In this week’s View, Dr. Eagle highlights a study comparing a proteomics-based risk model to a traditional risk factor model in predicting recurrent atherosclerotic events in two observational cohorts, He also discusses the prevalence of noncalcified and calcified plaque in symptomatic adults and its association with cardiovascular disease (CVD) events across the low-density lipoprotein cholesterol (LDL-C) spectrum. And finally, Dr. Eagle reviews the effects of empagliflozin on heart failure hospitalizations across the full range of left ventricular ejection fractions.