DOC Updates

Diabetes Core Update is a monthly podcast that presents and discusses the latest clinically relevant articles from the American Diabetes Association's four science and medical journals – Diabetes, Diabetes Care, Clinical Diabetes, and Diabetes Spectrum. Each episode is approximately 25 minutes long and presents 5-6 recently published articles from ADA journals.

Intended for practicing physicians and health care professionals, Diabetes Core Update discusses how the latest research and information published in journals of the American Diabetes Association are relevant to clinical practice and can be applied in a treatment setting.

Welcome to diabetes core update where every month we go over the most important articles to come out in the field of diabetes. Articles that are important for practicing clinicians to understand to stay up with the rapid changes in the field.

This issue will review:

1. Association between changes in carbohydrate intake and long term weight changes

2. Once-Weekly Insulin Icodec With Dosing Guide App Versus Once-Daily Basal Insulin Analogues in Insulin-Naive Type 2 Diabetes (ONWARDS 5)

3. Achieving Normoglycemia With Tirzepatide: Analysis of SURPASS 1–4 Trials

4. Tight Blood-Glucose Control without Early Parenteral Nutrition in the ICU The TGC-Fast study

5. Oral semaglutide 50 mg taken once per day in adults with overweight or obesity (OASIS 1)

For more information about each of ADA's science and medical journals, please visit www.diabetesjournals.org.

Hosts:

Neil Skolnik, M.D., Professor of Family and Community Medicine, Sidney Kimmel Medical College, Thomas Jefferson University; Associate Director, Family Medicine Residency Program, Abington Jefferson Health

John J. Russell, M.D., Professor of Family and Community Medicine, Sidney Kimmel Medical College, Thomas Jefferson University; Director, Family Medicine Residency Program, Chair-Department of Family Medicine, Abington Jefferson Health

In this second special episode on The Importance of Nutrient-Dense Diets, our host, Dr. Neil Skolnik will moderate further discussion with two experts about the role of nutrition in the prevention and management of diabetes and related complications, as well as challenges in implementing and sticking to healthy dietary strategies of some things we can do to help our patients adhere to a healthy diet.

This special edition of Diabetes Core Update is sponsored by Fresh Avocados - Love One Today. For more information, as well as diabetes-friendly mean plans and a free downloadable toolkit just go to: www.Loveonetoday.com/diabetes .

Presented by:

Neil Skolnik, M.D., Professor of Family and Community Medicine, Sidney Kimmel Medical College, Thomas Jefferson University; Associate Director, Family Medicine Residency Program, Abington Jefferson Health

Dr. Nikki Ford, PhD, Senior Director of the Avocado Nutrition Center.

Elizabeth Hanna, MS, RDN, CDCES.

In this special episode on Diabetes in a Geriatric Population, our host, Dr. Neil Skolnik will discuss diabetes in a geriatric population with Dr. Medha Munshi, Director of the Joslin Geriatric Diabetes Program, focusing on deintensification of therapy.

This special episode is supported by an independent educational grant from Sanofi.

Presented by:

Neil Skolnik, M.D., Professor of Family and Community Medicine, Sidney Kimmel Medical College, Thomas Jefferson University; Associate Director, Family Medicine Residency Program, Abington Jefferson Health

Medha Munshi, M.D., Director of the Joslin Geriatric Diabetes Program, Associate Professor of Medicine at Harvard Medical School

Diabetes Core Update is a monthly podcast that presents and discusses the latest clinically relevant articles from the American Diabetes Association's four science and medical journals – Diabetes, Diabetes Care, Clinical Diabetes, and Diabetes Spectrum. Each episode is approximately 25 minutes long and presents 5-6 recently published articles from ADA journals.

Intended for practicing physicians and health care professionals, Diabetes Core Update discusses how the latest research and information published in journals of the American Diabetes Association are relevant to clinical practice and can be applied in a treatment setting.

