Let’s take your breath away… with a review on steroids in treating COPD exacerbations!

Time Stamps

1. How does GOLD (Global Initiative for Chronic Obstructive Lung Disease) define a COPD exacerbation? (2:44)
2. What outcomes do steroids actually improve in treating a COPD exacerbation? (5:08)
3. What is the evidence behind a 5 day steroid “burst”? (7:20)
4. Are IV steroids more powerful than PO? (9:00)

For full show notes: https://www.coreimpodcast.com/2018/05/30/mind-the-gap-steriods-in-copd/

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Solidify your understanding of contrast-induced nephropathy (CIN)! Quiz yourself on the 5 pearls we will be covering:

1. Are there diagnostic criteria for CIN? (2:11)
2. Is there a difference between exposure to intra-arterial vs. intra-venous contrast in terms of risk of CIN? (6:28)
3. What are the biggest risk factors for CIN? (14:48)
4. What preventive measures have been shown to best reduce the risk of CIN? (19:41)
5. Can ESRD patients on hemodialysis still suffer from CIN? (23:32)
6. Recap (25:49)

For full show notes: https://www.coreimpodcast.com/2018/05/16/5-pearls-contrast-induced-nephropathy/

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Dissect an interesting case and think about the way clinicians think! So many clinical reasoning pearls here:

1. Part 1 Case (2:05)
2. Framing bias (7:07)
3. Data-driving reasoning (11:48)
4. Hypothesis-driven approach (12:38)
5. Periodic paralysis syndromes (16:08)
6. Representativeness heuristic (17:26)
7. Part 2 Case (20:51)
8. Pivot Points (31:36)
9. Diagnosis (35:55)
10. Take aways (37:20)

Check out the key teaching points: https://www.coreimpodcast.com/2018/05/02/hoofbeats-a-36f-with-weakness/

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Solidify your knowledge on adrenal insufficiency! Quiz yourself on the 5 pearls we will be covering:

1. What are signs and symptoms of chronic adrenal insufficiency (AI)? What is the most sensitive? (2:02)
2. How do we diagnose and differentiate types of adrenal insufficiency? (6:05)
3. How sensitive and specific are the diagnostic tests for AI & at what cutoffs? (12:06)
4. Can we both test and treat adrenal insufficiency at the same time? (16:40)
5. Throwback: How do hypokalemia and hepatic encephalopathy connected? (24:55)
6. Dr. Nidhi Agrawal Recap (19:20)

For full show notes: https://www.coreimpodcast.com/2018/04/18/5-pearls-chronic-adrenal-insufficiency/

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Solidify your knowledge on latent TB! Quiz yourself on the 5 pearls we will be covering:

1. Who should be screened for latent tuberculosis infection (LTBI)? (1:45)
2. What screening tests are available and how do they differ? (6:30)
3. What are the LTBI treatment options available? (10:24)
4. What are the major adverse drug effects to consider? (13:28)
5. How frequently should you check liver function tests in a patient being treated for LTBI? What do you do with the results? 17:43
6. Dr. Caplan-Shaw Recap (21:29)

For full show notes: https://www.coreimpodcast.com/2018/03/28/5-pearls-latent-tuberculosis-infection/

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Solidify your knowledge on albuminuria! Quiz yourself on the 5 Pearls we will be covering:

1. How good is a dipstick, urinalysis and UACR in detecting albuminuria? (1:42)
2. What conditions that lead to transient proteinuria? What is the appropriate interval to recheck and how should be it be repeated? (5:14)
3. Who should be screened for albuminuria and can it prognosticate risk for cardiovascular mortality? (7:47)
4. Does increasing RAAS inhibition improve renal outcomes? (10:57)
5. Throwback Question: How do you prescribe oral iron and what tips do you tell your patients? (13:11)

For full show notes: https://www.coreimpodcast.com/2018/02/28/5-pearls-albuminuria/

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Let’s go deeper into to why we think about diseases the way we do: COPD Classifications through the years!

Time Stamps:

1. How did prior understanding of COPD pathophysiology lead to COPD classifications in the past? (3:25)
2. How is COPD diagnosed? (6:13)
3. How has COPD been classified and why? (6:42)

For full show notes: https://www.coreimpodcast.com/2018/02/14/mind-the-gap-copd-classifications/

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Quiz yourself on the following 5 Pearls on Chronic Hepatitis B (HBV) Management!

1. What is the focused history, physical and lab workup in a patient with chronic HBV? (1:40)
2. What is the best imaging to evaluate for intermediate stages of liver fibrosis? (4:06)

• What scoring tools can you use to estimate fibrosis and what are their limitations?

1. What factors do you use to assess which patients get treatment? (7:41)
2. What drugs are available for HBV treatment and how do you choose? (11:18)
3. Which chronic HBV patient should be screened for HCC, and how often? (14:45)

For full show notes: https://www.coreimpodcast.com/2018/01/31/5-pearls-on-chronic-hepatitis-b-2/

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Solidify your knowledge on Chronic Hepatitis B (HBV) screening and vaccinations! Quiz yourself on the 5 Pearls we will be covering:

1. Who do you screen for HBV? (3:37)

• How is HBV transmitted and who is at risk for HBV reactivation?

1. What tests do you order when screening for HBV?  (10:48)

• In which populations is HBV vaccination recommended?

1. What are the four possible meanings of an isolated positive total anti-HBc? (13:55)
2. In an asymptomatic adult, is it necessary to send an anti-HBc IgM to distinguish acute from chronic HBV infection? (15:01)
3. What are the implications of seroconversion of HBeAg from positive to negative? (16:19)

For full show notes: https://www.coreimpodcast.com/2018/01/17/5-pearls-on-chronic-hepatitis-b/

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Let's go deeper as to why we do what we do: albumin in spontaneous bacterial peritonitis (SBP) ! Time Stamps:1. How much albumin is recommended in SBP? (1:45)2. What antibiotics are used for the treatment of SBP? (2:30)3. Why do we give albumin in SBP? (4:15) - How does albumin compare to crystalloid? (7:15) - Do we always have to give to albumin? (9:00) For full shownotes: https://www.coreimpodcast.com/2018/01/03/mind-the-gap-albumin-in-sbp/

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