr. Sanjay Gupta for a candid and honest conversation about living as a self-described “fat” person, and how the way she thinks about weight has changed since writing Shrill. 

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How much do our genetics determine our destiny when it comes to how much we weigh? Cambridge geneticist Giles Yeo says your genes play a bigger role than you might think. “In casino terms, the house will always win if the die is weighted just a little bit one way versus the other.” On today’s Chasing Life, Professor Yeo, a pioneer in the field of obesity research, joins Dr. Sanjay Gupta to explain his ground-breaking research into why some people are genetically predisposed to eat more, and why it’s still so controversial to classify obesity as a “disease.” Plus, Professor Yeo shares how to treat and prevent obesity, a condition that impacts more than 40 percent of Americans, and counting.

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Weight gain is a common complaint among women in their 40s and 50s, with many blaming it on the ups and downs of menopause. But what exactly is the connection between menopause and weight gain? And can anything to be done to avoid it? In this episode, Sanjay speaks to Dr. Monica Christmas, the director of the menopause program at the University of Chicago Medicine and an associate professor of obstetrics and gynecology. She explains effective strategies for tackling midlife weight gain and shares practical advice on navigating this transformative phase with grace.

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Alabama’s Supreme Court has ruled that embryos are children and anyone discarding frozen embryos could face wrongful death charges. So where does this leave fertility doctors and their patients in the state? And could this ruling have national implications? For this special episode, Dr. Sanjay Gupta turns to IVF expert, Dr. Eve Feinberg from the Feinberg School of Medicine at Northwestern University. She explains how embryos are handled during the IVF process and why the ruling is contentious for fertility care providers. Also, CNN Correspondent Isabel Rosales shares how some families and fertility clinics in Alabama have responded.

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Children and adolescents are expected to gain weight as they age, but how much is too much? Childhood obesity rates are on the rise, along with disordered eating among teens. So how can kids and their parents address this head on? Dr. Jack Yanovski, a pediatric endocrinologist at the National Institute of Child Health and Human Development recommends first determining who is most concerned about the weight. From there, he tells Sanjay about the causes and consequences of high body weight in kids, as well as treatment options – which include weight loss medications for children as young as 12. Dr. Yanovski also offers guidance on how to talk to kids about food and weight.

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Long before WeightWatchers became a weight loss empire, the legacy dieting company started as a small support group in the 1960s. The company rose to popularity preaching a message of moderation and making healthy choices. But in what some call a surprising pivot, WeightWatchers is changing the way the company does business. On today’s Chasing Life, CEO Sima Sistani sits down with Dr. Sanjay Gupta to share why she’s making these big changes, namely, embracing telehealth and weight loss drugs like Wegovy.

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It’s become a multibillion-dollar business: weight loss drugs. Demand is high, as is the cost. How did medications like Ozempic, Wegovy, Mounjaro and Zepbound become so popular and so profitable? And what kind of impact might they have on the future of food and healthcare? Dr. Sanjay Gupta turns to his CNN colleague Meg Tirrell for answers, and a little context about the business behind these new medications.

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New drugs like Wegovy, Ozempic and Mounjaro are billed as a revolutionary new approach for losing weight. But are these actually miracle drugs? Dr. Sanjay Gupta turns to Yale School of Medicine assistant professor Dr. Jorge Moreno to explain the science behind these medications – from the benefits to the risks to the unknowns. Plus, what anyone who’s interested in taking these drugs should know.

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Everybody knows losing weight is tough. But why? While diet, exercise, and willpower might have something to do with it. The root may lie in how we humans have evolved as a species. Could our bodies be hardwired to resist shedding pounds? In this episode, Sanjay speaks to Daniel Lieberman, a paleoanthropologist and professor of human evolutionary biology at Harvard University. He’ll explain how our bodies evolved to hold onto fat as a strategy for survival. Plus, we'll get tips for exercising and eating right, with our evolutionary needs in mind.

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