Welcome to diabetes core update where every month we go over the most important articles to come out in the field of diabetes. Articles that are important for practicing clinicians to understand to stay up with the rapid changes in the field. I'm Dr, Neil Skolnik and …

This issue will review:

1. Efficacy and safety of co-administered once-weekly cagrilintide 2·4 mg with once-weekly semaglutide 2·4 mg in type 2 diabetes: a multicentre, randomised, double-blind, active-controlled, phase 2 trial

2. Association Between Diabetes Technology Use and Glycemic Outcomes in Adults With Type 1 Diabetes Over a Decade

3. Efficacy and Safety of IDegLira Versus Basal- Bolus in Patients With Poorly Controlled Type 2 Diabetes and Very High HbA1c

4. Retatrutide, a GIP, GLP-1 and glucagon receptor agonist, for people with type 2 diabetes

For more information about each of ADA's science and medical journals, please visit www.diabetesjournals.org.

Hosts:

Neil Skolnik, M.D., Professor of Family and Community Medicine, Sidney Kimmel Medical College, Thomas Jefferson University; Associate Director, Family Medicine Residency Program, Abington Jefferson Health

John J. Russell, M.D., Professor of Family and Community Medicine, Sidney Kimmel Medical College, Thomas Jefferson University; Director, Family Medicine Residency Program, Chair-Department of Family Medicine, Abington Jefferson Health

In this special episode on Residual Risk: A Focus on Triglycerides, our host, Dr. Neil Skolnik will discuss Residual Risk, Triglycerides and how to reduce residual risk with Dr. Christie Ballantyne, Director of the Center for Cardiometabolic Disease Prevention, Baylor College of Medicine.

This special episode is supported by an independent educational grant from Amarin.

Presented by:

Neil Skolnik, M.D., Professor of Family and Community Medicine, Sidney Kimmel Medical College, Thomas Jefferson University; Associate Director, Family Medicine Residency Program, Abington Jefferson Health

Dr. Christie Ballantyne. Dr. Ballantyne is a Professor of Medicine-Cardiology, and Director of the Center for Cardiometabolic Disease Prevention, Baylor College of Medicine.

Selected references in the Podcast:

Niacin: AIM-HIGH - N Engl J Med 2011; 365:2255-2267

Omega-3 Fatty Acids: STRENGTH trial - JAMA. 2020;324(22):2268-2280

Pemafibrate: PROMINENT - N Engl J Med 2022; 387:1923-1934

Icosapent Ethyl: JELIS - Lancet. 2007;369(9567):1090-1098

Icosapent Ethyl: REDUCE-IT - N Engl J Med 2019; 380:11-22

ADA Standards of Care: Diabetes Care 2023;46(Supplement_1):S158–S190

2023 AHA/ACC/ACCP/ASPC/NLA/PCNA Guideline for the Management of Patients With Chronic Coronary Disease: Circulation. 2023;148. doi: 10.1161/CIR.0000000000001168

In this special episode on Diabetes in a Geriatric Population, our host, Dr. Neil Skolnik will discuss diabetes in a geriatric population with Dr. Medha Munshi, Director of the Joslin Geriatric Diabetes Program.

This special episode is supported by an independent educational grant from Sanofi.

Presented by:

Neil Skolnik, M.D., Professor of Family and Community Medicine, Sidney Kimmel Medical College, Thomas Jefferson University; Associate Director, Family Medicine Residency Program, Abington Jefferson Health

Medha Munshi, M.D., Director of the Joslin Geriatric Diabetes Program, Associate Professor of Medicine at Harvard Medical School

Diabetes Core Update is a monthly podcast that presents and discusses the latest clinically relevant articles from the American Diabetes Association's four science and medical journals – Diabetes, Diabetes Care, Clinical Diabetes, and Diabetes Spectrum. Each episode is approximately 25 minutes long and presents 5-6 recently published articles from ADA journals.

Intended for practicing physicians and health care professionals, Diabetes Core Update discusses how the latest research and information published in journals of the American Diabetes Association are relevant to clinical practice and can be applied in a treatment setting.

This issue will review:

1. Long-term Weekly Icodec versus Daily Glargine U100 in Type 2 Diabetes without Previous Insulin

2. Triple – Hormone-Receptor Agonist Retatrutide for Obesity — A Phase 2 Trial

3. Effects of Tirzepatide Versus Insulin Glargine on Cystatin C–Based Kidney Function

4. Relationship Among Diabetes, Obesity, and Cardiovascular Disease Phenotypes Complications

5. Tirzepatide Once Weekly for the Treatment of Obesity in People with Type 2 Diabetes (SURMOUNT-2): a Phase 3 Trial

For more information about each of ADA's science and medical journals, please visit www.diabetesjournals.org.

