The Los Angeles Philharmonic Orchestra faced real challenges, as all U.S. orchestras did: an aging subscriber base, disinterest from younger audiences, and development of a pipeline of donors for the future. Harvard Business School professor Rohit Deshpande discusses his case entitled “The Los Angeles Philharmonic Orchestra: Cultural Entrepreneurship” — how protagonist Deborah Borda positioned the orchestra for continued success, building on healthy financials, a celebrity music director (Gustavo Dudamel), the beautiful Walt Disney Concert Hall, and the development of a youth orchestra.

The Chase Sapphire Reserve credit card was one of the hottest product launches in 2016 enthusiastically received by millennial consumers, a group that had previously eluded JPMorgan Chase and its competitors. Harvard Business School professor Shelle Santana discusses her case, “Chase Sapphire: Creating a Millennial Cult Brand” — how protagonists Pam Codispoti and Eileen Serra shifted their focus to retaining customers attracted by the one-time signup bonus of 100,000 reward points and on acquiring new customers now that the bonus had been reduced.

Ride-hailing service Careem, the “Uber of the Middle East,” experienced expansion so dramatic that it monitored its growth target every 15 minutes. Was this a fabled startup unicorn? But doubling the size of the company every six months took its toll. Harvard Business School professor Shikhar Ghosh discusses his case, “Careem: Raising a Unicorn” — how the founders approached a number of critical organizational and cultural issues to keep its 4 million customers satisfied.

Riccardo Zacconi was the co-founder and CEO of King Digital Entertainment, the video game company that had quickly established itself as the world’s leading maker of casual games for mobile devices after the sensational success of its game “Candy Crush Saga.” He’s faced with the central question of whether and how to scale the company through an astronomical period of growth. Harvard Business School professor Jeffrey Rayport discusses his case “King Digital Entertainment” — whether a single creative studio can scale to manage a portfolio of almost 200 games, when one of them is the mammoth hit Candy Crush.

JPMorgan Chase is working with local economic- and workforce-development organizations, small businesses, philanthropies, and the mayor. The goal? To put in place a series of investments to help turn around the struggling city. Harvard Business School professor Joseph Bower and JPMorgan’s head of corporate responsibility, Peter Scher, discuss why businesses should create philanthropic programs of their own. Bower is the author of the case study, “JPMorgan Chase: Invested in Detroit.”

Enel, Italy’s state-owned power company, was one of Europe’s largest coal users and polluters. Now it is recognized as a leader in renewable energy services. How did it engineer that monumental change? Harvard Business School professor Mark Kramer discusses his case, “Enel: The Future of Energy,” — how CEO Francesco Starace’s vision of sustainability drove innovation and fostered a completely new enterprise around developing and promoting renewable energy.

In the 2016 United States presidential election, candidates from both major political parties used anti-establishment messaging to appeal to Americans, a theme that had been on the sidelines of U.S. political discourse for decades. Donald Trump, in particular, played into the rising anti-establishment sentiment, embracing a populist platform and emphasizing his position as a Washington outsider. Why did his message resonate with voters? Harvard Business School professor Rafael Di Tella discusses his case entitled “Populism in America: Fake News, Alternative Facts and Elite Betrayal in the Trump Era” — how many Americans felt betrayed by the educated “elite” view on globalization, and looked to Trump as a president who would put American workers and values first.

Dr. Brian Alexander at the Dana-Farber Cancer Center in Boston was in the process of launching a new type of clinical trial: an adaptive platform trial. Unlike the traditional randomized controlled trial, adaptive platform trials facilitate simultaneously studying multiple therapies for a given disease and have the potential to make clinical trials for new cancer drugs more efficient and accessible to patients. Developing questions around design, operations, and financing set the stage for this discussion with Harvard Business School professor Ariel Stern about her case: “Adaptive Platform Trials: The Clinical Trial of the Future?”

The African American CEO of a money management firm publicly criticizes the Fortune 500 for paying lip service to diversity. His board urges him to stop. What should he do? Harvard Business School professor Steven Rogers and protagonist John Rogers discuss Rogers’ new case, “John Rogers Jr. — Ariel Investments,” about the risks of speaking up, and the importance of black empowerment in the investment sector.

Oprah Winfrey believes in sharing the experiences that led her to become the wealthiest woman in the entertainment industry and the first African American woman billionaire. Harvard Business School professor Bill George discusses his case “Oprah!” about her growth from childhood, focusing on how and when she discovered her true voice and how that authenticity spurred her career success.