Let's go deeper into the world of ACS and the origin of the TIMI score and major adverse cardiac events "MACE" outcomes!

• The basics – what is acute coronary syndrome? (4:08)
• Clinical context matters – angina pectoris, atypical chest pain, and troponins (5:22)
• You can’t just “cath” everyone – risk stratification to identify patients with high mortality risk (9:42)
• TIMI isn’t perfect – the issues with the score and MACE outcomes (14:00)
• Review of teaching points (17:58)

For full transcript and show notes: https://www.coreimpodcast.com/2019/02/27/acute-coronary-syndrome-acs-and-the-timi-score/

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Dissect an interesting case and improve your clinical reasoning skills!

Time Stamps:

• New features in this episode [00:25]
• Data point 1: Early hypothesis generation? [03:20]
• Data point 2: Pertinent negatives? [11:18]
• Data point 3: Representativeness heuristic over-represented in medical education? [13:28]
• Data point 4: Economical hypothesis generation by expert clinicians [19:20]
• Data point 5: Diagnosing diagnostic error [22:10]
• Data point 6: Moving toward a final diagnosis [27:11]
• Case resolution [29:50]

For full transcript and show notes: https://www.coreimpodcast.com/2019/02/13/hoofbeats-47m-with-chest-pain/

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Solidify your knowledge on Barrett's Esophagus and more! Quiz yourself on the 5 pearls we will be covering:

* What is Barrett’s esophagus and why should we care? (4:12)

* Who do we screen for Barrett’s, and why? (8:41)

* How do we screen for Barrett’s and counsel? (13:50)

* How do we treat and monitor Barrett’s esophagus? (18:21)

* Take Aways (21:45)

* Throwback to trending troponins (23:05)

For full transcript of the podcast, show notes and references: https://www.coreimpodcast.com/?p=20875 (https://www.coreimpodcast.com/?p=20875)

Solidify your knowledge on Barrett's Esophagus and more! Quiz yourself on the 5 pearls we will be covering:

1. What is Barrett’s esophagus and why should we care? (4:12)
2. Who do we screen for Barrett’s, and why? (8:41)
3. How do we screen for Barrett’s and counsel? (13:50)
4. How do we treat and monitor Barrett’s esophagus? (18:21)
5. Take Aways (21:45)
6. Throwback to trending troponins (23:05)

For full transcript of the podcast, show notes and references: https://www.coreimpodcast.com/2019/01/30/5-pearls-on-barretts-esophagus/

Find the best disability insurance for you: https://www.patternlife.com/disability-insurance?campid=497840

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Dissect an interesting case and improve your clinical reasoning skills!

Time stamps:

• Player three has entered the game! [0:15]
• Case presentation, part 1 [1:20]
• First impressions [3:24]
• Rethinking another provider’s diagnosis [4:36]
• Interpreting the test of treatment [8:48]
• Keeping your instincts on a leash? [10:58]
• Case presentation, part 2 [12:33]
• Diagnostic schemas [14:30]
• Our discussant’s differential and the final diagnosis [17:46]
• Shira’s cognitive autopsy [23:02]

For full transcript and show notes: https://www.coreimpodcast.com/2019/01/16/hoofbeats-34m-with-fever-headache-and-myalgias/

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Solidify your knowledge on troponins and more! Quiz yourself on the 5 pearls we will be covering:

1. What aspects of the history are concerning in a patient with a positive troponin? (4:00)
2. What is the difference between the TIMI, GRACE, and HEART scores, and how should we use them in the evaluation of a patient with an elevated serum troponin? (8:42)
3. How does the change in troponin over time help with diagnosis, and what should we consider in a patient with uptrending troponins but an unremarkable ECG? (14:48)
4. What can a “negative but detectable” troponin tell you about any patient, not just those with suspected ACS? (21:31)
5. Pearls Recap (25:26)
6. Throwback – what are the first-line medications for alcohol use disorder? (28:36)

For full transcript of the podcast, show notes and references: https://www.coreimpodcast.com/2019/01/04/5-pearls-on-troponins/

Tags: chest pain, cardiology, myocardial infarction, acute coronary syndrome

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Let's dive deeper into the world of acetaminophen and fever and how it may work and patient outcomes

Time Stamps:

1. What data is there to support the use of acetaminophen as a fever reducer? (2:08)
2. Does acetaminophen improve patient outcomes? (4:30)
3. How does acetaminophen compare to other medications like NSAIDs? (9:56)
4. What is the mechanism of acetaminophen action? (10:50)
5. Review of teaching points (16:02)

For full show notes and transcript of audio: https://www.coreimpodcast.com/2018/12/19/mind-the-gap-on-acetaminophen-fevers-pathophysiology-and-patient-outcomes/

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Dissect an interesting case and think about the way clinicians think! Many clinical reasoning pearls here:

Time stamps:

1. Case [1:19]
2. Diagnostic weight [8:42]
3. Hypothesis driven reasoning [12:26]
4. Anomalous clinical data [19:30]
5. Final diagnosis [22:20]
6. Take away points [31:21]

Human Dx Case link: https://www.humandx.org/o/co7yrer3dim2y59t5c0sbd370?s=FEED

For show notes: https://www.coreimpodcast.com/2018/12/05/hoofbeats-43m-with-diarrhea/

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Women in medicine inspire us with what they would tell their younger selves. Some of the speakers with Shreya Trivedi MD @ShreyaTrivediMD at the Women in Medicine GirlMedLive Conference:

Qaali Hussein MD @QaaliHussein1 Clinical Pearl @ClinicalPearl Marguerite Duane MD @mduanemd Kate Prior MBBS @doctorwibble C. Nicole Swiner MD @docswiner Carmen Landrau MD @DrLandrau Jessica Willett MD @jkwillettmd Ilene Brenner MD @irb123 Joannie Yeh MD @BetaMomma Karen Davidson, Esq [email protected] Suzanne Feigofsky MD @DrSuzyFeigofsky GirlMedLive: https://www.girlmedmedia.com/

Episode page: https://www.coreimpodcast.com/2018/11/21/what-would-you-tell-your-younger-self/

Tags: career development, professional development, lifelong learning, burnout, imposter syndrome, mentorship, worklife balance

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Solidify your knowledge on Alcohol Use Disorder (AUD) treatment and more! Quiz yourself on the 5 pearls we will be covering:

1. Throwback: At what levels of drinking does unhealthy alcohol use start, and how do you screen for unhealthy alcohol use? (1:47)
2. What does the brief intervention and counseling part of SBIRT entail? (4:43)
3. What are the first line medications for AUD and contraindications to them? (11:11)
4. What are the second-line medications for AUD and their limitations? (18:14)
5. What new therapies are being studied for for alcohol use disorder? (22:09)
6. Pearls Recap (25:06)

For full transcript of the podcast, show notes and references: https://www.coreimpodcast.com/2018/11/07/5-pearls-on-treatment-of-alcohol-use-disorder/

tag: naltrexone, acamprosate, gabapentin, topiramate, SBIRT, neuromodulation, nalmafene, psychaedelics, audit-c

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