Presented by:

Neil Skolnik, M.D., Professor of Family and Community Medicine, Sidney Kimmel Medical College, Thomas Jefferson University; Associate Director, Family Medicine Residency Program, Abington Jefferson Health

John J. Russell, M.D., Professor of Family and Community Medicine, Sidney Kimmel Medical College, Thomas Jefferson University; Director, Family Medicine Residency Program, Chair-Department of Family Medicine, Abington Jefferson Health

Diabetes Core Update is a monthly podcast that presents and discusses the latest clinically relevant articles from the American Diabetes Association's four science and medical journals – Diabetes, Diabetes Care, Clinical Diabetes, and Diabetes Spectrum. Each episode is approximately 25 minutes long and presents 5-6 recently published articles from ADA journals.

Intended for practicing physicians and health care professionals, Diabetes Core Update discusses how the latest research and information published in journals of the American Diabetes Association are relevant to clinical practice and can be applied in a treatment setting.

This issue:

1. Long-term effect of intensive lifestyle intervention on cardiometabolic risk factors and microvascular complications in patients with diabetes in real-world clinical practice: a 10-year longitudinal study

2. Comparison of seven popular structured dietary programmes and risk of mortality and major cardiovascular events in patients at increased cardiovascular risk: systematic review and network meta-analysis

3. Beverage consumption and mortality among adults with type 2 diabetes: prospective cohort study

4. Higher Severe Mental Illness and Type 2 Diabetes Outcomes and Complications

5. High Prevalence of NASH and Advanced Fibrosis in Type 2 Diabetes: A Prospective Study of 330 Outpatients Undergoing Liver Biopsies for Elevated ALT

6. COVID-19 to Blame? Trends of Incidence and Sex Ratio in Youth-Onset Type 2 Diabetes

For more information about each of ADA's science and medical journals, please visit www.diabetesjournals.org.

Presented by:

Neil Skolnik, M.D., Professor of Family and Community Medicine, Sidney Kimmel Medical College, Thomas Jefferson University; Associate Director, Family Medicine Residency Program, Abington Jefferson Health

John J. Russell, M.D., Professor of Family and Community Medicine, Sidney Kimmel Medical College, Thomas Jefferson University; Director, Family Medicine Residency Program, Chair-Department of Family Medicine, Abington Jefferson Health

Diabetes Core Update is a monthly podcast that presents and discusses the latest clinically relevant articles from the American Diabetes Association's four science and medical journals – Diabetes, Diabetes Care, Clinical Diabetes, and Diabetes Spectrum. Each episode is approximately 25 minutes long and presents 5-6 recently published articles from ADA journals.

Intended for practicing physicians and health care professionals, Diabetes Core Update d iscusses how the latest research and information published in journals of the American Diabetes Association are relevant to clinical practice and can be applied in a treatment setting.

This issue will review:

1. Bempedoic Acid and Cardiovascular Outcomes in Statin-Intolerant Patients

2. Cardiovascular and Renal Benefits of Novel Diabetes Drugs by Baseline Cardiovascular Risk: A Systematic Review

3. Deintensifying Diabetes Medications for Older Adults With Type 2 Diabetes

4. Higher Neighborhood Drivability Is Associated With a Higher Diabetes Risk in Younger Adults

5. Quantifying the Relationship Between Physical Activity Energy Expenditure and Incident Type 2 Diabetes: A Prospective Cohort Study

6. Weekly Glycemic Control Over Multiple Decades and Dementia Risk in People With Type 2 Diabetes

For more information about each of ADA's science and medical journals, please visit www.diabetesjournals.org.

Presented by:

Neil Skolnik, M.D., Professor of Family and Community Medicine, Sidney Kimmel Medical College, Thomas Jefferson University; Associate Director, Family Medicine Residency Program, Abington Jefferson Health

John J. Russell, M.D., Professor of Family and Community Medicine, Sidney Kimmel Medical College, Thomas Jefferson University; Director, Family Medicine Residency Program, Chair-Department of Family Medicine, Abington Jefferson Health